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Comparison of Laparoscopy and Exploration in the Distal Pancreatectomy BACKGROUND: To determine the benefits of laparoscopic surgery compared with exploration, the clinical outcomes of open and laparoscopic distal pancreatectomy were compared. METHOD: From March 2005 to June2007, we studied 95 patients at Asan Medical Center. These patients had benign pancreatic disease in the distal pancreas, e.g. a cystic neoplasm. These patients underwent a distal pancreatectomy with or without spleen-preservation using laparoscopic or exploration surgery. We divided these patients into two groups i.e. laparoscopy (n=60) and exploration (n=35), and compared the outcomes of the two groups retrospectively. RESULT: There was no difference in demographic features between the two groups. Laparoscopic resection required a median time of 208 mins, compared with 190 mins for the open resection. (p>0.05) The laparoscopic patients started a liquiddiet on postoperative day three, and required a median hospital stay of 11 days, compared with 4.5 days and 16 days for the open resection surgery, respectively. (p<0.001) The overall postoperative complication rate was 28.3% for the laparoscopic group compared with 22.9% for the open group. (p>0.05) The pancreatic fistula rate was lower in the laparoscopic patient group than in the open group. (8.3% vs. 14.3%) (p>0.05) The rate of spleen-preservation was higher in the laparoscopy group than the open group. (25% vs. 5.7%), (p>0.05) CONCLUSION: The results of this study showed that the laparoscopic distal pancreatectomy had a similar surgical time, an early start of the diet, a shorter hospital stay, and a higher spleensaving rate, compared to exploration surgery. Therefore, considering the benefits of laparoscopic surgery, it appears to be the preferred approach, with or without spleen-preservation, for treating benign distal pancreatic disease.

Current status of laparoscopic surgery of the pancreas. J Hepatobiliary Pancreas Surg 1999; 6: 154-164. Con La telecamera dove sembra impossibile. Osp Ital Chir. 2000; 6: 331-332 Peritoneoscopy and pancreas biopsy in the diagnosis of pancreatic disease. Gastrointest Endosc 1983; 29:211-218 Early experience with laparoscopic resections of islet cell tumor. Surg 1996; 120: 1051-1054. Is laparoscopic left pancreatic resection justified Surg Endosc 2002; 16: 1358-61. Laparoscopic spleen-preserving distal pancreatectomy. J Gastrointest Surg. 2005; 9: 733-738 Laparoscopic distal pancreatectomy with preservation of the spleen and splenic vessels for benign Pancreas neoplasm. Surg Endosc. 2005; 19: 1367-1369 Laparoscopic distal pancreatectomy combined with preservation of the spleen for cystic neopla of the pancreas. J Gastrointest Surg 2004; 8: 493-501 Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy results of a prospective randomized trial. Surgery 2003; 134: 766-71 The potent somatostatin analogue vapreotide does not decrease pancreas-specific complications after elective pancreatectomy: a prospective, multicenter, double-blinded, randomized, placebo-controlled trial. J Am Coll Surg. 2003; 196: 556-64 Distal pancreas surgery: outcome for 19 cases managed with a laparoscopic approach. Surg Endosc 2006; 20: 1729-1732 Laparoscopic pancreatic cystogastrostomy: the first operation in the new field of intraluminal laparoscopic surgery. Surg Endosc 1994; 8:235-239 Intraluminal stapled laparoscopic cystogastrostomy for the treatment of pancreatic pseudocyst. Br J Surg 1995; 82:403 Laparoscopic distal pancreatectomy: a comparative study. Hepatogastroenterology. 2007; 54:265-271 Laparoscopic enucleation of a pancreatic mucinous cysdadenoma. J Korean Surg Soc 2005; 68: 181-185 Laparoscopic cystogastrostomy for the patient of pancreatic pseudocyst with intraabdominal adhesion. J Korean Surg Soc 2007; 73:83-86 Laparoscopic cystogastrostomy in pancreatic pseudocysts. J Korean Surg Soc 2000; 59: 699-702 Laparoscopic spleen preserving distal pancreatectomy with the conservation of the splenic artery and the vein. J Korean Surg Soc 2003; 64: 521-525 Outcome of laparoscopic pancreatic surgery: endocrine and nonendocrine tumours. World J Surg 2002; 26: 1057-1065

Laparoscopic pancreatic resection: single-institution experience of 19 patients. J Am Coll Surg 2001; 193: 1281-287 Distal pancreatectomy: does the method of closure influence fistula formation Am Surg 2002; 68: 267-268 Laparoscopic distal pancreatectomy: Results on a Consecutive Series of 58 patients. Ann Surg. 2007; 246: 77-82 Conservation of the spleen with distal pancreatectomy. Arch Surg 1988; 123: 550-553 Case-control comparison of laparoscopic versus open distal pancreatectomy. J Gastrointest Surg 2007; 10:95-98