Table 1. Distribution by site and stage of laryngeal cancer Supraglottic Glottic Transglottic Total Stage Total 20

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1 KISEP Head and Neck Korean J Otolaryngol 1999;42: 후두암수술환자에대한치료성적 송달원 김희준 정현수 김영한 안재현 이복수 박선호 Treatment Result in Laryngeal Cancer Patients Submitted to Surgical Treatment Dal Won Song, MD, Hee Jun Kim, MD, Hyun Soo Jeong, MD, Young Han Kim, MD, Jae Hyun Ahn, MD, Bok Su Lee, MD and Sun Ho Park, MD Department of Otolaryngology, School of Medicine, Keimyung University, Taegu, Korea ABSTRACT Background and ObjectivesLaryngeal cancer is the most common malignant tumor within head and neck and is known for having a good prognosis in comparison to the other malignancies. The surgery to the larynx and neck is one of the prime treatment modality for the laryngeal cancer. The purpose of this study is to review the surgical experience of our hospital and to focus on the results of the surgical treatment of the laryngeal cancer. Materials and MethodsAnalyzed 41 laryngeal cancer patients who underwent surgery during the period of 5 years from January 1989 to December TNM staging of the disease was done by the AJCC staging system issued in The 5-year survival rate was calculated by Kaplan-Meier method. Results1 The overall 5-year survival rate was 65.8%. 2 The 5-year survival rate according to clinical stage showed 100%, 83.3%, 76.9%, and 50% in stage,,, respectively. 3 The 5-year survival rate according to T stage showed 75%, 66.7%, 57.9%, 77.8%, in T1, T2, T3, T4 respectively. 4 The 5-year survival rate according to nodal status showed N 78.9%, N 56.2%. 5 The 5-year survival rate according to primary site showed supraglottis 60%, glottis 100%, transglottis 57.1%. 6 The 5-year survival rate according to treatment modalities showed surgery only patients 80%, postoperative radiation patients 60%, salvage operation patients 54.6%. ConclusionEarly stage, glottic cancer and the patients who only had operation showed good treatment result. Regional lymph node metastasis, at the time of diagnosis, was found to carry a worse prognosis. The main cause of treatment failure was distant metastasis. Korean J Otolaryngol 1999;42: KEY WORDSLaryngeal cancer Surgery. 1284

2 Table 1. Distribution by site and stage of laryngeal cancer Supraglottic Glottic Transglottic Total Stage Total Table 2. Distribution of cases by TN stage and site N0 N1 N2 N3 Total Supragottic T T T T Total Glottic T1 1 1 T2 4 4 T3 1 1 T4 1 1 Total Transglottic T T T Total Table 3. Method of surgical treatment according to T-stage T-stage Surgical modalities T1 T2 T3 T4 Total Supraglottic cancer Total laryngectomy Supraglottic laryngectomy Extended supraglottic laryngectomy 2 2 Glottic cancer Total laryngectomy Hemilaryngectomy Transglottic cancer Total laryngectomy Hemilaryngectomy 1 1 Total

3 Fig. 1. Overall 5-year survival curve. Table 4. Methods of surgical treatment according to N stage Bilateral Unilateral MRND SND RND/MRND RND MRND SND Supraglottic N0 3 4 N1 2 4 N N3 1 Glottic N0 4 N1 1 N2 N3 Transglottic N N1 2 N N3 Total false positive60.7%, false negative1.9% Fig year survival curve by stage. Table 5. Postoperative complication and site of failure Complication No. Pharyngocutaneous fistula 7 Stomal stenosis 5 Dysphagia 3 Laryngeal stenosis 2 Carotid artery rupture 1 Wound disruption 1 Site of failure Primary site 1 Neck 5 Distant metastasis 8 Fig year survival curve by T stage Korean J Otolaryngol 1999;42:1284-9

4 Fig year survival curve by nodal state. Fig year survival curve by Site. Fig year survival curve by treatment modalities. 1287

5 1288 Korean J Otolaryngol 1999;42:1284-9

6 REFERENCES 1) Kim KH, Park CI. Clinical study on laryngeal cancer: evaluation of treatment result. KoreanJ Otolaryngol ) Lee SY, Choi JW, Jung KY, Yoo HK. The results of conservation surgery in laryngeal cancer. Kor J Head and Neck Oncol ) Johnson JT, Myers EN, Hao SP, Wagner RL. Outcome of open surgical therapy for glottic carcinoma. Ann Otol Rhinol Laryngol ) Berger G, Peter van Nostrand AW. Failure analysis of T1 glottic carcinoma treated with radical radiotherapy for cure with surgery in reserve. In Chertien, Johns, Shedd, Strong, Ward. editors. Head and neck cancer. St. Louis Mosby1985. p ) Liggett. WH Jr, Forastiere AA. Chemotherapy for Head and Neck Cancer. In: Cummings CW, Fredrickson JM, Harker LA, Krause CJ, Richardson MA, Schuller DE, Editors Otolaryngology-Head and Neck Surgery. 3rd ed. St. Louis Mosby Year Book1996. p ) Reddy KTV, Vinayak BC, Jefferis AF, Wallace M. Primary radiotherapy for treating all laryngeal cancer a district hospital experience. J. Laryngol. Otol ) Kim DJ, Song DW. Faiure analysis of radical radiotherapy in laryngeal cancer. Korean J Otolaryngol ) Shim YS, Yoo SY. Treatment result of the carcinoma of the larynx. Korean J Otolaryngol ) Kim KH, Noh KT, Sung MW, Baek CH, Yoo YS. Treatment result of laryngeal cancer. Korean J Otolaryngol ) Suarez C, Llorente JL. Neck dissection with or without postoperative radiotherapy in supraglottic carcinoma. Head. Neck. Surg ) Zanaret M, Giovanni A, Gras R, Cannoni M. Near total laryngectomy with epiglottic reconstruction long-term results in 57 patients. Am J Otolaryngol ) Moon KG, Tae K, Kim KR, Lee HS, Ahn KS. Treatment result of laryngeal cancer. Korean J Otolaryngol ) Thawley SE. Complication of combined radiation therapy and surgery for carcinoma of the larynx and inferior hypopharynx. Laryngoscope ) Choi EC, Cho CH, Lee SM, Kim YH, Hong WP. Pharyngocutaneous fistula after total laryngectomy. Korean J Otolaryngol ) Shim YS, Oh KK, Yoon IH, Jun JB. Surgical salvage after radiation for laryngeal cancer. Korean J Otolaryngol ) Kim KH, Kim HJ, Juhn SH, Lee SI. A clinical study on the surgery of laryngeal cancer. Korean J Otolaryngol ) Kim BS, Park JS, Kim SH, Kwon TH, Seong CS. Clinical analysis of locoregional recurrence after total laryngectomy for laryngeal cancer. Korean J Otolaryngol

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( )Jkstro011.hwp 비인강암의방사선치료결과및생존율에관한예후인자분석 2005 2 1 2005 3 28. :, Tel: 053)250-7665, Fax: 053)250-7984 E-mail: jhkim@dsmc.or.kr 정영연외 2 인 : 비인강암의예후인자분석 정영연외 2 인 : 비인강암의예후인자분석 Carcinoma of the nasopharynx treated by radiotherapy