sensitive 최상의감도제공 simple 간편한사용법과유지관리 small 어떠한 LC 와도사용가능 Grace Davison Discovery Sciences Brochure #5K From the Leader in Evaporative Light Scattering Detection
Introduction To ELSD Leading the Way in ELSD Technology for More than 0 Years Grace 계열사인 Alltech 은가장뛰어난 ELSD 의설계및제작노하우를가지고있다. 따라서, 우리의고객이 필요로하는새로운성능의혁신적인 ELSD 개발과설계프로그램을계속추진해나갈것이다. 985 MK II 988 MK IIA 99 MK III 994 MK IIIA 996 ELSD 500 997 ELSD LTA 000 ELSD 000 00 ELSD 800 004 ELSD 000ES 006 00 ELSD* *patent pending ELSD Advantages Universal 이동상보다비휘발성인어떠한시료도검출가능 더욱향상된정량분석 더욱정확해진순도분석 Sensitive 낮은검출한계 (Low nanogram) Gradient Compatible 어떠한기울기용리에서도안정된바탕선유지 Alltech ELSDs simplify analysis of difficult compounds: pharmaceuticals impurities phospholipids fatty acids surfactants nutraceuticals excipients amino acids triglycerides polymers carbohydrates ELSD Detection Process:. Nebulization 컬럼용리액이 needle을통과하면질소가스에의해작은방울형태로분산된다.. Evaporation 작은방울은가열된 drift tube를통과하면서이동상은기화되고용매증기로포획된시료입자는건조되어미세한입자를형성한다.. Detection 시료입자는쎌을통과하면서 laser에의해산란되며, 산란된광은검출되어신호를발생시킨다.
ELSD Advantages ELSD Advantages Over Other LC Detectors ELSD RI UV MS CHART KEY Sensitivity Gradient Capability Baseline Stability Solvent Interference Mass Balance Excellent: Good: Poor: ELSD 는 RI 와비교하여보다안정된바탕선과검출감도를제공한다. ELSD 는 UV 검출기에서볼수없는부분을정확히보여준다. Solvent Front Sugar Alcohols. Xylitol (00ppm). Sorbitol (00ppm). Dulcitol (00ppm) 067 065 Plant Oil Extract 0656 0657 ELSD ELSD RI 0 0 0 0 40 50 60 70 Min. UV at 54nm 0 4 6 8 0 4 6 8 Min. Column: Alltech Prevail Carbohydrate ES, 5µm, 50 x 4.6mm, (Part No. 50) Mobile Phase: Acetonitrile:Water (79:) Flow Rate:.0 ml/min Column Temp: 0 C Column: Alltech Alltima C8, μm, 50 x.mm, (Part No. 485) Mobile Phase: A: 0.% Formic Acid B: Methanol Gradient: Time: 0 40 %B: 60 00 Flow Rate: 0.5 ml/min Column Temp: 0 C ELSD 를 UV/Vis 및 MS 와연결하여사용하면시료에대한최상의구조와농도에대한자료를얻을수있다. ELSD 는 UV/Vis 보다더정확한시료의농도를얻을수있다.. Povidone (8 µg). Chlormadinone Acetate (.5 µg). Mestranol ( µg) Steroid Hormone Formulation 0 4 6 8 0 4 6 8 0 Min. ELSD MS UV at 54nm 069 064 0640. Mephobarbital (500ppm). Secobarbital (500ppm) : Mixture 0 4 6 8 0 4 6 8 0 Min. ELSD 067 066 UV at 0nm Column: Vydac Denali 8DE C8, µm, 50 x.mm, (Part No. 8DE05) Mobile Phase: 0.% Formic Acid in Acetonitrile:Water (55:45) Flow Rate: 0. ml/min Column: Alltech Alltima HP C8 HL, 5µm, 50 x 4.6mm, (Part No. 87698) Mobile Phase: Acetonitrile:Water (0:70) Flow Rate:.0 ml/min Column Temp: 45 C
Sensitive & Reproducible Alltech 00 ELSD 는다른어떠한 ELSD 보다더우수한감도와안정된바탕선, 그리고현저히낮아진 noise 수준을경험할수있다.. Methyl Paraben (00ng). Propyl Paraben (00ng). Butyl Paraben (00ng) Competitor S Competitor P Competitor W Butyl Paraben Model Limit of Detection (LOD) 00 ELSD 5ng Competitor S Competitor P Competitor W Competitor X 00ng 00ng 50ng 50ng Competitor X 00 ELSD Column: Alltech Alltima C8, 5µm, 50 x 4.6mm, (Part No. 88056) Mobile Phase: Water:Acetonitrile (40:60) Flow Rate:.0 ml/min 0 4 5 6 7 8 Min. 00 ELSD 는실온에가까운기화온도로 semi-volatiles 시료에대해최상의감도를제공한다. 00 ELSD 의재현성에대한우수성은 4 가지 Ginkgolide 성분의 0 회반복주입에따른결과로확인할수있다.. Ibuprofen (00ppm) Component % RSD. Bilobalide.7. Ginkgolide C.. Ginkgolide A.6 4. Ginkgolide B.0 0 Min. 0 C.5 C 5 C 7.5 C 40 C 4.5 C Column: Alltech Alltima HP C8, µm, 00 x.mm, (Part No. 87669) Mobile Phase: Acetonitrile: 0.%TFA in Water (80:0) Flow Rate: 0. ml/min 0 4 6 8 0 4 6 Min. Column: Alltech Platinum C8, 5µm, 50 x 4.6mm, (Part No. 064) Mobile Phase: Water:Methanol:THF (65:5:0) Flow Rate:.0 ml/min 4
Easy To Use 윈도우즈를기반으로한사용자인터페이스는메뉴를통하여쉽게조작할수있게해준다. 모든중요한조작변수와크로마토그램은 full color LCD 화면으로나타낸다. 단계적인 method 마법사는검출기의조작을더욱편리하게안내해준다. 사용자는 8 가지언어중에서선택할수있다. : English Español Francais Deutsch Italiano Japanese Chinese Korean An informative help function is available in each screen Additional Features: Agilent Chemstation 과 EZChrom Data 소프트웨어를통해데이터를디지털방식으로조작하고수집한다. 어떠한 HPLC 시스템과도사용할수있고크기가작아설치가자유롭다. GLP 요구사항을만족하기위한비밀보호화면과에러로그기능 빠른 method 설정을위한 00 개의 method 저장기능 coming soon
Easy To Maintain Maintenance Made Simple! 부품에대한클리닝서비스는검출기의전면에서쉽게접근할수있다. Nebulizer 는전면에서간단히돌려당기면제거된다. Drift tube 는사용자가쉽게브러쉬로세척할수있다. Onboard diagnostics automate the troubleshooting process Full IQ/OQ/PQ Protocols Included with each ELSD Alltech 은검증된 HPLC 시스템과 ELSD 를쉽게추가할수있도록제작하였다. 00 ELSD 는선적전에충분한테스트를거친검교정및 Performance 서류가각시스템마다포함되며, 자세한 IQ/OQ/PQ 과정은사용자자신이직접수행할수있는능력을부여하기위해제품과함께공급하고있다. 또한, Alltech 은서비스엔지니어에의한현장검증옵션을제공한다. 6
Applications Stable Baselines with Fast, Steep Gradients 0 Min.. Acetylsalicylic Acid. Diphenhydramine. Trimipramine 0658 Column: Alltech Alltima HP C8, µm, x 7mm, (Part No. 8767) Mobile Phase: A: 0.%TFA in Water B: 0.% TFA in Acetonitrile Gradient: Time: 0 %B: 0 90 Flow Rate:.5 ml/min Column Temp: 0 C Use ELSD to Trigger Collection of UV Transparent Compounds in Prep Applications 4 5 6 7,8 9,0 0 5 0 5 0 Min. Column: Vydac Denali 8DE C8, 0µm, 50 x mm, (Part No. 8DE05) Mobile Phase: A: Acetonitrile B: Dichloromethane Gradient: Time: 0 0 0 %B: 45 50 70 45 Flow Rate: 0 ml/min Column Temp: 5 C. LLLn. LLL. LLO 4. PLL 5. LOO 6. PLO 7. PLP 8. OOO 9. SLO 0. POO 0679 Simplify Detection of Weak Absorbing Polymers. mpeg-sba 066 Easily Detect Non-Chromophoric Drug Compounds 0680. Spectinomycin 0 6 9 5 Min. Column: Alltech ProSphere 00, 5µm, 50 x 4.6mm, (Part No. 5560) Mobile Phase: A: Water B: Acetonitrile Gradient: Time: 0 5 %B: 0 0 80 Flow Rate:.0 ml/min 0 4 5 6 7 8 9 Min. Column: Alltech Alltima HP C8 Amide, µm, 50 x 4.6mm, (Part No. 8789) Mobile Phase: 0mM Ammonium Carbonate:Acetonitrile (98:) Flow Rate:.0 ml/min Detect Difficult Samples without Derivatizing Improve Sensitivity for Carbohydrates Biodiesel Derived from Soy Bean Oil 4 6 7 9 8 5 0 0 5 0 5 0 5 0 Min. 0644. Mono-acylglycerol (MAG). MAG. MAG 4. Fatty Acid Methyl Ester (FAME) 5. MAG 6. FAME 7. FAME 8. MAG 9. FAME 0. Di-acylglycerol (DAG). Tri-acylglycerol (TAG) Column: Alltech Alltima HP C8 HiLoad, 5µm, 50 x 4.6mm, (Part No. 87698) Mobile Phase: A: Acetonitrile B: Dichloromethane Gradient: Time: 0 5 0 5 %B: 0 5 70 70 0 Flow Rate:.0 ml/min 4 5 6 Robitussin Flu Syrup 0 5 0 5 0 5 0 5 40 Min. Column: Alltech Prevail Carbohydrate ES, 5µm, 50 x 4.6mm, (Part No. 50) Mobile Phase: A: Acetonitrile B: Water Gradient: Time: 0 5 0 5 5 %B: 5 5 5 5 50 Flow Rate:.0 ml/min 0557. Sucralose. Fructose. Sorbitol 4. Glucose 5. Sucrose 6. Maltose
Ordering Information Description Alltech 00 ELSD* Part No. 00 ELSD 0V 40V 0000 *Patent Pending Description Services for the Alltech 00 ELSD Part No. Installation and Training INSTALL Qualification IQ/OQ at Customer Site Q000 PQ at Customer Site Q000 IQ/OQ/PQ at Customer Site Q000 Alltech의뛰어난 application chemists와기술지원전문가들은방대한 technical library를끊임없이추가하고있다. www.elsd.com을방문하여응용자료를검색하거나, application 또는아래의응용예문들을다운로드하시기바랍니다. Lipids Carbohydrates Pharmaceuticals Alltech 00 ELSD Specifications Light Source: Laser diode with collimating optics, 650nm, 0mW output, class IIIB Detector Element: Silicon photodiode Temperature Range: Ambient to 0ºC in ºC increments Nebulizer Gas: Nitrogen preferred; Calibrated to 4.0L/ min Inlet Pressure: 60 80psig Typical Operating Range:.0.0L/min Flow Control: Digital Mass Flow Control Mobile Phase Flow Rate: To.0mL/min Analog Output: V or 0mV full scale Communications: Inputs: TTL/contact closure for auto zero, gas shutoff, start, and standby Outputs: Contact Closure for pump shutdown in error conditions, general events Data Ports: USB, RS, Ethernet User Interface: Full color Microsoft Windows based Graphical LCD with alphanumeric keypad Power Requirements: 0/40V, 50/60Hz Dimensions:.6" H x 0." W x 9.5" D (9.5cm H x 6.cm W x 49.5cm D) Weight: 0lbs (6Kg) IEC/FDA Classification: Class Laser Product; Complies with CFR Subpart J Manufacturing Standards: Meets all applicable safety and EMC certifications; CE, UL, and CSA certified Warranty: year parts and labor See how the 00 ELSD can benefit your analysis! Visit and click on "Contacts". Ask about sample analysis or a product demonstration in your lab. ALLTECH, ALLTIMA, DENALI, FLEXIT, GROM, JONES CHROMATOGRAPHY, MODCOL, PLATINUM, PREVAIL, PROSPHERE, and VYDAC are trademarks, registered in the United States and/or other countries, of Alltech Associates, Inc. DAVISIL, GRACE and GRACE DAVISON DISCOVERY SCIENCES are trademarks, registered in the United States and/or other countries, of W. R. Grace & Co.-Conn. MICROSOFT WINDOWS and WINDOWS are trademarks, registered in the United States and/or other countries, of Microsoft Corporation. ROBITUSSIN is a trademark, registered in the United States and/or other countries, of American Home Products Corp. This trademark list has been compiled using available published information as of the publication date of this brochure and may not accurately reflect current trademark ownership. Grace Davison Discovery Sciences is a product group of W. R. Grace & Co.-Conn. Alltech Associates, Inc. is a wholly owned subsidiary of W. R. Grace & Co.-Conn. Copyright 006 Alltech Associates, Inc. All rights reserved. The information presented herein is derived from our testing and experience. It is offered, free of charge, for your consideration, investigation and verification. Since operating conditions vary significantly, and since they are not under our control, we disclaim any and all warranties on the results which might be obtained from the use of our products. You should make no assumption that all safety or environmental protection measures are indicated or that other measures may not be required. This product(s) may be covered by patents or patents pending. Grace reserves the right to change prices and/or specifications without prior notification. Printed in the USA. 09/06 #5 Grace Davison Discovery Sciences