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1 임상연구계획 및논문작성의실제 I Investigators/Collaborators: Jeong-Yeol Park Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
2 임상연구논문작성의이유? 진급을위해서 학위를받기위해서 연구비수혜를위해서 기타 하라고시키니까 안하면안되니까 등등 Significance 과학적질문에대한해답을찾기위해서 의미있는발견을다른연구자들과공유하기위해 다른연구자들의연구에도움이되는발견을공유하기위해 논문을위한논문 의미있는논문
3 임상연구논문작성과정 연구주제결정 연구의수행 후향적연구전향적연구 Meta-analysis 논문작성 논문제출 Reject 논문의 revision 논문의출간
4 연구주제의결정 고찰을통해얻어진통찰력 많은임상경험 체계적인문헌고찰 Originality Novelty Me too study Time-dependent ( 시간싸움 )
5 연구의수행 연구계획서작성및 IRB 승인 (ethic approval) 후향적연구 Data collection from medical records 전향적연구 Phase I, II, III trial Prospective observational study Prospective cohort study, etc. Patient consent Register a clinical trial Meta-analysis 문헌 searching, review
6 논문의작성전고려사항 1 Authorship 결정 Authorship (ICMJE- 모든요소만족 ) 연구의개념과설계에참여 데이터수집과해석담당 논문초안작성에참여 논문최종본승인 Authorship 의원칙을미리정하여그원칙에따라 authorship 을결정저자들의역할배분 (Author contribution) 주저자 ( 제 1 저자, 교신저자 ), 공저자공저자순서 : 기여도에따른순서공동주저자 (Journal guideline 준수 ) 저자수의제한 (Journal guideline 준수 ) 되도록적게 Contributor Acknowledgement 단순재정취득, 자료수집, 일반적인감독, 연구재료제공, 조사자, 자문등 Gift author ( 선물저자 ), 유령저자 (ghost author), 교환저자 (swap author), 도용저자
7 논문의작성전고려사항 2 Target Journal 결정 Journal s aims & scope Journal of Chemotherapy vs. Annals of Surgical Oncology Cancer Research vs. Gynecologic Oncology Target readership ( 대상청중 ) Annals of Surgery vs. Annals of Surgical Oncology Threshold High threshold Significant advance NEJM, JAMA, LACNET Interest to generalized group Journal of Clinical Oncology Lancet Oncology Strong conclusion Low threshold Small Advance Interest to specialized group Gynecologic Oncology Journal of Gynecologic Oncology Weak conclusion Statistically less strong Missing control
8 논문의구성 (Original Article) Title Abstract Introduction Materials and Methods Results Discussion Conclusion Title Materials and Methods Results Conclusion Discussion Introduction Abstract
9 Title Reflecting the content of paper Specific & Descriptive Avoid unnecessary detail 연구형태를반영하는것이좋다 Prospective study, retrospective study, review Avoid abbreviations Use the common name Chemicals by formulas
10 Materials and Methods 연구를어떻게수행하였는지기술 부제목 (subheading) 을사용 Study population Statistical analysis Etc. 과거시제 이미잘알려진연구방법을사용한경우이전의논문을인용하고간략히기술 새로운연구방법을사용한경우에는상세히기술 Primary outcome measure 가무엇이며, 이를위해통계분석은어떻게하였는지기술 Ethic approval 과 patient consent 에대하여기술
11 Results 주요결과를표와그림으로만든다 : 논문의얼굴 표와그림을바탕으로결과를기술한다. 과거시제 표와그림은현재시제 결과를잘보여주어야한다. 핵심적인결과를보여주고 Supplementary materials 를이용한다. Subheadings 사용 순서를논리적으로잘배열 하지말아야할것 본문과표 / 그림은중복되지않도록한다. Brevity & Clarity Logical Materials and methods section 이나 Discussion section 에들어가야할내용을넣지않도록한다.
12 Conclusion 논문의결과를바탕으로한결론을간략하고명확히기술한다. 결과가뒷받침되는결론만적고, 과장해서는안된다. Preliminary outcome 인경우 future study 에대해언급한다.
13 Discussion 연구결과를어떻게해석하는지기술 주요결과는반드시 discussion 중요한결과에서중요성이낮은결과순으로 discussion 본연구결과와다른연구결과를비교 논문의장점을부각하고단점에대한방어 대개 4 개의 paragraph 정도의분량 주요결과를요약하고해석 이전연구들의고찰 본연구의차이점 본연구의장단점 피해야할것 장황한 book review Results section에없는본연구결과의제시
14 Reference Citation management program 사용 형식과개수는 Journal 투고규정에따라서 (30 개이내 ) Up-to-date reference 를인용 : 대개최근 10 여년이내 주요연구는반드시인용 (landmark study) Original study 를인용
15 Introduction 왜이연구를시행하게되었는지배경과연구목적을기술 3 paragraph / 1 page 질환에대한간단한기술과이제까지이루어진연구내용기술 아직연구가이루어지지않은것, 왜이연구를시행하게되었는지기술 본연구의목적을명확하게기술 짧고명확하게기술 관련된내용만기술 문헌 review 나 Book review 가되지않도록기술 이전연구결과들에대해한쪽으로치우치지않도록기술
16 Abstract Editor 와 reviewer 가논문을파악하기위해제일먼저보는것 논문의핵심내용이반드시들어가야한다. 제목과본문에사용된동일한용어를사용하고, 동일한내용이들어가야한다. 본문에없는내용이초록에기술되어서는안된다. Structure 준수 Background (Objective) : 30% Materials and Methods : 10% Results : 40% 구체적인수치와 p-value Conclusions : 20% 단어수준수 Reference, Abbreviation 은피할것 Keywords
17 임상연구논문작성시고려할사항 Journal style 준수 각 journal 마다제공하는 author guideline Journal-specific policy & instruction for authors Publication and research ethics guidelines 준수 ICMJE : International Committee of Medical Journal Editors CONSORT : Consolidated Standards of Reporting Trials COPE : Committee on publication Ethics WMA Declaration of Helsinki STROBE: STrengthening the Reporting of OBservational studies in Epidemiology
18 논문작성시반드시피해야할것 Fabrication ( 날조 ) Falsification ( 변조 ) Plagiarism ( 표절 ) : 자기만의언어로표현하고자료를사용 Verbatim 따옴표, 참고문헌인용 Paraphrasing ( 바꿔쓰기 ) 참고문헌인용 Summarizing ( 요약 ) 참고문헌인용 아이디어의표절 Reprint 사전허가를받아야한다 자기표절 다른언어로변역하여도마찬가지
19 논문초고작성후할일 Acknowledgement All kinds of support or contributors for writing and editing the manuscript Funding 사전동의를얻어야한다 Declare conflicts of interest of all authors 이해관계 : 논문의출판관관련된사람 ( 저자, 편집인, 전문가심사자, 출판인등 ) 또는기관이특정논문에재정적인이익이걸려있거나사적인특별한관련이있는경우 재적적인관계, 사적인관계, 연구의경쟁, 지적인관심사 Language editing Make sure all authors see the final version of the manuscript before submission 추천사항 동료들 (2 인이상 ) 로부터논문 review 를받아본다
20 Acknowledgements None. Thank you for your kind attention!!!
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