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2 후원 : 재단법인 당뇨병학연구재단

3 Invitation 24 th Spring Congress of Korean Diabetes Association 안녕하십니까? 2011년 신묘년 새해를 맞아 회원 여러분의 가정과 병원에 건강과 행운이 가득하시길 기원합니다. 대한당뇨병학회에서는 2011년 5월 12일부터 14일까지 광주 김대중컨벤션센터에서 제24차 대한당뇨병학회 춘계학술대회 및 총회를 개최하고자 합니다. 이번 학술대회에서는 당뇨병의 연구와 진료를 위해 애쓰시는 모든 회원들과 유관단체 및 의료관련 정책입안자 등이 모두 함께하여 당뇨병 및 관련 분야의 발전에 기여하고자, 2개의 Plenary lecture와 다양한 주제의 심포지엄, Young investigator award 초청강연, 포스터구연 발표, OLETF rat 연구세션, 간행위원회세션 및 보험법제 공청회로 구성하였습니다. 기조강연에는 연세의대 이현철 교수와 프랑스 Centre de Recherche des Cordeliers의 Fabienne Foufelle 교수가 맡으셨으며, 16세션으로 구성되어있는 심포지엄에서는 Islet biology & insulin secretion, Immunology & transplantation, Insulin action & obesity, Clinical diabetes & therapeutics, Epidemiology & genetics, Acute & chronic complication, Behavioral medicine & education에 관한 주제를 중심으로 준비하였고, 당뇨병과 암에 대한 Debate session과, 환경호르몬 과 대사질환에 대한 Challenging issue 세션을 마련하여 국내외 우수한 연구자들이 발표 할 예정입 니다. 또한 포스터구연 발표 시간에는 포스터 전시장에서 전시물을 보면서 발표자의 발표를 직접 듣 고 현장에서 토의하는 시간을 가질 예정입니다. 이번 춘계학술대회는 다양한 역사적 흔적과 문화자산을 가지고 있는 아름다운 도시 광주에서 개최 하게 되어 지방회원과 친밀한 교류를 할 수 있어 더 활기차고 알찬 학술대회가 될 것입니다. 또한 이 귀중한 자리가 여러 회원 분들께 유익한 교류와 친목을 도모할 수 있는 축제의 장이 되기를 기대합 니다. 회원 여러분의 적극적인 참여를 부탁 드립니다. 감사합니다. 대한당뇨병학회 회 장 김 진 우 이사장 박 성 우

4 Timetable 24 th Spring Congress of Korean Diabetes Association Room 1 Room 2 Room 3 Room 4 May 12 (Thu) 16:00~17:00 등록 17:00~18:00 Satellite symposium 1 Satellite symposium 2 Satellite symposium 3 18:00~ Welcome reception (Convention hall 4F, lobby) Islet biology & insulin secretion, immunology & transplantation May 13 (Fri) Insulin action & obesity Clinical diabetes & therapeutics 8:00~16:00 등록 7:30~8:30 Breakfast symposium 1 Breakfast symposium 2 9:00~11:00 S1 Insulin secretion and cell therapy for diabetes S2 Regulation of skeletal muscle physiology and metabolism 11:00~11:20 Coffee break 11:20~11:30 Opening address 11:30~12:10 Plenary lecture 1 12:10~12:40 총회 13:00~14:00 Luncheon lecture 1 Luncheon lecture 2 S3 Hepatosteatosis in type 2 diabetes Behavioral medicine & education S4 Type 2 diabetes, exercise and brain physiology 14:00~16:00 For advancement of KDA journals Poster presentation 1 (Convention hall 4F, lobby) 16:00~18:00 S5 An islet in distress - insulin secretion and pancreatic β cell failure S6 Mitochondria and metabolism S7 Update on the diagnosis and treatment of diabetic neuropathy 18:00~ Dinner (Holiday Inn 3F, Convention hall) May 14 (Sat) Acute & Epidemiology & genetics Insulin action & obesity chronic complication 8:00~16:00 등 록 7:30~8:30 Breakfast symposium 3 Breakfast symposium 4 9:00~11:00 S9 Diabetes, gut and environment S10 Challenging issue in obesity S11 New therapeutic strategies for diabetic complication S8 Nutrition and CVD in diabetes Behavioral medicine & education S12 Sexual dysfunction and diabetes 11:00~11:20 Coffee break 11:20~12:00 Plenary lecture 2 12:00~12:40 Young investigator award lecture 13:00~14:00 Luncheon lecture 3 Luncheon lecture 4 14:00~15:30 15:30~17:30 Special symposium: OLETF rat 연구세션 S13 Debate session: diabetes and cancer 보험법제 공청회 S14 Interaction between musculoskeletal system and energy metabolism 17:30~ Closing and award Poster presentation 2 (Convention hall 4F, lobby) S15 New drugs for glycemic control in type 2 diabetes S16 Exploration of SMBG recommendations and case based discussion of issues

5 Contents 24 th Spring Congress of Korean Diabetes Association Plenary lecture 1 May. 13(Fri), 11:30~12:10 / Room1,2,3 좌장: 김진우 2 Targeting the redox sensitive Nrf2/ARE defence pathway in diabetic vascular disease - protective role afforded by natural magnesium lithospermate B - Hyun Chul Lee (Yonsei University, Korea) Plenary lecture 2 May. 14(Sat), 11:20~12:00 / Room1,2,3 좌장: 박성우 6 The role of endoplasmic reticulum stress and lipogenesis in the development of hepatic steatosis Fabienne Foufelle (Centre de Recherche des Cordeliers, France) Islet transplantation & immunology S1 Insulin secretion and cell therapy for diabetes S1-1 Strategies to improve beta cell regeneration S1-2 Regulation of beta cell proliferation by serotonin S1-3 In vivo cell tracking with MRI May. 13(Fri), 9:00~11:00 / Room1 좌장: 이현철, 이명식 10 이문규 (성균관의대 내과) 김하일 (카이스트 의과학대학원) 문우경 (서울의대 영상의학과) Insulin action & obesity S2 Regulation of skeletal muscle physiology and metabolism May. 13(Fri), 9:00~11:00 / Room2 좌장: 강성구, 이관우 20 S2-1 Metabolic regulation in skeletal muscle 차봉수 (연세의대 내과) S2-2 E3 ligase TRIM72 negatively regulates myogenesis by IRS-1 ubiquitination 고영규 (고려대 생명과학부) S2-3 AMPK and AMPK-related protein kinases in skeletal muscle Ho-Jin Koh (Harvard Medical School, USA) S2-4 Antidiabetic and antiobesity effects of ampkinone (6f), a novel small molecule activator of AMP-activated protein kinase (AMPK) 박승범 (서울대 화학부) 제24차 대한당뇨병학회 춘계학술대회

6 Contents 24 th Spring Congress of Korean Diabetes Association Clinical diabetes & therapeutics S3 Hepatosteatosis in type 2 diabetes S3-1 Non-alcoholic fatty liver disease in metabolic syndrome S3-2 Elevated ER stress mediates hepatic steatosis via lipoprotein uptake S3-3 Hepatokines and hepatosteatosis Short talk 1 Therapeutic target of nonalcoholic fatty liver disease Short talk 2 The expression of LDL receptor related protein 1 in the liver and the brain: from diabetic dyslipidemia to Alzheimer s disease May. 13(Fri), 9:00~11:00 / Room3 좌장: 이태희, 이인규 30 조용균 (성균관의대 내과) 김재범 (서울대 생명과학부) 최경묵 (고려의대 내과) 김미경 (계명의대 내과) 문재훈 (연세의대 내과) Behavioral medicine & education (exercise) S4 Type 2 diabetes, exercise and brain physiology May. 13(Fri), 9:00~11:00 / Room4 좌장: 안유헌, 김용성 44 S4-1 Exercise and cerebral function S4-2 What s happening in the brain of exercising ZDF rats, animal model for diabetes? S4-3 Positive effects of exercise on diabetes mellitus, neurogenesis and depression in the hippocampal dentate gyrus Hideaki Soya (University of Tsukuba, Japan) 성제경 (서울대 수의대) 백성수 (상명대 체육학부) Islet biology & insulin signaling S5 An islet in distress - insulin secretion and pancreatic β cell failure May. 13(Fri), 16:00~18:00 / Room1 좌장: 김광원, 이형우 52 S5-1 Defects in glucose utilization and GLP-1 S5-2 Islet amyloid polypeptide in β cell S5-3 Protection of cytokine-induced pancreatic β-cell damage by targeting JAK3 and SIRT6 S5-4 Glucolipotoxicity in β cell 송대규 (계명의대 생리학교실) 이명식 (성균관의대 내과) 박병현 (전북의대 생화학교실) 윤건호 (가톨릭의대 내과) Insulin action & obesity S6 Mitochondria and metabolism May. 13(Fri), 16:00~18:00 / Room2 좌장: 이기업, 서교일 64 S6-1 NQO1, a versatile cytoprotective enzyme in response to age-related diseases S6-2 Mitochondrial biogenesis and diabetes, functional of confirmation mtdna transcription termination factor (MTERF) S6-3 Energy metabolism alterations in sepiapterine reductase deficiency S6-4 Role of mitochondrial OxPhos dysfunction in islet and adipose tissues for diabetes development 현동훈 (이화여대 생명과학과) 박찬배 (아주의대 의과학연구소) 한진 (인제의대 심혈관 대사질환 센터) 송민호 (충남의대 내과) 제24차 대한당뇨병학회 춘계학술대회

7 Contents 24 th Spring Congress of Korean Diabetes Association Acute & chronic complication S7 Update on the diagnosis and treatment of diabetic neuropathy S7-1 Recent expert opinions on the definition of diabetic neuropathy S7-2 The approach to the management of diabetic neuropathic pain S7-3 Cardiovascular autonomic dysfunction in patients with type 2 diabetes mellitus S7-4 Report on the prevalence and clinical characteristics of diabetic neuropathy in Korea May. 13(Fri), 16:00~18:00 / Room3 좌장: 정민영, 고경수 72 김종화 (세종병원 내과) 박태선 (전북의대 내과) 고승현 (가톨릭의대 내과) 원종철 (인제의대 내과) Behavioral medicine & education (nutrition) S8 Nutrition and CVD in diabetes S8-1 Fat and CVD S8-2 Carbohydrate and CVD S8-3 Dietary patterns and CVD risk S8-4 Dietary guideline and adherence for CVD May. 13(Fri), 16:00~18:00 / Room4 좌장: 임성희, 김인주 84 조동혁 (전남의대 내과) 노민영 (서울성모병원 영양과) 송윤주 (가톨릭대 식품영양학과) 임정현 (서울대병원 급식영양과) Epidemiology & genetics S9 Diabetes, gut and environment S9-1 The metabolic relevance of gastrointestinal physiology S9-2 Gut flora and host metabolism: lesson from a genetic animal model study S9-3 The enteroinsular axis in the pathogenesis of prediabetes and diabetes S9-4 Metabolic roles of endocannabinoid system in alcoholic fatty liver May. 14(Sat) 9:00~11:00 / Room1 좌장: 김영건, 최문기 106 김정국 (경북의대 내과) 이원재 (서울대 생명과학부) 조영민 (서울의대 내과) 정원일 (카이스트 의과대학원) Insulin action & obesity S10 Challenging issue in obesity: environmental hormone and metabolism S10-1 Persistent organic pollutants and diabetes: epidemiological perspective S10-2 Cause-effect association of elevated serum dioxin-like compounds and mitochondrial dysfunction with metabolic syndrome S10-3 Environmental pollutants: the dark side of the food May. 14(Sat) 9:00~11:00 / Room2 좌장: 이홍규, 손호영 116 이덕희 (경북의대 예방의학교실) 김영미 (경희의대 생리학교실) Jérôme Ruzzin (University of Bergen, Norway) 제24차 대한당뇨병학회 춘계학술대회

8 Contents 24 th Spring Congress of Korean Diabetes Association Acute & chronic complication S11 New therapeutic strategies for diabetic complication May. 14(Sat) 9:00~11:00 / Room3 좌장: 김용기, 유형준 124 S11-1 Updates on diabetic retinopathy: anti-vegf therapy and sutureless microincision vitrectomy surgery (MIVS) S11-2 Emerging concepts of pathogenesis and new treatment for diabetic nephropathy S11-3 Autologous stem cell therapy for diabetic limb ischemia S11-4 Stem cell therapy for ischemic heart disease 윤영희 (울산의대 안과) 김수완 (전남의대 내과) 조진현 (경희의대 외과) 강현재 (서울의대 내과) Behavioral medicine & education (education) S12 Sexual dysfunction and diabetes S12-1 Diabetic autonomic neuropathy and erectile dysfunction S12-2 Psychiatric approach to the diabetic patients with sexual dysfunctions S12-3 Educational approach for sexual dysfunction of diabetes S12-4 Social work approaches for diabetic patients with sexual problem May. 14(Sat) 9:00~11:00 / Room4 좌장: 신순현, 우정택 140 조동혁 (전남의대 내과) 송지영 (경희의대 신경정신과) 홍명희 (서울백병원 간호과) 이지현 (강남세브란스병원 사회사업팀) Epidemiology & genetics S13 Debate session: diabetes and cancer S13-1 Increased risk of cancer with anti-daibetes drugs? : pros S13-2 Increased risk of cancer with anti-daibetes drugs? : cons May. 14(Sat) 15:30~16:30 / Room1 좌장: 김덕규, 윤건호 152 김난희 (고려의대 내과) 김동준 (인제의대 내과) Insulin action & obesity S14 Interaction between musculoskeletal system and energy metabolism May. 14(Sat) 15:30~17:30 / Room2 좌장: 김성연, 배학연 160 S14-1 Osteocalcin and diabetes S14-2 Exercise and myokines S14-3 Vitamin K2 supplementation improves insulin sensitivity via osteocalcin metabolism: a placebo-controlled trial S14-4 Role of BMP4 in obesity and metabolic syndrome S14-5 Vitamin D, metabolic syndrome and diabetes 정호연 (경희의대 내과) 민경완 (을지의대 내과) 신찬수 (서울의대 내과) 권혁상 (가톨릭의대 내과) 김혜진 (아주의대 내과) 제24차 대한당뇨병학회 춘계학술대회

9 Contents 24 th Spring Congress of Korean Diabetes Association Clinical diabetes & therapeutics S15 New drugs for glycemic control in type 2 diabetes May. 14(Sat) 15:30~17:30 / Room3 좌장: 민헌기, 조정구 180 S15-1 New therapeutic agents; SGLT2 inhibitors S beta-HSD type 1 inhibitor; under investigation for obese type 2 diabetic patients S15-3 Bromocriptine; new indication for glycemic control in type 2 diabetes S15-4 Colesevelam; dual efficacy in glycemic control and LDL-C reduction 오지영 (이화의대 내과) 이정민 (가톨릭의대 내과) 박병현 (원광의대 내과) 김대중 (아주의대 내과) Behavioral medicine & education (self care) S16 Exploration of SMBG recommendations and case based discussion of issues May. 14(Sat) 15:30~17:30 / Room4 좌장: 송복례, 유주화 194 S16-1 Postprandial glucose and glycemic variability S16-2 Use of SMBG S16-3 Real-time continuous glucose monitoring 이정화 (강동경희대병원 당뇨병교육실) 심강희 (삼성서울병원 간호과) 구민정 (서울대병원 소아청소년당뇨병교실) Special symposium 1 For advancement of KDA journals 1. Why should we add the journal to the international databases? 2. Development strategy for Diabetes and Metabolism Journal 3. Development strategy for The Journal of Korean Diabetes May. 13(Fri), 14:00~16:00 / Room1 좌장: 박성우, 손현식 212 허선 (한림의대 기생충학과) 이원영 (성균관의대 내과) 안철우 (연세의대 내과) Special symposium 2 OLETF rat and research May. 14(Sat) 14:00~15:30 / Room1 좌장: 김두만 OLETF rats: as a model for the metabolic syndrome and diabetic nephropathy in humans Kazuya Kawano (Otsuka Pharmaceutical Tokushima Research Institute) 2. Use of OLETF rat in studying the pathogenesis of diabetes and its complications 3. Study of hepatic lipid metabolism in OLETF rats 고은희 (울산의대 내과) 문재훈 (연세의대 내과) Special symposium 3 당뇨병 관련 보험 현안 공청회 May. 14(Sat) 16:30~17:30 / Room1 좌장: 박태선 228 당뇨병관리 필수소모품 보험급여화 당뇨병약제의 새로운 보험급여기준 박석오 (광명성애병원 내과) 방혜자 (복지부 보험약제과) 제24차 대한당뇨병학회 춘계학술대회

10 Contents 24 th Spring Congress of Korean Diabetes Association Satellite symposium 1 5월12일(17:00~18:00), Room1 / 좌장: 김선우 232 Recent controversies in the treatment of HTN - focused on ARBs 김신곤 (고려의대 내과) Satellite symposium 2 5월12일(17:00~18:00), Room2 / 좌장: 이문규 234 Basal insulin and T2DM management: enhancing care for patients 오승준 (경희의대 내과) Satellite symposium 3 The GLP-1 receptor agonist exenatide and its effects in type 2 diabetes 5월12일(17:00~18:00), Room3 / 좌장: 이현철 Michael E. Traumann (Lilly Research Laboratories) 236 Breakfast symposium 1 5월13일(7:30~8:30), Room1 / 좌장: 김태화 238 Incretin based therapies in the management of type 2 diabetes 박정현 (인제의대 내과) Breakfast symposium 2 5월13일 (7:30~8:30), Room3 / 좌장: 최동섭 240 Exploring new pathways in the management of diabetes through DPP-4 inhibitor 조영민 (서울의대 내과) Breakfast symposium Where are we in diabetic peripheral neuropathy? 5월14일(7:30~8:30), Room1 / 좌장: 조용욱 김종화 (세종병원 내과) Breakfast symposium Residual risk reduction in the treatment of diabetic dyslipidemia 5월14일(7:30~8:30), Room3 / 좌장: 이병두 김두만 (한림의대 내과) Luncheon symposium 1 5월13일(13:00~14:00), Room1 / 좌장: 최영길 246 Importance of diabetic peripheral neuropathic pain treatment for the diabetic patients 박태선 (전북의대 내과) Luncheon symposium 2 5월13일(13:00~14:00), Room2 / 좌장: 백세현 250 DPP-4 inhibitors: comparative review 윤건호 (가톨릭의대 내과) Luncheon symposium 3 5월14일(13:00~14:00), Room1 / 좌장: 허갑범 252 Tailored statin therapy in diabetic and non-diabetic patients 장상아 (가톨릭의대 내과) Luncheon symposium 4 5월14일(13:00~14:00), Room2 / 좌장: 차봉연 254 The PREDICTIVE study Korea result 고경수 (인제의대 내과) 제24차 대한당뇨병학회 춘계학술대회

11 POSTER * 표시는 포스터 구연으로 선정된 초록입니다. Islet biology & insulin secretion, immunology & transplantation 259 P1* 간 내 췌도 이식에서 췌도 자기 공명 영상으로부터 도출한 functioning islet mass의 정량적 표지자 진상만*, 오승훈, 서성환, 허규연, 김재현, 정재훈, 민용기, 이명식, 이문규, 김광원 성균관대학교 의과대학 삼성서울병원 내분비-대사내과 P2* Gene transfer of glucagon-like peptide-1 to mouse islets using nonviral carrier improves transplantation outcome Hee Young Chae 1 *, Jun Goo Kang 1, Chul Sik Kim 1, Seong Jin Lee 1, Moon Gi Choi 1, Hyung Joon Yoo 1, Minhyung Lee 2, Sung-Hee Ihm 1 Internal Medicine, College of Medicine, Hallym University, Chuncheon 1, Bioengineering, Hanyang University, Seoul 2, Korea P3* Betacellulin increases IRS-2 expression through ErbB-1 and ErbB-2 receptors, contributing to beta cell proliferation 오윤신*, 이연정, 전희숙 Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science P4* Subclinical beta cell specific mitochondrial dysfunction results accelerated islet failure in mice with high caloric diet 김용경 1 *, 김성중 1, 유민정 1, 이민희 1, 이성은 1, 최민정 1, 정효균 1, 김군순 1, 구본정 1, 권기량 2, 이철호 3, 송민호 1 Research Center for Endocrine & Metabolic Disease, Chungnam National University School of Medicine, Deajeon 1, Department of Biochemistry, Chungnam National University School of Medicine, Deajeon 2, Animal Model Center, Korea Research Institute of Bioscience & Biotechnology (KRIBB), Deajeon 3 P5* Glucose-induced secretion of glucagon-like peptide-1 involves the SGLTs expression in L-cells Dong-Mee Lim*, Ju-Young Kim, Ji-Hyun Kim, Youn-Zoo Cho, Hye-Jin Yoon, Keun-Young Park, Byung-Joon Kim Division of Endocrinology, Department of Internal Medicine, Konyang University School of Medicine, Daejeon P6* Mechanism contributing antioxidant effects of thiazolidinediones in pancreatic β cells Min Kim*, Sung Soo Chung, Ji Seon Lee, Byung Yong Ahn, Hye Seung Jung, Kyong Soo Park Department of Internal Medicine, Seoul National University College of Medicine P7* The effect of hypoglycemia on apoptosis of INS-1 cells and rat islets cultured in glucotoxic condition compared to normoglycemia Mi Kyung Kim 1 *, Hye Suk Jung 2, Chang Sin Yoon 2, Tae Kyun Kim 3, Min Jung Kwon 3, Sun Hee Lee 3, Byoung Doo Rhee 3, Jeong Hyun Park 3 Department of Internal Medicine, Maryknoll Medical Center, Busan 1, Molecular Therapy Lab, Paik Institute for Clinical Research, Inje University, Busan 2, Department of Internal Medicine, College of Medicine, Inje University, Busan 3 P8* Autophagy-deficiency in β-cells leads to compromised unfolded protein response and progression from obesity to diabetes Wenying Quan 1 *, Kyu Yeon Hur 1, Yu-Mi Lim 1, Seung Hoon Oh 1, Jun-Chul Lee 1, Kook Hwan Kim 1, Hong Lim Kim 2, Moon-Kyu Lee 1, Kwang-Won Kim 1, Jin Kim 2, Masaaki Komatsu 3, Myung-Shik Lee 1 Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine 1, Department of Anatomy and Cell Death Disease Research Center, College of Medicine, The Catholic University of Korea 2, Laboratory of Frontier Science, Tokyo Metropolitan Institute of Medical Science 3 P9 P10 Exendin-4에 의한 SREBP1 조절이 INS-1 베타세포에서 고농도 포도당/지방산에 의해 유도되는 ER stress에 미치는 효과 이연정*, 오윤신, 전희숙 가천의과학대학교 이길여암당뇨연구원 2-aminobicyclo[2.2.1]heptan-2-carboxylic acid (BCH) protected β-cell in db/db mice 한승진 1 *, 최성이 1, 곽지영 1, 박진주 1, 안소연 1, 이민석 1, 최용준 1, 김혜진 1, 김대중 1, 이관우 1, 강 엽 2 아주대학교 내분비대사 내과 1, 아주대학교 내분비 연구소 2

12 P11 The phosphorylation and acetylation of FOXO of INS cell under sustained high glucose and intermittent high glucose Mikyung Kim 1 *, Hyesuk Chung 2, Changsin Yoon 2, Taekyun Kim 3, Minjeong Kwon 3, Soonhee Lee 3, Byoungdoo Rhee 3, Jeonghyun Park 3 Department of Internal Medicine, Maryknoll General Hospital, Busan 1, Molecular Therapy Lab, Paik Institute for Clinical Research, Inje University, Busan 2, Department of Internal Medicine, College of Medicine, Inje University, Busan 3 Insulin action & obesity 264 P12* Predominant M1 macrophage infiltration and insulin resistance in mice model of adipose mitochondrial dysfunction Min Jeong Ryu 1 *, Soung Jung Kim 1, Yong Kyoung Kim 1, Min Hee Lee 1, Seong Eun Lee 1, Min Jeong Choi 1, Kyoung-Hye Jung 1, Hyun Jin Kim 1, Young Suk Jo 1, Gi Ryang Kweon 2, Minho Shong 1 Research Center for Endocrine and Metabolic Diseases, Department of Internal Medicine 1, Department of Biochemistry 2 P13* Deficiency of pyruvate dehydrogenase kinase 2 (PDK2) reduces fasting blood glucose levels and fat accumulation in the liver of mice fed a high fat diet Ji Yun Jeong 1 *, Yunghoon Go 1, Nam Ho Jeoung 2, Eon-Ju Jeon 1, Hyun-Ae Seo 1, Jung-Guk Kim 1, Yeon Kyung Choi 1, Rovert A. Harris 3, In-Kyu Lee 1 Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea 1, Department of Fundamental Medical and Pharmaceutical Sciences, Catholic University, Daegu, Korea 2, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, U.S.A. 3 P14* Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in obese diabetic mice Young-Sun Lee 1 *, Mi-Sung Park 1, Jin-Seung Choung 1, Seung Yeon Ha 2, Hee-Sook Jun 1 Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science 1, Department of Pathology, Gachon University Gil Hospital 2 P15* Mitochondrial dysfunction and activation of inducible nitric oxide synthase are responsible for palmitate-induced endoplasmic reticulum stress and decreased adiponectin synthesis in 3T3-L1 adipocytes Jaechan Leem*, Eun Hee Koh, Mi-Seon Shin, Eun Hee Kim, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Ki-Up Lee Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea P16* Adipose BNIP3 expression in obese animal model and its regulation by rosiglitazone Anna Jo 1 *, Shin Ae Kang 2, Min Kim 1, Sung Soo Chung 1, Kyong Soo Park 1 서울대병원 1, 강남세브란스병원 2 P17* Cytochrome P450 4A regulates endoplasmic reticulum stress-induced insulin resistance and apoptosis in type 2 diabetic liver 박창균*, 이동규, 홍연희, 김건화 Korea Basic Science Institute P18* The effects of Resveratrol on insulin action under various in vitro and in vivo conditions Jian Guan 1 *, Wonyoung Kang 2, Doekbae Park 1, Sang Ah Lee 3, Gwanpyo Koh 3, Chang Hoon Han 2, Young-Jae Lee 2, Dae Ho Lee 1 Department of Medicine, School of Medicine, Institute of Medical Science, Jeju National University 1, Department of Toxicology & Biochemistry, College of Veterinary Medicine, Jeju National University 2, Department of Internal Medicine, Jeju National University Hospital 3 P19 Visceral fat measured by the electrical impedance analysis method is a good predictor of insulin resistance 김민경 1 *, 이인석 2, 장혜원 1, 정경혜 1, 김군순 1, 김현진 1, 이태영 3, 김영군 1, 구본정 1 충남대학교병원 내과 1, 대전 성모병원 내과 2, 충남대학교 의과대학 예방의학과 3

13 P20 P21 P22 P23 P24 P25 P26 P27 P28 P29 Android fat depot is more closely associated with metabolic syndrome than abdominal visceral fat in elderly people: the Korean longitudinal study on health and aging Seon Mee Kang 1 *, Soo Lim 1, Sung Hee Choi 1, Ji Won Yoon 2, Hwa Young Ahn 1, Min Joo Kim 1, Yenna Lee 1, Eun Shil Hong 3, Eunky Kim 3, Yean Kim 3, Hak Chul Jang 1 Department of Internal Medicine, Seoul National University Bundang Hospital 1, Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital 2, Department of Internal Medicine, Seoul National University Hospital 3 Cathepsin K, L expression in adipocytes is upregulated by palmitate via TNFα and IL-6 Jeong Seon Yoo 1 *, YoungMi Lee 1, Eun Hae Lee 1, ShinYoung Lee 1, Ji Woon Kim 1, Jong Suk Park 1, Chul Woo Ahn 1, Kyung Rae Kim 1, Jae-woo Kim 2, Shin Ae Kang 1 Endocrinology and Metabolism, Department of Internal Medicine, Gangnam Severance Hospital of Yonsei University, College of Medicine, Seoul, Korea 1, Department of Biochemistry and Molecular Biology, Center for Chronic Metabolic Disease Research, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea 2 Maternal obesity and weight gain during pregnancy as a risk factor for macrosomia independent of gestational diabetes mellitus Kyung Ju Lee 1 *, Kyung Sun Park 2, Soo Kyung Kim 2, Yoo Lee Kim 3, Yong Wook Cho 2, Seok Won Park 2 Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University 1, Department of Internal Medicine, CHA Bundang Medical Center, CHA University 2, Department of Internal Medicine, CHA Gangnam Medical Center, CHA University 3 Akt인산화 억제를 통한 스타틴의 인슐린저항성 유발효과 하원철 1 *, 오수진 1, 전부석 1, 이지인 1, 김지현 2, 이정민 2, 장상아 2, 이혜민 1, 손현식 1 가톨릭대학교 의정부 성모병원 1, 가톨릭대학교 성바오로병원 2 DMSO reduces hepatocellular lipid accumulation by ATF4-mediated autophagy 송영미*, 송순옥, 차봉수, 이은직, 이현철, 이병완 Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine The effect of clusterin on hepatic lipogenesis Eon Ju Jeon 1 *, Hye Young Seo 1, Han Jong Kim 1, Joon Young Kim 1, Young Keun Choi 1, Ji Hyun Kim 1, Ji Yun Jeong 1, Hyun Ae Seo 1, Yeun Kyung Choi 1, Jung Guk Kim 1, Keun Gyu Park 2, In Kyu Lee 1 Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea 1, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea 2 Fibroblast growth factor 21의 인간 근관세포에서 palmitate 유발성 인슐린 저항성 억제 효과의 기전: NF-kB와 스트레스 키나아제의 억제 이민석 1 *, 최용준 1, 안소연 1, 김은경 1, 하은숙 1, 최성이 1, 김태호 2, 한승진 1, 김혜진 1, 김대중 1, 강 엽 3, 이관우 1 아주대학교 의과대학 내분비대사내과학교실 1, 관동대학교 의과대학 내분비대사내과학교실 2, 아주대학교 의과대학 의과학 연구소 3 알코올 투여가 OLETF 쥐의 간과 췌장에서 세포질 세망 스트레스에 미치는 영향 이성수*, 정희경, 손장원, 김성래, 유순집 가톨릭대학교 내분비 내과학교실 Retinol-binding protein 4와 심혈관계 질환과의 연관성 김정민 1 *, 박철영 2, 고경수 3, 이병두 3, 원종철 3 인제대학교 상계백병원 내과 1, 성균관대학교 강북삼성병원 내과 2, 인제대학교 상계백병원 내과, 인제대학교 심혈관대사질 환 연구센터 3 Time-dependent changes in lipid metabolism and endoplasmic reticulum stress in methionine choline deficiency-induced fatty liver disease Jaechan Leem 1 *, Eun Hee Koh 1, Hansol Park 2, Byeong Hwan Jeon 2, Woo Je Lee 1, Min-Seon Kim 1, Joong-Yeol Park 1, Ki-Up Lee 1 Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea 1, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, Republic of Korea 2

14 P30 P31 P32 P33 Exendin-4 relieves palmitate-induced ER stress and apoptosis in HepG2 cells by enhancing SIRT1 expression JinMi Lee 1 *, Seok-Woo Hong 1, Ji-Hun Choi 2, Se-Eun Park 2, Eun-Jung Rhee 2, Cheol-Young Park 2, Ki-Won Oh 2, Sung-Woo Park 2, Sun-Woo Kim 2, Won-Young Lee 2 Institute of Medical Research, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea 1, Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea 2 Protective effect of Exendin-4 against lipotoxicity-induced β cell dysfunction and apoptosis by decreasing SREBP1c expression 홍석우 2 *, 이진미 2, 최지훈 1, 박세은 1, 이은정 1, 박철영 1, 오기원 1, 박성우 1, 김선우 1, 이원영 1 강북삼성병원 의학연구소 1, 강북삼성병원 내분비내과 2 Different effects of nicotinamide and nicotinic acid on NAD-sirtuin pathway Soo Jin Yang 1 *, Jung Mook Choi 1, Lisa Kim 1, Won Jun Kim 2, Se Eun Park 2, Eun Jung Rhee 2, Won Young Lee 2, Ki Won Oh 2, Sung Woo Park 2, Sun Woo Kim 2, Cheol-Young Park 2 Diabetes Research Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine 1, Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine 2 Treatment with bitter melon (momordica charantia) prevents hyperglycemia and inflammation in high fat fed rats Jung Mook Choi 1 *, Soo Jin Yang 1, Lisa Kim 1, Heekwan Won 2, Won Jun Kim 2, Se Eun Park 2, Eun Jung Rhee 2, Won Young Lee 2, Ki Won Oh 2, Sung Woo Park 2, Sun Woo Kim 2, Cheol-Young Park 2 Diabetes Research Institute, Kangbuk Samsung Hospital, Seoul, Korea 1, Department of Internal Medicine, Division of Endocrinology and Metabolism, School of Medicine, Sungkyunkwan University, Kangbuk Samsung Hospital, Seoul, Korea 2 Clinical diabetes & therapeutics 275 P34* The ratio of glycated albumin to glycated hemoglobin (GA/A1c) is correlated with insulin secretion, not insulin resistance measured by standardized liquid diet Da Ham Kim*, Kyoung Min Kim, Kwang Joon Kim, Bong Soo Cha, Hyun Chul Lee, Byung-Wan Lee Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea P35* Serum selenoprotein P levels in patients with type 2 diabetes and prediabetes: implications for insulin resistance, inflammation, and atherosclerosis 양세정*, 홍호철, 최혜윤, 김윤정, 조명진, 은채령, 김주형, 류혜진, 김희영, 서지아, 김신곤, 김난희, 백세현, 최동섭, 최경묵 고려대학교 의과대학 내과학교실 P36* 제2형 당뇨병 환자의 혈청 fibroblast growth factor 21 정도와 공복 혈당, γ-glutamyltransferase, 당뇨병성 망막증과의 관련성 안소연 1 *, 박진주 1, 이민석 1, 최용준 1, 곽지영 1, 한승진 1, 김혜진 1, 김대중 1, 강 엽 2, 이관우 1 아주대학교 의과대학 내분비대사내과학교실 1, 아주대학교 의과대학 의과학 연구소 2 P37* Serum FGF21 concentrations are associated wtih dyslipidemia, insulin resistance, and metabolic syndrome 이예나*, 김민주, 홍은실, 김은기, 강선미, 윤지완, 정혜승, 박경수, 장학철, 최성희 서울대학교 의과대학 내과학교실 P38* Fibroblast growth factor 21 as a marker of coronary artery diseases in Korean type 2 diabetic patients Hee Ja Ko*, Ki Won Kim, Bo Yeon Kim, Chan Hee Jung, Sung Wan Jeon, Ji Oh Mok, Hyeong Kyu Park, Chul Hee Kim, Sang Jin Kim, Dong Won Byun, Kyo Il Suh, Myung Hi Yoo, Sung Gu Kang, Yeo Joo Kim Department of Internal Medicine University of SoonChunHyang College of Medicine, Cheonan, Korea

15 P39* Effects of a three-month combined exercise program on fibroblast growth factor 21 and fetuin-a levels and arterial stiffness in obese women 홍호철*, 양세정, 최혜윤, 류혜진, 은채령, 김윤정, 조명진, 김주형, 김희영, 서지아, 김난희, 김신곤, 백세현, 최동섭, 최경묵 고려대학교 부속병원 내분비-대사내과 P40* Effect of early intensive insulin therapy on body composition and insulin sensitivity in newly diagnosed type 2 diabetes 손장원 1 *, 정희경 1, 이성수 1, 김성래 1, 차봉연 2, 손호영 2, 유순집 1 부천성모병원 1, 서울성모병원 2 P41* 당뇨병이 동반된 임산부를 위한 IT 기반 당뇨 관리 시스템의 효과 분석 Hun Sung Kim 1 *, Yoon Hee Choi 1, Sung Min Han 2, Jeong Ah Oh 3, Jae Hyoung Cho 1, Jin Hee Lee 3, Mi Ja Kang 3, Kun Ho Yoon 1 가톨릭대학교 서울성모병원 1, 미즈메디병원 2, 가톨릭대학교 유헬스케어사업단 3 P42* 당뇨병환자에서의 IMT와 지방간의 연관성 홍상모*, 이건화, 이창범, 박용수, 김동선, 최웅환, 김태화, 안유헌 한양대학교 의과대학 내분비 대사내과 P43* 한국인 제2형 당뇨병의 인슐린 저항성에 따른 임상적 생화학적 특성 이은영 1 *, 최영주 2, 김철식 3, 이은직 1, 허갑범 2 연세대학교 의과대학 내분비내과 1, 허내과/21세기 당뇨병 혈관연구소 2, 한림대학교 의과대학 내분비내과 3 P44* Circulating osteocalcin level is associated with improved glucose tolerance, insulin secretion and sensitivity independent of the plasma adiponectin level You-Cheol Hwang*, In-Kyung Jeong, Sang Ouk Chin, Moon Chan Choi, Sang Youl Rhee, Suk Chon, Seungjoon Oh, Kyu Jeung Ahn, Jeong-taek Woo, Sung Woon Kim, Jin-Woo Kim, Young Seol Kim, Ho Yeon Chung Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea P45* Pentoxifylline attenuates oxidative stress and endoplasmic reticulum stress in rat with methionin- and cholin-deficient-diet induced experimental hepatosteatitis Min Kyung Chae 1 *, Kyeong Hye Park 1, Myung Won Lee 2, Bong Soo Cha 1, Hyun Chul Lee 1, Byung-Wan Lee 1 연세대학교 의과대학 1, 광명성애병원 2 P46* Exendin-4 increased bone mineral density through osteocyte in type 2 diabetic rat Ju-Young Kim 1 *, Ji-Hyun Kim 1, Seong-Kyu Lee 2, Kyung-Jin Jo 2, Dong-Mee Lim 1, Keun-Young Park 1, Byung-Joon Kim 1 Division of Endocrinology, Department of Internal Medicine, Konyang University School of Medicine, Daejeon, Korea 1, Department of Biochemistry and Molecular Biology, Eulji University School of Medicine, Daejeon, Korea 2 P47* 당지질독성 환경 내 INS-1 세포에서 다양한 농도의 글리벤클라마이드가 사멸과 세포질세망 스트레스에 미치는 영향 권민정 2 *, 이은주 2, 정혜숙 1, 윤창신 1, 김태균 2, 이순희 2, 김미경 3, 박정현 2 백인제임상의학연구소 분자치료실험실 1, 인제대학교 의과대학 내분비대사내과 2, 메리놀병원 내분비대사내과 3 P48* Anti-diabetic effects of a novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor, KR 박지선*, 이상달, 김희연, 정원훈, 김타잔, 배규환, 강남숙, 배명애, 안성훈, 강승규, 안진희, 김기영 한국화학연구원 P49* Changes of catecholamine secretion from the perfused adrenal medulla of the alloxan-induced diabetic rat 임동윤 2 *, 배학연 1 Department of Internal Medicine (Diabetology) 1 and Department of Pharmacologyx 2, College of Medicine, Chosun University, Gwangju, Korea P50* Beraprost sodium attenuates 2-deoxy-D-ribose-induced production of pro-atherogenic factors in human umbilical vein endothelial cells Kwang Sik Suh 1 *, Yun Jung Lee 2, Sang Ouk Chin 3, Moon Chan Choi 3, Suk Chon 3, Seungjoon Oh 3, Jeong-taek Woo 3, Sung Woon Kim 3, Jin Woo Kim 3, Young Seol Kim 3 Research Institute of Endocrinology, Kyung Hee University Medical Center 1, Department of Endocrinology and Metabolism, Everone Clinic 2, Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine 3

16 P51* Effect of glucokinase activators on proliferation and apoptosis in pancreatic INS-1 beta cells 오윤신*, 이연정, 전희숙 Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science P52* Insulin producing cell differentiation potential of human adipose tissue-derived stem cells during expanded culture in vitro Lan Dao Thi Mai*, Ok-Kuyng Hwang, Eun-Young Park, Hee-Sook Jun Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea P53 P54 P55 P56 P57 P58 P59 P60 P61 P62 Peroxisome proliferator receptor delta agonist attenuates hepatic steatosis by anti-inflammatory mechanism Mi Young Lee 1 *, Ran Choi 1, Eun Ju Cho 1, Bo Hwan Kim 2, Jarinyaporn Naowaboot 1, Chan Sik Won 1, Young Chul Yang 3, Jang Yel Shin 1, Young Goo Shin 1, Choon Hee Chung 1 Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea 1, Department of Nursing, Gachon University of Medicine and Science, Incheon, Korea 2, Department of Anatomy, Yonsei University Wonju College of Medicine, Wonju, Korea 3 제2형 당뇨병 환자의 주요 심혈관 사건 예측에 있어서 아포지단백 B와 아포지단백 B/아포지단백 A-1의 비의 유용성 김태호 1 *, 김윤지 1, 김세화 1, 온겨레 1, 강민정 1, 이현정 2, 정인빈 2, 하지민 2, 김형진 1 관동대학교 의과대학 명지병원 내분비내과 1, 관동대학교 의과대학 명지병원 영양팀 2 제2형 당뇨병 환자의 주요 심혈관 사건 예측에 있어서 피브리노겐과 고밀도 지단백 콜레스테롤의 유용성 김윤지 1 *, 김태호 1, 김세화 1, 온겨레 1, 강민정 1, 이현정 2, 정인빈 2, 하지민 2, 김형진 1 관동대학교 명지병원 내분비내과 1, 관동대학교 명지병원 영양팀 2 U-Healthcare 연구 이후 당뇨병 환자들의 혈당 조절 상태 김민주 1 *, 이예나 1, 홍은실 2, 임정아 2, 안화영 1, 강선미 1, 최성희 1, 임 수 1, 장학철 1 분당서울대학교병원 내분비내과 1, 서울대학교병원 내분비내과 2 Analysis of factors associated with pancreatic β-cell function in Korean patients with type 2 diabetes 김보연*, 김철희, 목지오, 정찬희, 강성구 순천향대학교병원 Impact of metaboic syndrome on the relationship between apob level and cardiovascular risk factors in type 2 diabetes patients 고관표 1 *, 이상아 1, 이대호 1, 임동미 2, 이강우 2, 김병준 2, 박근용 2, 진현정 3 제주대학교병원 1, 건양대학교병원 2, 한국병원 3 Retinol-binding protein 4 and arterial stiffness in patients with type 2 diabetes JinYoung Yoo*, JiYeon Lee, YounHee Park, JiYeon Kim, DongWon Byun, KyoIl Suh, MyungHee Yu, HyeongKyu Park 순천향대학교 서울병원 내분비내과 Human resistin is not associated with mortality in severe sepsis in endotoxemic mice Ji-Yeon Lee 1 *, Jin-Young Yoo 1, Youn-Hee Park 1, Dong-won Byun 1, Kyo-Il Suh 1, Myung-Hee Yu 1, Rexford Ahima 2, Michell Lazar 2, Hyeong-Kyu Park 1 순천향대학교 서울병원 내분비내과 1, Department of Medicine and IDOM, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA 2 Pregnancy outcomes according to existence of fasting hyperglycemia Kyung Sun Park 1 *, Kyung Ju Lee 2, Hyun Ju Oh 1, Soo Kyung Kim 1, Yoo Lee Kim 3, Yong Wook Cho 1, Seok Won Park 1 Department of Internal Medicine, CHA Bundang Medical Center, CHA University 1, Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University 2, Department of Internal Medicine, CHA Gangnam Medical Center, CHA University 3 A case of fulminant type 1 diabetes mellitus (FT1DM) combined with acute pancreatitis Seok Hong Lee*, Jea woong Kim, Moon Ki Hong, Seonghyup Hyun, Mi Yi Kim, Jihyun Ahn, Jaetaek Kim Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, Chung-Ang University

17 P63 P64 P65 P66 P67 P68 P69 P70 P71 P72 P73 P74 한국의 젊은 제2형 당뇨병 환자에서 비만 및 인슐린 저항성과 장기적인 혈당조절과의 관계 장윤미*, 김동림, 송기호, 김숙경 건국대학교 의학전문대학원 내과학교실 Ketosis-prone type 2 diabetes is not uncommon in Korean subjects with new-onset diabetes presenting with diabetic ketoacidosis Hannah Seok*, Yumie Rhee, Bong Soo Cha, Hyun Chul Lee, Byung-Wan Lee Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine 2형 당뇨병에서 인슐린자가항체와 인슐린수용체자가항체 양성인 자가면역 저혈당 1 예 서현애*, 최연경, 김종호, 하인균, 정지윤, 전언주, 김정국, 이인규 경북대학교 의학전문대학원 내과학교실 제2형 당뇨병환자에서 ω-3 지방산 투여 후 저밀도지단백 분획, 아디포넥틴 및 아포지단백B의 변화 이은주 2 *, 전혜정 2, 고정해 2, 정혜숙 1, 윤창신 1, 김태균 2, 권민정 2, 이순희 2, 석지혜 3, 김미경 3, 김덕규 4, 박정현 2 백인제 임상의학연구소 분자치료 실험실 1, 인제대학교 의과대학 내분비대사내과 2, 메리놀병원 내분비대사내과 3, 동아대 학교 의료원 내분비대사내과 4 노인 제 2형 당뇨 환자에서 ubiquitous healthcare service가 건강 관련 삶의 질에 미치는 영향 홍은실*, 김민주, 이예나, 김예안, 김은기, 안화영, 윤지완, 강선미, 최성희, 임 수, 장학철 서울대학교 의과대학 내과학교실 Glycemic effects of once a day ultra-short-acting insulin analogue addition on basal insulin analogue in poorly controlled Korean type 2 diabetic subjects Eun Yeong Choe*, Jae Won Hong, Dong Yeob Shin, Bong Soo Cha, Hyun Chul Lee, Byung-Wan Lee Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Republic of Korea 새롭게 진단받은 제2형 당뇨병 환자에서 고혈압유무에 따른 나트륨섭취 현황 및 급원식품에 관한 조사 안희정 1 *, 석희금 1, 이재혁 2, 박강서 2, 한경아 2, 이홍규 2, 민경완 2, 장진영 1 을지병원 당뇨병센터 1, 을지의대 내과 2 Fulminant diabetes in pregnant woman as initial manifestation of autoimmune hypoglycemia 김은영 1 *, 정인경 1, 김세연 1, 김현수 1, 황유철 1, 안규정 1, 정호연 1, 전 숙 2, 오승준 2, 우정택 2, 김성운 2, 김진우 2, 김영설 2 강동 경희대병원 내분비 대사 내과 1, 경희의료원 내분비 대사 내과 2 Efficacy and safety of a fixed dose combination of glimepiride and metformin versus glimepiride when added in to insulin glargine in patients with type 2 diabetes Sun Hyun Park 1 *, Sang Jin Kim 2, Sung Wan Chun 2, Keun Young Park 3, Dong Mee Lim 3, Jong Min Lee 4, Jae Hyuk Lee 1, Jae Min Lee 1, Kang Seo Park 1 Department of Internal Medicine, Eulji University Hospital 1, Soonchunhyang University Cheonan Hospital 2, Konyang University Hospital 3, The Catholic University of Korea, Daejeon ST.Mary's Hospital 4 Impact of visceral obesity on cardiac autonomic neuropathy in T2DM Eun Hee Jang 1 *, Yong Moon Park 2, Na Young Kim 1, Mee Kyoung Kim 1, Ki Hyun Baek 1, Ki Ho Song 1, Kwang Woo Lee 1, Hyuk Sang Kwon 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea 1, Department of Preventive Medicine, The Catholic University of Korea, Seoul, Korea 2 신기능 저하 환자에서 acarbose의 안전성 온정헌*, 구보경, 김상완, 김영기, 박경선, 문민경 서울대학교 의과대학 내과학교실 보라매병원 내분비대사내과 당뇨병 치료 중에 진단 된 클라인펠터증후군 3예 박주리*, 유형준, 최문기, 임성희, 유재명, 홍은경, 이성진, 류옥현, 김철식, 강준구, 유성훈, 김두만 한림대학교의료원

18 P75 P76 P77 P78 P79 P80 P81 P82 P83 P84 P85 P86 P87 Spontaneous hypoglycemia after improvement of DKA in a patient with insulin antibody Yeong Geol Jo*, Ki Won Kim, Hee Ja Ko, Bo Yeon Kim, Chan Hee Jung, Sung Wan Jeon, Ji Oh Mok, Hyeong Kyu Park, Chul Hee Kim, Sang Jin Kim, Dong Won Byun, Kyo Il Suh, Myung Hi Yoo, Sung Gu Kang, Yeo Joo Kim Department of Internal Medicine, University of SoonChunHyang College of Medicine, Cheonan, Korea Study on anti-diabetic effect of combination extracts of Coptidis rhizoma and Salvia miltorrhiza in streptozotocin-induced diabetic rats Yunkyung Han*, Anna Lee, Yongki Park Department of Herbology, College of Oriental Medicine, Dongguk University 불량한 혈당조절을 보이는 2형 당뇨병환자에서 세가지 경구혈당강하제 이용한 치료 정수진*, 김종화 세종병원 Comparisons of vildagliptin-meformin vs. glimepiride-metformin treatments in type 2 diabetic patients 전현정*, 오태근 충북대학교 의과대학 내과학교실 인슐린 자가면역 증후군에 의한 저혈당 환자 8예 임상상 김세원*, 김혜정, 손서영, 배지철, 허규연, 정재훈, 민용기, 이명식, 이문규, 김광원, 김재현 성균관대학교 의과대학 삼성서울병원 내분비대사내과 Analysis of clinical factors influencing C-peptide decline 신미선 1 *, 이우제 1, 김민선 1, 송기호 2, 박중열 1 서울아산병원 내분비내과 1, 건국대학교 내분비내과 2 2형 당뇨 환자의 지속형 인슐린 병용 사용과 혈당 변동 유승현*, 박철영 성균관의대 강북삼성병원 내분비내과 제 2형 당뇨병 환자에서 ezetimibe와 simvastatin 단기 병용 치료 후 치료 목표 도달율에 대한 관찰 박수경 1 *, 박소영 1, 이혜정 2, 김덕규 1, 박미경 1 동아대학교 의과대학 내과학교실 1, 동아대학교 의과대학 약리학교실 2 Association between body mass index, insulin resistance, and pancreatic β-cell function in newly-presenting type 2 diabetic patients 정진욱*, 이두영, 문중식, 조동혁, 정동진, 정민영 전남의대 내과학교실 Serum vitamin D status and its relationship with metabolic parameters in patients with type 2 diabetes mellitus Jung-Re Yu 1 *, Jae-Geun Lee 1, Sung-Hyun Kim 1, Mi-Hee Kong 2, Gwanpyo Koh 1, Sang Ah Lee 1, Keun-Young Park 3, Byung-Joon Kim 3, Dong-Mee Lim 3, Dae Ho Lee 1 Department of Internal Medicine, Jeju National University School of Medicine and Jeju National University Hospital, Jeju 1, Department of Family Medicine, Jeju National University School of Medicine, Jeju 2, Department of Internal Medicine, Konyang University School of Medicine, Daejeon 3 Effect of glucokinase activator on glucose metabolism in mouse primary hepatocyte Eun Young Park*, Eung Hwi Kim, Hee Sook Jun Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea 응급실 내원 시 저혈당을 보이는 당뇨병 환자에서 예후인자에 대한 연구 김희경*, 김수정, 윤지희, 박상우, 문중식, 강호철 전남의대 화순전남대병원 내과 계절적 요인에 의한 혈당조절의 차이에 대한 연구 유경화*, 오인명, 김용현 분당제생병원

19 P88 P89 P90 P91 P92 P93 The determinants of the brachial-ankle pulse wave velocity in normotensive young adults with type 2 diabetes Bo Gwang Choi 1 *, Ji Hyun Kang 1, Mi Ra Kim 1, Yun Kyung Jeon 1, Sang Soo Kim 1, Bo Hyun Kim 1, Chang Won Lee 2, Yong Ki Kim 3, In Joo Kim 1 Department of Internal Medicine, School of Medicine, Pusan National University 1, Department of Internal Medicine, Busan St. Mary s Hospital 2, Kim Young Ki Internal Medicine Clinic 3 Synergistic weight loss and diabetes improvement with exenatide administration after laparoscopic gastric banding - case report - 김경욱*, 남지선, 강신애, 박종숙, 안철우, 차봉수, 김경래, 이현철 연세의대 내과학교실 내분비내과 The short-term influence of weight loss on metabolic profiles and cardiovascular risk in obese Korean patients with type 2 diabetes 홍은경*, 이신애, 이미희, 이영란, 장 미, 김준영, 박선아, 정지영, 김지연 한림의대 강남성심병원 Effect of Sitagliptin on beta cell and alpha cell function in type 2 diabetic patients 장진선*, 신정아, 조재형 가톨릭대학교 서울성모병원 내분비내과 Efficacy of Exenatide in clinical practice in Korean type 2 diabetic patient 장진선*, 신주영, 김경희, 조재형 가톨릭대학교 서울성모병원 내분비내과 2형 당뇨병환자에서 DPP-4 저해제(sitagliptin)와 설폰 요소제(glimepiride) 치료군 간의 혈관경직도의 변화 비교 연구 최영주 1 *, 김철식 2, 박석원 3, 이은직 4, 허갑범 1 허내과 1, 한림대학교 2, CHA의과학대학교 3, 연세대학교 4 Acute & chronic complication 305 P94* Effects of ferulic acid on diabetic nephropathy in type 2 diabetic rat model Eun Soo Lee 1 *, Ran Choi 1, Mi Young Lee 1, Bo Hwan Kim 2, Jarinyaporn Naowaboot 1, Eun Ju Cho 1, Eun Young Lee 3, Young Chul Yang 4, Choon Hee Chung 1 Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea 1, Department of Nursing, Gachon University of Medicine and Science, Incheon, Korea 2, Department of Internal Medicine, Soon Chun Hyang University College of Medicine, Cheonan, Korea 3, Department of Anatomy, Yonsei University Wonju College of Medicine, Wonju, Korea 4 P95* Vascular inflammation stratified by C-reactive protein and LDL-cholesterol levels: analysis with 18F-fluorodeoxyglucose positron emission tomography Hye Jin Yoo 1 *, Sungeun Kim 2, Ho Cheol Hong 1, Hae Yoon Choi 1, Sae Jeong Yang 1, Ji A Seo 1, Sin Gon Kim 1, Nan Hee Kim 1, Sei Hyun Baik 1, Dong Seop Choi 1, Kyung Mook Choi 1 Divisions of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea 1, Department of Nuclear Medicine, Korea University College of Medicine, Seoul, Korea 2 P96* 제2형 당뇨병 환자에서 신기능 저하를 예측할 수 인자로서 소변 cystatin C 강지현 1 *, 최보광 1, 김미라 1, 전윤경 1, 김상수 1, 김보현 1, 김용기 2, 김인주 1 부산대학교 내분비대사내과 1, 김용기내과 2 P97* Detection of albuminuria aggravation in diabetic patients by serial measurements of serum cystatin C concentration Shinyoung Lee*, Jeong Seon Yoo, Eun Hae Lee, Eun Hae Lee, Youngmi Lee, Youngmi Lee, Jong Suk Park, Kyung Rae Kim, Chul Woo Ahn Gangnam Severance Hospital of Yonsei University Department of Internal Medicine, Seoul, Korea

20 P98* Increased aortic pulse wave velocity is associated with postprandial triglyceride after mixed meal test in type 2 diabetic patients Eun Young Lee 1 *, Sang Hoon Shin 2, Hyuk-Jae Chang 2, Byung-Wan Lee 1, Eun Seok Kang 1, Bong-Soo Cha 1, Hyun Chul Lee 1, Kwang Joon Kim 3 Division of Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine 1, Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine 2, Severance Hospital Executive Health Promotion Center 3 P99* Serum gamma-glutamyltransferase is associated with arterial stiffness in healthy individuals Chang Hee Jung 1 *, Ji Hee Yu 1, Yoonoo Hwang 1, Sung Jin Bae 2, Eun Hee Koh 1, Min-Seon Kim 1, Joong-Yeol Park 1, Hong-Kyu Kim 2, Woo Je Lee 1 Department of Internal Medicine 1, Department of Health Screening and Promotion Center, University of Ulsan College of Medicine, Asan Medical Center 2 P100* Elevated serum ceruloplasmin levels are associated with albuminuria in Korean men with type 2 diabetes mellitus Chang Hee Jung*, Woo Je Lee, Ji Hee Yu, Ji Hye Yim, Eun Hee Koh, Min-Seon Kim, Joong-Yeol Park Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center P101* Factors associated with aortic knob calcification in type 2 diabetics without chronic renal failure 노혜정*, 유태양, 김하영, 박병현, 조정구 원광대학교 의과대학 내분비대사내과 P102 P103 P104 P105 P106 P107 P108 P109 Serum cystatin C as well as urinary albumin-creatinine ratio is associated with carotid intima-media thickness (IMT) in Korean type 2 diabetic patients Kyung Sun Park*, Hyun Ju Oh, Seok Won Park, Yong Wook Cho, Soo Kyung Kim Department of Internal Medicine, CHA Bundang Medical Center, CHA University Increased EPCs level can help the clinical decision on coronary intervention in asymptomatic type 2 diabetic subjects with abnormal finding in cardiac MRI Hyun Min Kim*, Jae Hoon Moon, Min Kyung Chae, Jung Soo Lim, Bong Soo Cha, Hyun Chul Lee, Byung-Wan Lee Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine The relationship of gamma-glutamyltransferase to adiponectin and arterial stiffness Youngmi Lee*, Ji Woon Kim, Shinyoung Lee, Eun Hae Lee, Jeong Seon Yoo, Shin Ae Kang, Chul Woo Ahn, Kyung Rae Kim, Jong Suk Park Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 갑상선 중독증을 동반한 당뇨병성케톤산증 1예 김재현*, 박선만, 김영진, 강동현, 김명숙, 임성희, 최문기, 유형준, 유성훈 한림대학교 의과대학 내과학교실 Association between cardiac autonomic neuropathy, diabetic retinopathy, kidney function by estimated GFR and carotid atherosclerosis in type 2 diabetic patients 정찬희*, 김보연, 김철희, 강성구, 목지오 순천향대학교 부천병원 내분비내과 Long-term effects on fat accumulation and metabolic changes in response to ionizing radiation Moon Ki Hong*, Min-Kyoung Park, Hae-Ran Park, Uhee Jung, Sung-Kee Jo, Changhyun Roh Korea Atomic Energy Research Institute A case of shoulder tuberculosis with diabetes Moon Ki Hong*, Jae Woong Kim, Seong Hyeop Hyeon, Mi Yi Kim, Seok Hong Lee, Jaetaek Kim, Jihyun Ahn Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Korea 당뇨병성 말초신경병증이 균형능력에 미치는 영향 문정화 1 *, 임길병 2, 김영섭 2, 김동준 3, 노정현 3 인제대학교 일산백병원 스포츠건강의학센터 1, 인제대학교 일산백병원 재활의학과 2, 인제대학교 일산백병원 내분비대사내과 3

21 P110 P111 당뇨병성 망막증의 기왕력이 없는 당뇨병 환자에서 무산동 안저 촬영에 의한 망막병증의 선별검사 최보광 1 *, 강지현 1, 김미라 1, 전윤경 1, 김상수 1, 김보현 1, 김용기 2, 김인주 1 부산대학교병원 1, 김용기내과 2 한국인 당뇨병의 혈당조절과 미세혈관합병증의 관계 김대중 1 *, 김철식 2, 박석원 3, 이은직 4, 최영주 5, 허갑범 5 아주의대 1, 한림의대 2, CHA의과학대 3, 연세의대 4, 허내과 5 Epidemiology & genetics 314 P112* A genome-wide association study of gestational diabetes mellitus in Koreans Soo Heon Kwak 1 *, Young Min Cho 1, Sung-Hoon Kim 2, Hyoung Doo Shin 3, Nam H. Cho 4, Hyung-Lae Kim 5, In Kyu Lee 6, Hyung Jin Choi 1, Hak C. Jang 1, Seong Yeon Kim 1, Kyong Soo Park 1 Department of Internal Medicine, Seoul National University College of Medicine 1, Department of Internal Medicine, Kwandong University College of Medicine 2, Department of Life Science, Sogang University 3, Department of Preventive Medicine, Ajou University School of Medicine 4, Center for Genome Science, Korea National Institute of Health 5, Department of Internal Medicine, Kyungpook National University School of Medicine 6 P113* Genome analysis of cybrids carrying mitochondrial DNA 3243A>G mutation Byung Yong Ahn 1 *, Sehyun Chae 2, Kyunghee Byun 3, Bonghee Lee 3, Young Min Cho 1, Myeong-Hee Yu 4, Daehee Hwang 2, Kyong Soo Park 1 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea 1, School of Interdisciplinary Bioscience and Bioengineering, POSTECH, Pohang, Korea 2, Center for Genomics and Proteomics & Stem Cell Core Facility, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea 3, Functional Proteomics Center, Korea Institute of Science and Technology, Seoul, Korea 4 P114* Effect of sarcopenic obesity on functional limitations in older Korean people: the Korean Longitudinal Study on Health and Aging (KLoSHA) Jung Hee Kim 1 *, Soo Lim 1, Sung Hee Choi 1, Ji Won Yoon 1, Ji Won Yoo n, MD 1,2, Seon Mee Kang 1, Ju Hee Lee 1, Jung Ah Lim 1, Young Joo Park 1, Ki Woong Kim 2, Kyong Soo Park 1, Hak Chul Jang 1 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea 1, Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Korea 2 P115* Vitamin D status is more closely associated with visceral obesity than sarcopenia in elderly Koreans; Ansan geriatric study 서지아*, 은채령, 조현주, 홍호철, 김윤정, 조명진, 최혜윤, 김주형, 양세정, 류혜진, 김희영, 김신곤, 최경묵, 백세현, 최동섭, 김난희 Division of Endocrinology, Department of Internal Medicine, Korea University Medical College P116* 국내 당뇨병 환자의 고혈압 profile을 통한 고혈압 유병율 및 관리 실태의 이해 서미혜 1 *, 박철영 1, 오기원 1, 이원영 1, 박세은 1, 최지훈 1, 원희관 1, 전원선 1, 이문규 2, 박중열 3, 이우제 3, 김성래 5, 윤건호 4, 박성우 1 성균관대학교 의과대학 강북삼성병원 내분비대사 내과 1, 성균관대학교 의과대학 삼성서울병원 내분비대사 내과 2, 울산대 학교 의과대학 서울아산병원 내분비대사 내과 3, 가톨릭대학교 의과대학 서울성모병원 내분비내과 4, 가톨릭대학교 의과대 학 부천성모병원 내분비대사 내과 5 P117* No effect of mild renal dysfunction on serum 1,5-anhydroglucitol concentrations in type 2 diabetic patients 김원준*, 원희관, 박세은, 이은정, 이원영, 오기원, 박성우, 김선우, 박철영 Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine P118* Diabetic patient s LDL-C target goal achievement (DART research) 전원선 1 *, 박철영 1, 박세은 1, 이은정 1, 오기원 1, 이원영 1, 김선우 1, 박중열 2, 이우제 2, 이문규 3, 윤건호 4, 김성래 5, 박성우 1 성균관의대 강북삼성병원 내분비내과 1, 울산의대 서울아산병원 내분비내과 2, 성균관의대 삼성서울병원 내분비내과 3, 가 톨릭의대 서울성모병원 내분비내과 4, 가톨릭의대 부천성모병원 내분비내과 5 P119 The first Vietnamese case of fulminant type 1 diabetes 정태식*, 김희진, 김수경, 정순일, 정정화, 이상민, 함종렬 경상대학교 의학전문대학원 내과

22 P120 P121 성인에서 염증인자와 심혈관질환 위험요소 및 대사증후군과의 상관관계 이상준*, 배학연, 신지혜, 김진화 조선대학교병원 내분비 대사내과 Relationship of 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase gene polymorphisms with metabolic syndrome and type 2 diabetes Seong Su Moon 1 *, Young Sil Lee 1, Jung Guk Kim 2, Ji Yun Jeong 2, Eon Ju Jeon 2, Hyun Ae Seo 2, In Kyu Lee 2 Department of Internal Medicine, Dongguk University School of Medicine 1, Department of Endocrinology and Metabolism, Kyungpook National University Hospital 2 P122 Increasing prevalence of gestational diabetes mellitus in Korean women from 2003 to 2009 Hee-Sook Kim 2 *, Jeong-Eun Park 1, Sung-Hoon Kim 1 Division of Endocrinology & Metabolism, Department of Medicine, Cheil General Hospital & Women s Healthcare Center, Kwandong University College of Medicine, Seoul, Korea 1, College of Nursing, Seoul National University, Seoul, Korea 2 P123 P124 P125 P126 P127 P128 P129 P130 중환자실 환자의 혈당이 예후에 미치는 영향 정현희*, 박상현, 박병삼, 원규장, 윤지성, 이형우 영남대학교 의과대학 내과학교실 신세포암과 동반된 인슐린종 1예 박상현*, 윤지성, 정현희, 이형우, 원규장 영남대학교 의과대학 내과학교실 좌측 신장 무형성과 척추기형을 동반한 선천적 등쪽 췌장 발육 부전증 1예 류아정*, 문현진, 김동순, 고봉석, 이재민, 이재혁, 박강서 대전 을지대학병원 내분비대사 내과 한국인 당뇨병의 인슐린 분비능과 저항성에 따른 분류와 임상 및 생화학적 특성 김철식 1 *, 김대중 2, 박석원 3, 이은직 4, 최영주 5, 허갑범 5 한림의대 1, 아주의대 2, CHA의과학대 3, 연세의대 4, 허내과 5 The effect of menopause on metabolically obese but normal weight (MONW) and metabolically healthy but obese (MHO) women in Korea Jin-Young Choi 1 *, Hee-Sung Ha 2, Hyuk-Sang Kwon 3, Seung-Hwan Lee 3, Hyun-Hee Cho 4, Hyeon-Woo Yim 2, Won-Chul Lee 2, Yong-Moon Park 2 College of Medicine, The Catholic University of Korea, Seoul, Korea 1, Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea 2, Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea 3, Department of Obstetrics and Gynecology, College of Medicine,The Catholic University of Korea, Seoul, Korea 4 Change of management status in Korean type 2 diabetic patients: 3-year follow-up of Korean type 2 diabetes prospective cohort study Moon Chan Choi 1 *, Sang Ouk Chin 1, Sang Youl Rhee 1, Suk Chon 1, Seungjoon Oh 1, Jeong-taek Woo 1, Sung-Woon Kim 1, Jin-Woo Kim 1, Sei Hyun Baik 2, Yong Soo Park 3, Moon Suk Nam 4, Kwan Woo Lee 5, Young Seol Kim 1 Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine 1, Department of Endocrinology and Metabolism, Korea University College of Medicine 2, Department of Endocrinology and Metabolism, Hanyang University College of Medicine 3, Department of Endocrinology and Metabolism, Inha University College of Medicine 4, Department of Endocrinology and Metabolism, Ajou University School of Medicine 5 당뇨병 발생 예측인자로서의 incretin hormone 김미연 1 *, 손서영 1, 허규연 1, 김재현 1, 조남한 2, 이문규 1 성균관대학교 의과대학 삼성서울병원 내분비-대사내과 1, 아주대학교 의과대학 임상역학센터 2 A decision tree-based approach for identifying urban-rural differences of risk factors of metabolic syndrome in adult Korean population Tae Nyun Kim 1 *, Man Sik Park 2, Seong Keon Lee 2, Jung Min Kim 3, Jong Chul Won 3, Kyung Soo Ko 3, Byoung Doo Rhee 3 Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan 1, Department of Statistics, College of Natural Sciences, Sungshin Women s University, Seoul 2, Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea 3