충북의대학술지 Chungbuk Med. J. Vol. 27. No. 1. 1~ Charcot-Marie-Tooth Disease 환자의마취 : 증례보고 신일동 1, 이진희 1, 박상희 1,2 * 책임저자 : 박상희, 충북청주시서원구충대로 1 번지, 충북대학교

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1 충북의대학술지 Chungbuk Med. J. Vol. 27. No. 1. 1~ Charcot-Marie-Tooth Disease 환자의마취 : 증례보고 신일동 1, 이진희 1, 박상희 1,2 * 책임저자 : 박상희, 충북청주시서원구충대로 1 번지, 충북대학교의과대학마취통증의학교실, 의학연구소 (28644), happycat19@hanmail.net (Tel: , Fax: ) - 1 -

2 Il-Dong Shin, Jin-Hee Lee, Sang-Hi Park μ - 2 -

3 Anesthesia of Charcot-Marie-Tooth disease patient 1. Vallat JM, Mathis S, Funalot B. The various Charcot-Marie-Tooth diseases. Curr Opin Neurol 2013;26: Hines L, Marschall KE. Anesthesia & Co-existing disease 5th ed.; 2008, p Fleisher LA. Anesthesia and Uncommon disease. 6th ed. Philadelphia(PA):Elsevier Inc.;2012. p Vinci P, Lapi G. Anesthetic management in Charcot-Marie-Tooth disease type 2 due to a mutation in the mitofusin-2 gene. J Anesthesiol Clin Pharmacol. 2011; 27: Stoelting RK, Dierdorf SF. Anesthesia and co-existing disease. 4th ed. New York(NY): Churchill Livingstone; p Hanich RF, Levine JH, Spear JF, Moore EN

4 Il-Dong Shin, Jin-Hee Lee, Sang-Hi Park Autonomic modulation of ventricular arrhythmia in cesium chloride-induced long QT syndrome. Circulation 1988; 77: Sharpe MD, Dobkowski WB, Murkin JM, Klein G, Yee R. Propofol has no direct effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia. Anesthesiology. 1995;82: Kotani N, Hirota K, Anzawa N, Takamura K, Sakai T, Matsuki A. Motor and sensory disability has a strong relationship to induction dose of thiopental in patients with the hypertrophic variety of Charcot-Marie-Tooth syndrome. Anesth Analg 1996;82: Pogson D, Telfer J, Wimbush S. Prolonged vecuronium neuromuscular blockade associated with Charcot-Marie-Tooth neuropathy. Br J Anaesth 2000;85: Antognini JF. Anaesthesia for Charcot-Marie-Tooth disease: a review of 86 cases. Can J Anaesth 1992;39:

5 Anesthesia of Charcot-Marie-Tooth disease patient Anesthesia of a Patient with Charcot-Marie-Tooth Disease: a Case Report Il-Dong Shin 1, Jin-Hee Lee 1, Sang-Hi Park 1,2 Department of Anesthesiology and Pain Medicine, Chungbuk National University Hospital 1, Department of Anesthesiology and Pain Medicine, College of Medicine and Medical Research Institute, Chungbuk National University 2 Recently, as the surgical treatment of patients with Charcot-Marie-Tooth disease has increased, the importance of perioperative anesthesia management for Charcot-Marie-Tooth patients has also been growing. Patients with Charcot-Marie-Tooth disease are characterized by inherited neuropathy and have a high incidence of lower extremity atrophy and are often accompanied by respiratory failure. Inhalation anesthetic agents for anesthesia increase the incidence of malignant hyperthermia and slow recovery of muscle relaxants. In addition, when using analgesic opioids, respiratory failure occurs more often than usual. We report a case of a 60 year old woman who underwent total intravenous anesthesia for the correction of the left humerus fracture. * Corresponding Author: Sang-Hi Park, Department of Anesthesiology and Pain Medicine, Chungbuk National University Hospital, Department of Anesthesiology and Pain Medicine, College of Medicine and Medical Research Institute, Chungbuk National University, 776, 1 Sunhwan-ro, Seowon-Gu, Cheongju, Chungbuk, 28644, Korea. happycat19@hanmail.net(tel: ,fax: ) - 5 -

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