ι대한방사선의학호 지 1997: 37: 간좌엽의동맥조영술시위장공기충만의진단적가치 l 강성권 2 임명관 2 김원홍 2. 윤현기 서창해 2 송호영 성규보 목 적 : 간동액의혈관조영시자주보는해부학적변이인부좌위동맥과좌위동맥에서기 시하는좌간동맥에의한함정을극복하기위

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1 ι대한방사선의학호 지 1997: 37: 간좌엽의동맥조영술시위장공기충만의진단적가치 l 강성권 2 임명관 2 김원홍 2. 윤현기 서창해 2 송호영 성규보 목 적 : 간동액의혈관조영시자주보는해부학적변이인부좌위동맥과좌위동맥에서기 시하는좌간동맥에의한함정을극복하기위한방법으로위장공기충만술의효과를알아보 고자하였다. 대상및방법. 부좌위동맥이있는 15 예와, 좌위동맥에서기시하는좌간동액이있는 7 예 를대상으로하였으며먼저고식적인방법으로선택적간동맥조영술을시행한후위에서 기술한해부학적변이가발견되면상부위장관조영을시행할때사용하는발포제를소량의 물과합께먹여위를팽창시킨후다시혈관조영검사를시행하였다. 결 과 복강동맥의분지에서기시하는부좌위동맥이있는 1 5 예중 8 예에서간의좌엽외 측부에결절양염색이보였으며, 발포제를먹인후혈관조영검사에서 7 예에서는위의결절양염색으로 1 예에서는간의병변으로확인되였다. 좌간동맥이좌위동맥에서기시하는 7 예중 5 예에서는간의좌엽에겹쳐보이던위의염색이위가팽창됨으로간의좌엽과분리되 보임으로간의좌엽을관찰하는데도움이되었으며, 1 예에서는팽창된위를통해간의좌엽 병변을관찰하기가용이하였다. 나머지 l 예에서는위의정맥들과간좌엽의결절성병변을 구별하기힘든경우가있였는데, 발포제를먹인후혈관조영검사에서 1 런결절들이관상으 로보이면서가지치는모양을보임으로정맥임을확인하였다. 결 론. 부좌위동맥에의한위의염색이결절양으로보여간좌엽병변과구별이어려운 경우와좌간동액이좌위동맥에서기시함으로위의염색이간의좌엽과겹쳐보임으로간좌 엽병변을식별하기어려운경우발포제를먹인후혈관조영검사는간편하고쉽게시행해볼 수있는방법이라고사료된다. DS- 간동맥혈관조영술은고식적방법보다사용이간단 하고, 다양한기능을가지고있으며특히그대조도가뛰어남으 로최근널리이용되고있으나 DS- 간동맥혈관조영술의단 점으로허상과함정이있을수있다. 대표적으로심장박동, 호 흡등에의한움직임에의해발생송 } 는허상이많다 (1). 대표적인 함정으로는혈관침뱀을동반한간암, 저혈관성간암의경우간 암에서전형적으로볼수있는신생혈관이나과혈관성병변으 로보이지않음으로위음성으로진단할수있으며, 미만성간암 의경우간경화에의한불균질한간의염색과감별이어려우며 간의좌엽을침범한경우에는심장의박동이나주위장기의염 색과겹쳐보임으로진단에어려움이있다 (5). 그이외에도간 동맥에해부학척변이가있는경우에도간동맥조영술의판독 어 l 함정이될수있다. 저자들은복강동맥에서기시하는부좌위동맥 (ccessory 1 울산대학교의과대학진단방사선과학교실 2 언하대학교의과대학방사선과학교실 이논문은 년 5 월 20 일접수하여 년 8 월 6 일에채택되었음 n left gastric artery) 이있는경우와, 좌간동맥의일부또는전부가좌위동맥에서기시하는경우간동맥조영술을시행할때간의좌엽병변을평가하기어려웠던적이있어이런해부학적변이가간동맥조영술판독에함정이될수있으리라생각하고이를극복할수있는방법이있는지알아보고자하였다. 대상및방법간암을주소로내원하여혈관조영검사흑은화학색전술을받은환자중부좌위동맥 (ccessory left gastric a rt ery) 으로생각되는혈관이좌간동맥에서기시하고이동맥에의해서간의좌엽외측부에결절성염색을보이는 1 5예와, 좌위동맥에서기시하는좌간동맥 (Replaced left hepatic artery from left gastric artery) 이있고간의좌엽에의심스러운병변이있는 7 예를대상으로하였다. DS - 간동맥조영술 ( Multistar TOP, Siemens Medical system, Erlangen, Germany) 을시행한후위에서기술한해부학적변이가발견되면상부위장관 F J

2 강성권오 1: 간조 } 엽의동맥조영술시위징공기층만의진단적가치 조영을시행할때사용하는발포제 l포 ( 탑발포, 태준 ) 를소량의물과함께먹여위를팽창시킨후다시혈관조영검사를시행하였다. 혈관조영검사는총간동맥조영술의경우조영제 (Ultravist, 한국쉐링, 한국 ) 는초당 5-7cc를이용하였으며좌간동맥조영술의경우 2-5cc를이용하여시행하였다. 혈관조영검사의분석은부좌위동맥이있고결절성염색이동반되어있는경우에서는먼저발포제를먹이기전과후에 (1 ) 혈관모양에변화가있는지를확인하였고, (2) 결절성염 색이이남아있는지혹은사라지는지를확인하였다. 좌간동액이좌위동맥에서기시하는경우에서는발포제를먹이기전과후에 (1) 간의좌엽에있는병변이계속보이는지 (2) 간의좌엽에있는병변의수가증가하거나감소하는지를확인하였다. 결과복강동맥의분지에서기시하는부좌위동액이있는 1 5예중전예에서발포제를먹인후혈관조영검사에서그분지의모양이변하여부좌위동액이라는것을확인할수있었으며그변화하는양상은작은분지들사이의거리가멀어지거나주위의혈관이나장기와의거리나위치가변하였다. 이중 8예에서간의좌엽외측부에투렷한결절양염색이보였으며, 발포제를먹인후혈관조영검사에서 l예에서결절양염색이그대로남아있어간의병변으로 (Fig. 1) 7예에서는결절양염색이사라져위기저부의결절양염색으로확인되었다 (Fig. 2). 1 5예중 7예에서는 l B Fig. 1.. Common hepatic arteriogram before ingestion of effervescent. Nodular staining(arrow) in peripheral portion of the left hepatic lobe is noted in arteriography. B. Common hepatic arteriogram after ingestion of effervescent. Nodular staining(arrow) in peripheral portion of the left hepatic lobe is still noted in arteriography after ingestion of effervescent agent. This nodular staining is true hepatocellular carcinoma in lateral segment of the left hepatic lobe. v..,r 1 써 * Fig. 2.. Common hepatic arteriogram before ingestion of effervescent. Nodular staining(arrow) in peripheral portion of the left hepatic lobe is noted. B. Common hepatic arteriogram after ingestion of effervescent. Nodular staining in peripheral portion of the left hepatic 10 be is disappeared in arteriography after ingestion of effervescent agent. This nodular staining is a nodular staining of the gastric fundus by the accessory left gastric artery from the left hepatic artery 찌ωB

3 α대한밤시선의학회지 1997; 37 : * 획 B Fig. 3. Left gastric arteriogram before() and after(b) ingestion of effervescent. More nodules are detected in arteriography after ingestion of effervescent agent v ':,,,. B Fig. 4. Left gastric arteriogram before() and after(b) ingestion of effervescent. Multiple nodules in arteriography before ingestion of effervescent agent were confirmed as tortuous venous structures of the stomach in arteriography after ingestion of effervescent agent 부좌위동맥에의한위의염색이뚜렷하게보이지않았거나삼각형또는다각형의모양으로보였으며, 이런염색들은발포제를먹인후혈관조영검사에서모두사라져위기저부의염색으로확인되였다. 좌간동맥이좌위동맥에서기시하고좌간엽에의심스러운병변이있던 7예중 5예에서는간의좌엽에의심스러운병변이있었으나위의염색이중첩되어간의좌엽병변을정확히알수없었으나발포제를먹이고난후의혈관조영검사에서중첩되보이먼위의염색이위가확장되면서없어져간의좌엽을더자세히볼수있었고병변이없다는것을확인할수있었다. 1예에서는간의좌엽에다수의의심스러운병변이있었으나위의염색때문에식별하기어려웠으나발포제를먹인후간의좌엽병변을관찰하기가용이하였고발포제를먹이기전보다팽창된위를통하여많은수의병변을볼수있었다 (Fig. 3). 1예에서는위의정맥들이결절양으로간의좌엽과겹쳐보임으로간좌엽 의결절성병변을의심하게하는경우가있었으나발포제를먹 인후혈관조영검사에서이런정맥들이측면으로보이면서가지치는모 0.]: 을보임으로정맥임을확인하였다 (Fig. 4). 고찰 DS- 간혈관조영검사는편리한방법으로널리사용되고있다. DS- 혈관조영검사의장점은우선높은대조도를들수있으며그외에도사용하기가쉽고다양한이용방법등이있다 (1). 그러나 DS 간혈관조영검사의판독시문제점으로허상과함정이있는데 DS 간혈관조영검사의허상은 (1) Misregistration 허상, (2) 움직임에의한허상이많다. Misregistration 허상은조영제를투입하기전마스크영상과조영제를투업후영상을강쇄촬영술영상 (Subtraction image) 을만들어내는데이때조영제투입전마스크영상을잘못만옮으로감쇄촬영술영상에서일부혈관이보이지않게되는것을뜻하며적절한마스크영상을적용함으로극복할수있다. 움

4 없강성권오 1: 간죄엽의동맥조영술시위장공기충민의진단적기치 직임에의한허상은심장박동, 호흡, 환자의전신움직임등에의해초래될수있다 (2-4). DS - 간혈관조영검사를판독함에있어서함정은 (1) 작은종괴에의한혈관침범 ( vascular invasion of small tumor), (2) 저혈관성종괴 (hypovascular tumor), (3) 미만성종양 (diffuse hepa tocellular carcinoma), (4) 전이암 (metastatic tumor), (4) 좌간엽병변 (i nvolvement of left lobe) 등으로혈관을침범한종괴나저혈관성종괴의경우에는간암에서볼수있는신생혈관이나과혈관성종괴를볼수없어위음성으로판독할수있으며, 미만성종괴의경우에는간경화에의한불균질한간의염색과구별하기가어렵고, 신세포암과같은과혈관성종괴가간에전이한경우에는간암과같은과혈관성종괴로보이므로전이암을간암으로오인할수있다. 간의좌엽병변의경우에는심장과위등의장기와접해있으으로이들의움직임이나염색에의해간의병변이가려보이지않으므로판독에주의를해야한다 (5). 그밖에도해부학적변이도 DS- 혈관조영검사의판독에서함정이될수있다. Kadir 에의하연복강동맥및간혈관의해부학적변이중부좌위동맥이있는경우는약 23%, 좌위동맥에서한개또는그이상의좌간동맥이기시동 } 는경우는약 11-12% 정도라고하였으며좌간동맥의전체또는일부가좌위동맥에서기시할수있으며이런경우에좌위동맥에서먼저위를공급하는분지들이기시하고좌위동맥의분지가좌간문맥의제대부까지주행한후간동맥을분지한다 (6). 저자들은복강동맥및간동맥주위의해부학적변이중부좌위동액이있는경우, 이부좌위동맥에의한위기저부의염색이간좌엽병변과유사하게보일수있으며, 이런경우발포제를먹인후혈관조영검사를시행하면위가팽창됨으로위기저부의결절성염색이없어짐으로간좌엽의병변과구별할수있었다. 좌위동맥에서좌간동맥이기시핸경우에는좌간엽을보기위해서는좌위동맥조영술을시행해야하는데좌위동맥조영술을시행할경우위와좌간엽이동시에조영됨으로좌간엽에위가겹쳐보임으로좌간엽의병변을자세히볼수없었다. 이런경우에도발포제를먹이고좌위동맥조영술을시행하면위가팽창함으로팽창된위를통해간의좌엽을자세히볼수있었다. 좌간엽에위의염색이겹쳐보이는것이외에좌간엽의결절성병변으로오인하게하는구조로위의정맥이있였는데발포제를먹이기전혈관조영검사에서좌간 엽에여러개의작은결절성병변이보이는경우가있었으며, 이 런결절성병변은정맥기까지오래동안사라지지않고보엄으 로간암의모양과는달랐으며, 발포제를먹이고난후의혈관 조영검사에서는구불구불한관상구조로바캠으로정액의단띤 이결절성병변과유사하게보였다는것을알수있었다. 간의유사병변특히좌엽의유사병변을감별하기위해서는 발포제를먹이는방법이외에혈관조영술기기의각도를변화시 켜주위의장기또는유사병변과간을분리하거나, 좌위동맥조 영검사시위의분지를지나간동맥만을선택적으로혈관조영 술을시행동 } 는방법을사용할수있을것으로생각된다. 이와 같이다 OJ 한방법은해부학적구조나시술의편리성등을고려 하여적절이선택하여사용하면간의병변을정확히진단하는 데도움이될것으로사료된다. 결론적으로부좌위동맥에의한위의염색이결절양으로보여 좌간엽병변과구별이어려운경우와좌간동맥이좌위동맥에서 기시함으로위의염색이간의좌엽과겹쳐보임으로간좌엽병 변을식별하기어려운경우발포제를먹인후혈관조영검사는 간편하고쉽게시행해볼수있는방법이라고사료된다. 참고문헌 1. Melvin PJ, Barry TK, Michael SV. ngiographic Equipment. In Stanley B. bram' 5 angiography. 4th ed. Boston: Little Brown, 1997: Toshizo K, Tadashi N, Makoto F, Naohiro H. et al. Reducing motion artifacts during hepatic DS. Radiol Technol 1994 ; Takahashi M, Shinzato J, Korogi Y, Fukui K, Ueno S, Horiba 1, Suzumura N. utomatic reregistration artifacts in digital subtraction angiography of the head and neck. cta Radiol Suppl 1986; 396: Rossi p, Simonetti G, Passariello R, Tempesta p, Pesce B, Pavone P, Castrucci M. Digtal celiac arteriography. Radiolo. 앙 1985; 154 : Marks WM, Jacobs RP, Goodman PC, Lim RC. Heptocellular carcmoma clinical and angiographic findings and predictablility for surgical resection. JR 1979 ; 132: Saadoon K. tlas of normal and variant angiographic anatomy. 1st ed. Philadelphia: Saunders, 1991:

5 대한밤시선의학호 II199?;3?: J Korean Radiol Soc 199?; 3? : Diagnostic Efficacy of Gastric ir Filling in Hepatic rteriography of the Left Lobe l Sung-Gwon Kang, M.D. 2, Myung-Gwan Lim, M.D. 2, Won Hong Kim, M.D. 2 Hyun Ki Yoon, M.D., Chang-Hae Suh, M.D. 2 Ho-Young Song, M.D., Kyu Bo Sung, M.D. 1 Department of Radi% 잉 ι san Medica/ Center, University of U/san college of Medicine 2Inha University Hospita/, Department of Radi%. 용 Purpose: To evaluate the diagnostic efficacy of gastric air filling during DS-hepatic arteriography of the left lobe in overcoming the pitfalls caused by accessory left gastric artery and left hepatic artery from left gastric artery Materials and Methods: In a prospective study, standard hepatic arteriogram and hepatic arteriogram after ingestion of an effervescent agent were performed in 22 patients with anatomic variation of the celiac axis. The anatomic variations were accessory left gastric artery in 15 patients and left hepatic artery from left gastric artery in seven. Results: Hepatic arteriogram after ingestion of an effervescent agent was excellent in differentiating nodular stomach staining from hepatic tumor staining in the left hepatic lobe in patients with accessory left gastric artery, and for evaluation of the left hepatic lobe when this was obscured by stomach staining. Conclusion : Hepatic arteriogram after ingestion of an effervescent agent is a simple and safe method for overcoming angiographic pitfalls due to anatomic variation. Index Words: Hepatic arteries Digital subtraction angiography ngiography, technology ddress reprint requests to: Sung-Gwon Kang, M.D., Department of Radiology, Inha university Hospital ~ Shinheung-Dong 3rd ST. Choong-Gu Inchon, , Korea. Tel Fax %

6 아시아지역방사선과의사의국내수련병원 Fellowship 안내 새로운국제질서가만들어지고급변하는국제관계속에아시아태평양시대의구조적역할을하는현재의우리나라는경제, 사회등모든분야에그위상이크게달라져있습니다. 그중의학학술분야에서는어느선진국못지않은세계적인수준이라자부할수있으며이제는배우는나라에서배움을주는나라로발전하였습니다. 이에대한방사선의학회에서는중국을포함한아시아각국방사선과의학도들올선발하여학문적 수준과시설이나은우리나라연수기관에서 6개월에서 1 년동안수련시켜우리나라방사선의학의 수준을세계여러나라에과시하고나아가아시아국가간협력과우호증진및학술교류에도기여하 고자합니다. 이에소요되는제반비용은삼성 GE 의료기기의후원으로이루어집니다. 여러수련병원에서는학회에서주굉하는이프로젝트에적극참여하시어대한방사선의학회의국 제화노력에협조하여주시기바랍니다. 참여희망신청 : 학회사무국또는대한방사선의학회국제협력위원회 문의사항 : 문의사항은대한방사선의학회국제협력위원회 ( 울산의대서울중앙병원진단방사선과소재 Tel. (02) FX: (02)4?6-4? r) 로문의하시기 바랍니다

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