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1 2007년 5월 10일(목) ~ 12일(토), 그랜드힐튼호텔 주최:

2 CONTENTS Treatment of Prediabetes and Metabolic Syndrome Invitation Time Table Daily Program Session Overview Social Program Registration & Oral Presentation Floor Plan Accommodations Important Dates

3 Invitation 안녕하십니까? 꽃이 만발하여 향기 가득한 4월입니다. 항상 건강 하시고, 선생님께 좋은일만 가득하 시길 바랍니다. 이번 대한당뇨병학회 제20차 춘계학술대회는 "Treatment of Prediabetes and Metabolic Syndrome"이라는 주제로 5월 10일(목) ~ 12일(토) 까지 그랜드힐튼 호텔에서 개최됩니다. 이번 춘계학술대회 Plenary Lecture에는 세계적인 석학이신 Gerald I. Shulman (Yale University, USA) 교수와 Boyd E. Metzger (Northwestern University, USA) 교수, 그리고 George L. King (Harvard University, USA) 교수를 초청하여 강의를 마련했습니다. Main Symposium은 총 5개의 분야로 나뉘어 진행되며 기초연구부터 약물치료에 이르기까지 폭 넓은 주제를 다룰 예정입니다. 이 밖에도 교육자 학술강좌와 수련위원회 연수강좌를 비롯하여 여러 위원회 및 소연 구회 심포지엄이 준비되어 있어 여러 분야에서 당뇨병환자의 교육과 치료에 힘쓰시 는 모든 참가자에게 다양한 지적 호기심을 충족시키고 유익한 정보를 제공할 것으로 기대하고 있습니다. 모쪼록 회원 여러분들의 많은 참여와 성원을 부탁 드립니다. 감사합니다. 2007년 4월 대한당뇨병학회 회장 대한당뇨병학회 이사장 김용기 손호영 01

4 Time Table Room 15:00~17:00 17:00~19:00 19:00-07:00~08:00 08:00-08:00~09:30 09:30~09:50 09:50~10:00 10:00~11:00 11:10~12:40 12:40~13:00 13:00~14:00 14:00~15:00 Room A I Convention Hall, 4F Welcome Reception Room AII Convention Hall, 4F Opening Address Plenary Lecture I Gerald I. Shulman (Yale Univ., USA) Main Symposium I New Drug Target I Luncheon Lecture I Plenary Lecture II Body E. Metzger (Northwestern Univ., USA) Coffee Break Room B Convention Hall, 4F Satellite Symposium I, II Breakfast Symposium I Special Symposium Innovative Technology for Diabetes Management Oral-Presentation I Room C Grand Ballroom, 4F Luncheon Lecture II 15:10~17:10 Highlight Oral Session I Highlight Oral Session II Main Symposium II Non-Pharmacological Treatment 17:10~17:30 Coffee Break 17:30~19:00 19:00-07:00~08:00 Breakfast Symposium II 08:00-08:00~09:00 Oral-Presentation II Sponsored Special Lecture 09:10~11:10 11:10~11:30 11:30~11:50 11:50~12:10 12:10~13:10 13:10~14:10 14:20~16:20 Main Symposium III Pharmacological Treatment I Luncheon Lecture III Plenary Lecture III George L. King (Harvard Univ., USA) Closing Main Symposium IV Pharmacological Treatment II Main Symposium V New Drug Target II Coffee Break Oral-Presentation III Luncheon Lecture IV 02

5 The 20 th Spring Congress of Korean Diabetes Association Daily Program Room A, ( AI, AII ) - Convention Hall, 4F Room B - Convention Hall, 4F Room C - Grand Ballroom, 4F Main Theme: Treatment of Prediabetes and Metabolic Syndrome May 10 (Thu) 15:00-17:00 Registration May 11 (Fri) 17:00-18:00 B Satellite Symposium I The introduction of a new era in the management of patients with type 2 diabetes DPP-4 inhibitors: a new class of oral agents to treat patients with type 2 diabetes Achieving the superior treatment goal for dyslipidemia patients with diabetes: powerful evidence of inhibiting two sources of cholesterol in "VYTAL study" 18:00-19:00 B Satellite Symposium II Diabetic heart disease, diabetic cardiomyopathy: the search for a unifying hypothesis The changing scenario in diabetic heart and its management 19:00- A Welcome Reception Gary D. Lopaschuk (University of Alberta, Canada) May 11 (Fri) 07:00-08:00 B Breakfast Symposium I Ideal basal insulin-asian LEAD to prove it 08:00- Registration 08:00-09:30 AI Insulin resistance and metabolic syndrome The role of mitochondrial dysfunction in metabolic syndrome Kitt F. Petersen (Yale University, USA) Gestational diabetes and future metabolic syndrome: What are the issues? Current status of metabolic syndrome in Korea Boyd E. Metzger (Northwestern University, USA) Treatment of Prediabetes and Metabolic Syndrome 08:00-09:30 AII Strategies for pancreatic beta-cell protection and regeneration Involvement of Ca 2+ - mediated apoptotic signals in palmitate-induced MIN6N8a beta cell death Immunoprotection of transplanted pancreatic islets using PEGylation The gut-pancreas connection and its relevance to diabetes Josephine M. Egan (National Institute of Health, USA) 03

6 Daily Program 08:00-09:30 B Special Symposium Innovative technology for diabetes management Rationale behind treatment with insulin pumps and continuous glucose monitoring Lristen Norgaard (Hvidovre Hospital, Denmark) Choosing a path on the journey to a fully automated closed loop insulin delivery system Garry Steil (Meditronics Minimed, USA) 08:00-09:30 C Clinical features of Japanese patients with type 2 diabetes from Japan Diabetes Complications Study (JDCS) Hirohito Sone (Ochanomizu University, Japan) Panel discussion 09:30-09:50 Coffee Break 09:50-10:00 A Opening Address 10:00-11:00 A Plenary Lecture I The pathogenesis of insulin resistance and metabolic syndrome Gerald I. Shulman (Yale University, USA) 11:10-12:40 A Main Symposium I - New Drug Target I Treatment of type 2 diabetes Kitt F. Petersen (Yale University, USA) New roles of an old enzyme: NAD(P)H:quinone oxidoreductase 1 as an interesting drug target for metabolic syndrome Modulation of insulin sensitivity by DGAT1 and triglyceride synthesis in skeletal muscle Yi-Hao Yu (Columbia University, USA) 11:10-12:40 B Oral Presentation I 11:10-12:40 C Diabetes in young women 12:40-13:00 A 04

7 The 20 th Spring Congress of Korean Diabetes Association Room A, ( AI, AII ) - Convention Hall, 4F Room B - Convention Hall, 4F Room C - Grand Ballroom, 4F 3L - 3F Lobby 13:00-14:00 A Luncheon Lecture I "Where do we go from here" in lipid management 13:00-14:00 C Luncheon Lecture II Reducing cardiovascular disease in patients with type 2 DM - CHICACO study A 14:00-15:00 Plenary Lecture II Mothers with diabetes, obesity or malnutrition have offspring with metabolic syndrome. Can similar mechanisms be involved? Boyd E. Metzger (Northwestern University, USA) 15:10-17:10 AI Highlight Oral Session I 15:10-17:10 AII Highlight Oral Session II 15:10-17:10 B Main Symposium II - Non-Pharmacological Treatment Novel mediators of skeletal muscle metabolism: AMPK, LKB1 and TRB3 Laurie J. Goodyear (Harvard University, USA) Exercise management for non-diabetic and diabetic obese patients Dietary management for non-diabetic and diabetic obese patients 15:10-16:40 C 17:10-17:30 Coffee Break 17:30-19:00 3L 19:00- C Treatment of Prediabetes and Metabolic Syndrome May 12 (Sat) B 07:00-08:00 Breakfast Symposium II Recent outcome trials and their impacts on paradigm of diabetes management 08:00- Registration Peter Grant (University of Leeds, UK) 05

8 Daily Program 08:00-09:00 AI Diabetes in Korea 2007, 1st Edition 08:00-09:00 AI Mitochondrial oxidative dysfunction in the diabetic macrovascular complications Anti-oxidative and anti-inflammatory effects of phosphodiesterase type III inhibitor -Lipoic acid suppresses endothelial cell senescence by elevating nitric oxide production 08:00-09:00 B Oral Presentation II 08:00-09:00 C Sponsored Special Lecture Clinical endocrinology of DPP-4 inhibitors 09:10-11:10 A Main Symposium III - Pharmacological Treatment I The role of the endocannabinoid system in food intake and metabolic regulation: Basic and clinical concepts Gary Wittert (University of Adelaide, Australia) The optimizing strategies to treat obesity and metabolic syndrome for Korean obese patients Understanding incretins and the role of improving metabolic syndrome Potential of the new DPP-4 inhibitors in metabolic syndrome 09:10-11:10 B Oral Presentation III 09:10-11:10 C 11:10-11:30 Coffee Break 11:30-11:50 A 06

9 The 20 th Spring Congress of Korean Diabetes Association Room A, ( AI, AII ) - Convention Hall, 4F Room B - Convention Hall, 4F Room C - Grand Ballroom, 4F 11:50-12:10 A 12:10-13:10 A Luncheon Lecture III Levemir : Weighing the evidence from clinical trials to clinical practice Per Clauson (Novo Nordisk Japan, Japan) 12:10-13:10 C Luncheon Lecture IV To evaluate Diovan (valsartan) for the effects on BP, microalbuminuria in Korean type 2 DM patients 13:10-14:10 A Plenary Lecture III Selective vascular insulin resistance: concepts for cardiovascular risks in diabetes and metabolic syndrome George L. King (Harvard University, USA) 14:20-16:20 AI Main Symposium IV - Pharmacological Treatment II Approaches to insulin sensitization - Beyond PPAR ligands Peter Grant (University of Leeds, UK) Angiotensin receptor blockers: New considerations in their mechanism of action in focus of treatment of metabolic syndrome Bobby V. Khan (Emory University, USA) Beyond lipid lowering agent: The role of lipid-lowering drugs in managing CVD risk in diabetes Paul N. Durrington (University of Manchester, UK) Metabolic dysregulation as a cause for contractile dysfunction of the heart in obesity and diabetes: Is this a potential target for therapy? Gary D. Lopaschuk (University of Alberta, Canada) 14:20-16:20 AII Main Symposium V - New Drug Target II Ceramide modulates lipid and glucose metabolism in cardiovascular system: New therapeutic target for cardiovascular disease (Columbia University, USA) Pyruvate dehydrogenase kinase 4 as a major determinant of skeletal muscle insulin sensitivity (University of Southern California, USA) Enhancing fat oxidation and inhibiting fat synthesis may offer potential therapeutic strategies for obesity and the metabolic syndrome (Yale University, USA) Molecular targets for the treatment of metabolic syndrome Synopsis 14:20-16:20 B Treatment of Prediabetes and Metabolic Syndrome 07

10 Session Overview Main Symposium - New Drug Target New Drug Target I Treatment of type 2 diabetes Kitt F. Petersen (Yale University, USA) New roles of an old enzyme: NAD(P)H:quinone oxidoreductase 1 as an interesting drug target for metabolic syndrome Modulation of insulin sensitivity by DGAT1 and triglyceride synthesis in skeletal muscle Yi-Hao Yu (Columbia University, USA) New Drug Target II Ceramide modulates lipid and glucose metabolism in cardiovascular system: New therapeutic target for cardiovascular disease (Columbia University, USA) Pyruvate dehydrogenase kinase 4 as a major determinant of skeletal muscle insulin sensitivity (University of Southern California, USA) Treatment strategies for metabolic syndrome: Is blocking fat synthesis or enhancing fat burning the better target? (Yale University, USA) Molecular targets for the treatment of metabolic syndrome Synopsis 08

11 The 20 th Spring Congress of Korean Diabetes Association Main Symposium - Pharmacological Treatment Pharmacological Treatment I The role of the endocannabinoid system in food intake and metabolic regulation: Basic and clinical concepts Gary Wittert (University of Adelaide, Australia) The optimizing strategies to treat obesity and metabolic syndrome for Korean obese patients Understanding incretins and the role of improving metabolic syndrome Potential of the new DPP-4 inhibitors in metabolic syndrome Pharmacological Treatment II Approaches to insulin sensitization - Beyond PPAR ligands Peter Grant (University of Leeds, UK) Angiotensin receptor blockers: New considerations in their mechanism of action in focus of treatment of metabolic syndrome Bobby V. Khan (Emory University, USA) Treatment of Prediabetes and Metabolic Syndrome Beyond lipid lowering agent: The role of lipid-lowering drugs in managing CVD risk in diabetes Paul N. Durrington (University of Manchester, UK) Metabolic dysregulation as a cause for contractile dysfunction of the heart in obesity and diabetes: Is this a potential target for therapy? Gary D. Lopaschuk (University of Alberta, Canada) 09

12 Session Overview Main Symposium - Non-Pharmacological Treatment Non-Pharmacological Treatment Novel mediators of skeletal muscle metabolism: AMPK, LKB1 and TRB3 Laurie J. Goodyear (Harvard University, USA) Exercise management for non-diabetic and diabetic obese patients Dietary management for non-diabetic and diabetic obese patients Special Symposium Innovative Technology for Diabetes Management Rationale behind treatment with insulin pumps and continuous glucose monitoring Lristen Norgaard (Hvidovre Hospital, Denmark) Choosing a path on the journey to a fully automated closed loop insulin delivery system Garry Steil (Meditronics Minimed, USA) 10

13 The 20 th Spring Congress of Korean Diabetes Association Committee Symposium Insulin resistance and metabolic syndrome The role of mitochondrial dysfunction in metabolic syndrome Kitt F. Petersen (Yale University, USA) Gestational diabetes and future metabolic syndrome: What are the issues? Boyd E. Metzger (Northwestern University, USA) Current status of metabolic syndrome in Korea Strategies for pancreatic beta-cell protection and regeneration Treatment of Prediabetes and Metabolic Syndrome Involvement of Ca 2+ - mediated apoptotic signals in palmitate-induced MIN6N8a beta cell death Immunoprotection of transplanted pancreatic islets using PEGylation The gut-pancreas connection and its relevance to diabetes Josephine M. Egan (National Institute of Health, USA) 11

14 Session Overview Committee Symposium Clinical features of Japanese patients with type 2 diabetes from Japan Diabetes Complications Study? (JDCS) Hirohito Sone (Ochanomizu University, Japan) Panel discussion 12

15 The 20 th Spring Congress of Korean Diabetes Association Committee Symposium Diabetes in Korea 2007, 1st Edition Treatment of Prediabetes and Metabolic Syndrome Mitochondrial oxidative dysfunction in the diabetic macrovascular complications Anti-oxidative and anti-inflammatory effects of phosphodiesterase type III inhibitor -Lipoic acid suppresses endothelial cell senescence by elevating nitric oxide production 13

16 Session Overview Committee Symposium 14

17 The 20th Spring Congress of Korean Diabetes Association 2007년 5월 10일(목) ~ 12일(토) / 그랜드힐튼호텔 Social Program 5월 10일 (목) Satellite Symposium I, II 시 간 : 17:00~19:00 장 소 : Room B 후 원 : MSD, Servier Welcome Reception 시 간 : 19:00 ~ 장 소 : Room A 5월 11일 (금) Breakfast Symposium I 시 간 : 07:00~08:00 장 소 : Room B 후 원 : Sanofi-Aventis 시 간 : 13:00~14:00 장 소 : Room A, C 후 원 : Astra Zeneca, Lilly 만 찬 시 간 : 19:00 ~ 장 소 : Room C 5월 12일 (토) Breakfast Symposium II 시 간 : 07:00~08:00 장 소 : Room B 후 원 : GSK Treatment of Prediabetes and Metabolic Syndrome Luncheon Symposium I, II Luncheon Symposium III, IV 시 간 : 12:10~13:10 장 소 : Room A, C 후 원 : Novo Nordisk, Novartis 15

18 Registration & Oral Presentation 16

19 Floor Plan Convention Center 3F Poster Exhibition : 3F Lobby Booth Exhibition : 3F Emerald Hall/ Diamond Hall Convention Center 4F Swan Room Board Room Room AI : 4F Convention Hall Room AII : 4F Convention Hall Room B : 4F Convention Hall Room C : Grand Ballroom, 2F Hotel Preview, Secretariat : Peacock Room Meeting Room : Swan, Board Room Booth Exhibition : 4F The Front of Grand Ballroom 17

20 The 20 th Spring Congress of Korean Diabetes Association Accommodations Treatment of Prediabetes and Metabolic Syndrome 18

21

22 20th Spring Congress of Korean Diabetes Association Treatment of Prediabetes and Metabolic Syndrome May 10-12, 2007, Seoul, Korea Room 1010, Renaissance Tower Bldg 456, Gongdeok-dong, Mapo-ku, Seoul, , Korea TEL / FAX / diabetes@kams.or.kr, jhchoi@kimsonline.co.kr

May 10~ Hotel Inter-Burgo Exco, Daegu Plenary lectures From metabolic syndrome to diabetes Meta-inflammation responsible for the progression fr

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