지원연구분야 ( 코드 ) LC0202 과제번호 창의과제프로그램공개가능여부과제성격 ( 기초, 응용, 개발 ) 응용실용화대상여부실용화공개 ( 공개, 비공개 ) ( 국문 ) 연구과제명 과제책임자 세부과제 ( 영문 ) 구분 소속위암연구과직위책임연구원

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지원연구분야 ( 코드 ) LC0202 과제번호 1110550 창의과제프로그램공개가능여부과제성격 ( 기초, 응용, 개발 ) 응용실용화대상여부실용화공개 ( 공개, 비공개 ) ( 국문 ) 연구과제명 과제책임자 세부과제 ( 영문 ) 구분 1 2 3 소속위암연구과직위책임연구원 성명류근원전공외과 세부과제명 세부과제책임자 성명 소속 ( 직위 ) 전공 총연구기간 2011 년 2 월 ~ 2013 년 12 월 ( 총 3 년 ) 참여연구원수 ( 단위 : 명, MY) 34 연구기간및 연구비 ( 단위 : 천원 ) 구분연구기간계 국립암센터 계 2011.2~2013.12 250,000 250,000 제 1 차 2011.2~2011.12 50,000 50,000 제 2 차 2012.1~2012.12 100,000 100,000 제 3 차 2013.1~2013.12 100,000 100,000 참여기업명칭전화 FAX 기업부담금소계현금현물 기관고유연구사업관리규칙에따라본연구개발사업을성실히수행하였으며아래와같이최종보고서 를제출합니다. 2013 년 10 월 30 일 과제책임자 ( 서명 )

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연구목표 (200 자이내 ) 연구내용및방법 (500 자이내 ) 연구개발에따른기대성과 < 최종목표 > < 당해연도목표 >

조기위암감시림프절생검위보존수술 국문 색인어 영문 early gastric cancer sentinel node biopsy stomach surgery preserving

Is the new seventh AJCC/UICC staging system appropriate for patients with gastric cancer? 2012;214(1):8 8-96 2012;99(3):39 7-403 2012;12(1):1-2. 2013;2(3):160-163 2013;27(9):32 47-3253

Is the new 7 th UICC/AJCC staging system appropriate for patients with gastric cancer? Oncologic effectiveness of regular follow-up to detect recurrence fater the curative resection of gastric cancer. Comparison of surgical performances and short-term clinical outcomes between laparoscopic and robotic surgery in gastric cancer. Biopathologic features and clinical significance of micrometastasis in the lymph node of early gastric cancer. The risk factors for lymph node metastasis in early gastric cancer patients who underwent endoscopic resection: Is the minimal lymph node dissection applicable? Proposal of the surgical options for primary tumor control during sentinel node navigation surgery based on the discrepancy between preoperative early gastric cancer diagnosis. 9 th InternationalGastric CancerCongress 9 th InternationalGastric CancerCongress. 20 th InternationalCongr essoftheeuropeanass ociationforendoscopic Surgery 10 th InternationalGastri ccancercongress 10 th InternationalGastri ccancercongress 10 th InternationalGastri ccancercongress

Laparoscopic Gastectomy Keun Won Springer, 2012 101-10 Role of Robotic for Cancer Standard Ryu, Woo 4 Surgery for Techniques and Clinical Jin Hyung, Laparoscopy-Assisted Evidences. N o b u h i k o Distal Gastrectomy. Tanigawa, Sang-Woon g Lee. Laparoscopic Gastectomy H i r o k a z u Springer, 2012 163-16 Training Systems and for Cancer Standard Yamaguchi, 4. the Learning Curve. In Techniques and Clinical M i c h i o L a p a r o s c o p i c Evidences. Kaminishi, Gastectomy for Cancer a n d Standard KeunWonR Techniques and yu. Clinical Evidences.

1. Ryu KW, Eom BW, Nam BH, Lee JH, Kook MC, Choi IJ, Kim YW. Is the sentinel node biopsy clinically applicable for limited lymphadenectomy and modified gastric resection in gastric cancer? A meta-analysis of feasibility studies. J Surg Oncol. 2011 Nov 1;104(6):578-84.

2. Lee JH, Ryu KW, Lee SE, Cho SJ, Lee JY, Kim CG, Choi IJ, Kook MC, Kim MJ, Park SR, Lee JS, Nam BH, Kim YW. Learning curve for identification of sentinel lymph node based on a cumulative sum analysis in gastric cancer. Dig Surg. 2009 Feb;26(6):465-70. 3. Lee SE, Lee JH, Ryu KW, Cho SJ, Lee JY, Kim CG, Choi IJ, Kook MC, Nam BH, Park SR, Lee JS, Kim YW. Sentinel node mapping and skip metastases in patients with early gastric cancer. Ann Surg Oncol. 2009 Mar;16(3):603-8. 4. Lee JH, Ryu KW, Nam BH, Kook MC, Cho SJ, Lee JY, Kim CG, Choi IJ, Park SR, Kim YW. Factors associated with detection failure and false-negative sentinel node biopsy findings in gastric cancer: results of prospective single center trials. J Surg Oncol. 2009 Mar 1;99(3):137-42. 5. Lee JH, Ryu KW, Kook MC, Lee JY, Kim CG, Choi IJ, Kim SK, Jang S, Park SR, Kim YW, Nam BH, Bae JM. Feasibility of laparoscopic sentinel basin dissection for limited resection in early gastric cancer. J Surg Oncol. 2008 Oct 1;98(5):331-5. 6. Lee JH, Ryu KW, Kim CG, Kim SK, Lee JS, Kook MC, Choi IJ, Kim YW, Chang HJ, Bae JM. Sentinel node biopsy using dye and isotope double tracers in early gastric cancer. Ann Surg Oncol. 2006 Sep;13(9):1168-74. 7. Lee JH, Ryu KW, Kim CG, Kim SK, Choi IJ, Kim YW, Chang HJ, Bae JM, Hong EK. Comparative study of the subserosal versus submucosal dye injection method for sentinel node biopsy in gastric cancer. Eur J Surg Oncol. 2005 Nov;31(9):965-8. 8. Ryu KW, Lee JH, Kim HS, Kim YW, Choi IJ, Bae JM. Prediction of lymph nodes metastasis by sentinel node biopsy in gastric cancer. Eur J Surg Oncol. 2003 Dec;29(10):895-9. 1. Yoon HM, Ryu KW, Nam BH, Cho SJ, Park SR, Lee JY, Lee JH, Kook MC, Choi IJ, Kim YW.Is the new seventh AJCC/UICC staging system appropriate for patients with gastric cancer? J Am Coll Surg. 2012 Jan;214(1):88-96. 2. Lee SD, Ryu KW, Eom BW, Lee JH, Kook MC, Kim YW. Prognostic significance of peritoneal washing cytology in patients with gastric cancer. Br J Surg. 2012

Mar;99(3):397-403. 3. Ryu KW. The future of sentinel node oriented tailored approach in patients with early gastric cancer. J Gastric Cancer. 2012 Mar;12(1):1-2. 4. Son SY, Park JY, Ryu KW, Eom BW, Yoon HM, Cho SJ, Lee JY, Kim CG, Lee JH, Kook MC, Choi IJ, Kim YW.. The risk factors for lymph node metastasis in early gastric cancer patients who underwent endoscopic resection: is the minimal lymph node dissection applicable? A retrospective study. Surg Endosc. 2013 Sep;27(9):3247-53. 5. Woo JW, Ryu KW, Park JY, Eom BW, Kim MJ, Yoon HM, Park SR, Kook MC, Choi IJ, Kim YW, Park YI. Prognostic Impact of Microscopic Tumor Involved Resection Margin in Advanced Gastric Cancer Patients after Gastric Resection. World J Surg. 2013 Oct 17. [Epub ahead of print] 6. Ryu KW, SENORITA study group. Future perspective of laparoscopic surgery for gastric cancer: Sentinel node navigation function-preserving surgery for early gastric cancer. Transl Gastrointest Cancer 2013;2(3):160-163