Medical POSTGRADUATES No. 6, Vol.31, 2003 A Case of Colonoscopic Reduction of Sigmoid Volvulus Fig. 3 Fig. 4 Fig. 5 Fig. 1 Fig

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1 Medical POSTGRADUATES Abstracts

2 Medical POSTGRADUATES No. 6, Vol.31, 2003 A Case of Colonoscopic Reduction of Sigmoid Volvulus Fig. 3 Fig. 4 Fig. 5 Fig. 1 Fig

3 (a) (a) (b) (b) Fig. 1. Simple Abdomen Findings. Simple abdomen shows -shaped distended colon without rectal gas[(a)supine view (b)erect view] (c) Fig. 2. Abdominal CT scans. CT scans show dilated bowel loop emerging from the pelvis and extending to the upper abdomen(a), (b), (c) 302

4 (a) Fig. 4. F/U Simple Abdomen. The distended bowel loop disappeared after the endoscopic reduction. (b) (c) Fig. 3. Emergency colonoscopic findings. Dilated lumen with large amount feces and gas is noted in sigmoid colon(a), (b). Clock-wise twisted mucosal fold is noted at the site of volvulus(c) 303

5 (a) (b) (c) Fig. 5. F/U Colonoscopic findings. There were no specific lesions in the colon(a), (b), (c) 304

6 Medical POSTGRADUATES No. 6, Vol.31, 2003 Emerging Viral Diseases (Fig. 1A) (Fig. 1) Fig

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17 Table 2 Table 2 Fig. 1 Table 1 Fig. 1. Table % < 30% 70-80% 95% > 70% 2-15%, (HUS/TTP) 10-15% 20% Table

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20 REFERENCES 1. (2003) :, 14(7) : Mead PS, Griffin PM (1998) : Escherichia coli O157:H7. L a n c e t, 352 : Su C, Brandt LJ (1995) : Escherichia coli O 157 : H 7 infections in humans. Ann Intern Med, 123 : Boyce TG, Swerdlow DL, Griffin PM (1995) : Current concepts : Escherichia coli O157:H7 and the hemolytic-uremic syndrome. N Engl J Med, 333 : , 9 6. Todd WTA, Dundas S (2001) : The management of VTEC O157 infection. Internat J Food Microbiol, 6 6 : Centers for Disease Control and Prevention. (2002) : Preliminary FoodNet data on the incidence of foodborne illness-selected sites, United States. M M W R, 52 : Fey PD, Wickert RS, Rupp ME, Safranek TJ, Hinrichs SH (2000) : Prevalence of non-ol57:h7 Shiga toxinproducing Escherichia coli in diarrheal stool samples from Nebraska. Emerg Infect Dis, 6 : Nataro JP, Kaper JB (1998) : Diarrheagenic Escherichia coli. CIin Microbiol Rev, 1 : O'Brien AD, LaVeck GD, Thomson MR, Formal SB (1982) : Production of Shigella dysenteriae type l-like cytotoxin by Escherichia coli. J Infect Dis, 146 : Proulx F, Turgeon JP, De1age G, Lafleur L, Chicoine L (1992) : Randomized controlled trial of antibiotic therapy for Escherichia coli O157:H7 enteritis. J P e d i a t r, 121 : (2003) : Riley LW, Remis RS, Helgerson SD, McGee HB, Wells JG, Davis BR, Hebert RJ, Olcott ES, Johnson LM, Hargrett NT, Blake PA, Cohen ML (1983) : Hemorrhagic colitis associated with a rare Escherichia coli serotypes. N Engl J Med, 308 : Safdar N, Said A, Gangnon RE, Maki DG (2002) : Risk of hemolytic uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 enteritis. A Meta-analysis. J A M A, 288 : Wong CS, Jelacic S, Habeeb RL, Watkin SL, Tarr PI (2000) : The risk of the hemolytic uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 Infections. N Engl J Med, 342 : 1930-I

22 Medical POSTGRADUATES No. 6, Vol.31, 2003 Reemerging Plasmodium vivax Malaria in the Republic of Korea (Table 1, Fig. 1) Table

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26 325 (Table 1, Fig. 1) Table 2 Table 2.

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29 328 (Table 1) (Table 2) Medical POSTGRADUATES No. 6, Vol. 31, 2003 Bioterrorism

30 Table 1. Bacillus anthracis Smallpox Yersinia pestis Viral hemorrhagic fever Francisella tularensis Salmonella typhi Shigella species Coxiella burnetii Brucella suis Vibrio cholera Botulinum Staphylococcal enterotoxin B Diphtheria toxin Snake toxin Rice blast Rye stem rust Table 2. Category A Category B Category C Bacillus anthracis Coxiella burnetti Nipah virus variola major(smallpox) Brucella species Multi-drug resistant tuberculosis Yersinia pestis(plague) Burkholderia mallei Yellow fever virus - Flaviviridae - Venezuelan encephalomyelitis - Ebola hemorrhagic fever - eastern and western - Marburg hemorrhagic fever equine encephalomyelitis - Arenaviridae - Lassa fever - Argentine hemorrhagic fever Clostridium botulinum toxin Francisella tularensis ricin toxin epsilon toxin staphylococcal enterotoxin B Salmonella species Shigella dysenteriae Escherichia coli O157:H7 Vibrio cholera Cryptosporidium parvum 329

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granulatus 29 4 HN-6, HN-7, HN-8, HN-9 HNM-11, HNM-12, HNM-13 mouse A.

37 Table 1. Province Source Species No. of tested No. of culture Isolate Choongbuk tick* I. nipponensis 8 3 KK-1, KK-2, KK-5 mouse A. agrarius 12 2 KM-4, KM-10 Choonnam tick I. granulatus 29 4 HN-6, HN-7, HN-8, HN-9 HNM-11, HNM-12, HNM-13 mouse A. agrarius 20 9 HNM-14, HNM-15, HNM-16 Kangwon tick* I. persulcatus 16 1 KW-3 Kyungbuk tick* Ixodes sp. 9 0 Cheju tick* Haemaphysalis sp * Collected by flagging vegetation HNM-17, HNM-18, HNM-19 Fig. 2, 3, 4 Fig

38 Fig. 1, 2 Fig. 2 Fig. 3 Fig. 4 Fig

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40 Medical POSTGRADUATES No. 6, Vol.31, 2003 Madcow Disease and Other Prion Diseases Table 1. Scrapie Table 1 Transmissible mink encephalopathy Chronic wasting disease Bovine spongiform encephalopathy Feline spongiform encephalopathy,,,,,, 339

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42 Table 2 Table 2. CJD CJD (yr) (mo) 5 14,,, 40% 94% 100% 0% 10% 100% Codon 129 MM subtype 80% 100% 341

43 Table 3 Table 3. Kuru (cannibalism) CJD sporadic CJD? (somatic mutation?) iatrogenic CJD CJD (,, ) familial CJD PrP mutation (codon 178,180,200,232) new variant CJD BSE? Gerstmann-Straussler-Scheinker disease PrP mutation (codon 102,105,117,198,217) Fatal familial insomnia PrP mutation (codon 178, 200) 342

44 REFERENCES 1. Haywood AM (1997) : Transmissible spongiform encephalopathies. N Engl J Med, 337 : Prusiner SB (1997) : Prion diseases and the BSE crisis. S c i e n c e, 278 : Gajdusek DC, Zigas V (1957) : Degenerative disease of the central nervous system in New Guinea : The endemic occurrence of kuru in the native population. N Engl J Med, 257 : Gajdusek DC, Gibbs CJ, Alpers M (1966) : Experimental transmission of a kuru-like syndrome to chimpanzees. N a t u r e, 209 : Gibbs CJ Jr, Gajdusek DC, Asher DM et al. (1968) : Creutzfeldt-Jakob disease (spongiform encephalopathy) : Transmission to the chimpanzee. S c i e n c e, 161 : Prusiner SB, Groth D, Serban A et al. (1993) : Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-prp antibodies. P r o c Natl Acad Sci U S A, 90 : Ricketts MN, Cashman NR, Stratton EE, El Saadany S (1997) : Is Creutzfeldt-Jakob disease transmitted in 343

45 blood? Emerg Infect Dis, 3 : Klein R, Dumble LJ (1993) : Transmission of Creutzfeldt-Jakob disease by blood transfusion. L a n c e t, 341 : Creange A, Gray F, Cesaro P et al. (1995) : Creutzfeldt- Jakob disease after liver transplantation. Ann Neurol, 38 : Manuelidis EE, Kim JH, Mericangas JR, Manuelidis L (1985) : Transmission to animals of Creutzfeldt-Jakob disease from human blood. L a n c e t, 2 : Tateishi J (1985) : Transmission of Creutzfeldt-Jakob disease from human blood and urine into mice. L a n c e t, 2 : Zerr I, Bodemer M, Gefeller O et al. (1998) : Detection of protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease. Ann Neurol, 43 : Johnson RT, Gibbs Jr C (1998) : Creutzfeldt-Jakob disease and related transmissible spongiform encephalopathies. N Engl J Med, 339 :

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53 Medical POSTGRADUATES No. 6, Vol.31, 2003 Abstracts Use of a Whole Blood Rapid Panel Test for Heart-Type Fatty Acid- Binding Protein in Patients with Acute Chest Pain : Comparison with Rapid Troponin T and Myoglobin Tests Yoshihiko Seino et al. P l a t e l e tendothelial Biomarkers in Depressed Patients Treated Am J Med, 115 : , 2003 with the Selective Serotonin Reuptake Inhibitor Sertraline after Acute Coronary Events. The Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy Victor L Serebruany et al. Circulation, 108 : ,

54 Effects of Candesartan on Mortality and Morbidity in Patients with Chronic Heart Failure : the CHARM-Overall Programme Marc A Pfeffer et al. Antioxidant Vitamins C and E Improve Endothelial Function in Children with Lancet, 362 : , 2003 Hyperlipidemia. Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial Marguerite M Engler et al. Circulation, 108 : ,

55 Safety of an Aspirin-Alone Regimen after Intracoronary Stenting with a Heparin-Coated Stent. Final Results of the HOPE (HEPACOAT and an Antithrombotic Regimen of Aspirin Alone) Study Roxana Mehran et al. Circulation, 108 : , 2003 L1 Expression as a Predictor of Progression and Survival in Patients with Uterine and Ovarian Carcinomas Mina Fogel et al. Lancet, 362 : , 2003 Recreational Physical Activity and the Risk of Breast Cancer in Postmenopausal Women Anne Mectiernan et al. JAMA, 290 : ,

56 Parvovirus B19 Infection Mimicking Acute Myocardial Infarction Uwe Kuhl Circulation, 108 : ,

57 Medical POSTGRADUATES No. 6, Vol. 31, 2003

(1-5장)바이오백서8.6-최종

(1-5장)바이오백서8.6-최종 Biosafety white paper 2011 Ministry of Knowledge Economy Korea Research Institute of Bioscience and Biotechnology www.kribb.re.kr issue issue 2011 Biosafety white paper issue 2011 Biosafety white paper