[17].,,, [18,19].. Bakhsh [20], Sklan [21] Dawa [22], Kendler[18]. Makheja [23] Srivastava[24] thromboxane. Hughes [25], Dorsch [26]. Jurdi-Haldeman [
|
|
|
- 영유 원
- 6 years ago
- Views:
Transcription
1 임선영한국해양대학교해양환경생명과학부 1. (Allium cepa L.),,,, [1], [2-4], [5], [6], [7,8], [9], [10], [11].,,,, [12]. (polyphenol), C, E, - quercetin, quercitrin, rutin. diphenlypropane(c 6 -C 3 -C 6 ),,,, [13], Miean Mohamed[14] 62. hydroxylation, glycosylation,,,, 5,000 [15]..,,,,,. ally propyl disulfide dially disulfide quercetin, isorhamnetin, kaempferol, rutin [5,16]. 377
2 [17].,,, [18,19].. Bakhsh [20], Sklan [21] Dawa [22], Kendler[18]. Makheja [23] Srivastava[24] thromboxane. Hughes [25], Dorsch [26]. Jurdi-Haldeman [27].,. Woo [28],, Kim Lee[3],, LDL- HDL-,. 60g [29]. 50g., [30~32].,,, [33].,,, Kim [34] 378
3 , 13.29% 12.99% 10.78%. C, > >. [34,35].. [36,37]. 10% 10%. quercetin quercetin 0.01%, 6.5% [12]. 0.4~0.5%, 25~32% 50 [45] 재료및추출. (STVD-50, Sanya, Korea) 15~25, 15~40 mmhg
4 acetone methylene chloride 1 : rotary vacuum evaporator(n-1000, EYELA, Japan) aceton/methylene chloride (A+M). A+M methanol 2 methanol (MeOH). hexane, 85% aq. MeOH, butanol(buoh), water. dimethyl sulfoxide (DMSO). DMSO 0.05%. 2.2 일반성분및비타민 C 측정,,, AOAC [38]., (105 ), Kjeldahl, Soxhlet, 550. C HPLC(P580, Dionex, USA) [39]. 1g, 10% HPO 3 9ml 3,000rpm 15 20L HPLC C. column (u-bondapak C 18 ), 0.05M KH 2 PO 4 / acetonitrile(60 : 40) 1ml/min UV/VIS detector 254nm. L-ascorbic acid(sigma-adrich, USA). 2.3 총플라보노이드측정 1ml 10ml diethyleneglycol 1N NaOH 1ml 37 1 UV-visible spectrophotometer(helios Beta, Thermo Electron Corporation, USA) 420nm. rutin [38]. 2.4 총페놀측정 Folin-Denies [40]. 380
5 1mg 1ml 10 2ml 2 Folin 2ml 3 10% Na 2 CO 3 2ml 1. UV-visible spectrophotometer(helios Beta, Thermo Electron Corporation, USA) 750nm. tannic acid(sigma-aldrich, USA). 2.5 유리아미노산비교분석 10g 75% 100ml 80, M sodium citrate buffer(ph 2.2)(Merck, Germany) 5ml Sep-Pak C M membrane filter [41]. 2.6 색도측정 (CR-10, Konica Minolta Sensing, Inc., Japan), 3 total color difference(e) [42]. 2.7 암세포및암세포배양 () (HT-1080), (AGS) (HT-29). 100units/ml penicillin-streptomycin 10% FBS DMEM RPMI , 5% CO 2 incubator(mco-15ac, Sanyo Electric Biomedical Co., Japan). 2. phosphate buffered saline(pbs) 0.05% trypsin-0.02% EDTA(Gibco Co., USA) 75mm 3 cell culture flask 10ml 6~ MTT assay 96 well cell culture plate cells/ml 100L 37, 5% 381
6 CO 2 incubator 24 well 100L, PBS 100L. plate 37, 5% CO 2 incubator 24. MTT assay 3-(4,5-dimethylthiazol)-2,5- diphenyltetrazolium bromide(mtt) 5mg 1ml PBS, 10% FBS 9ml 100L 3~4 MTT. formazan well MTT. well formazan DMSO 100L 5~10 microplate reader(victor3, Perkin Elmer, USA) 540nm. MTT, well [43]. 2.9 세포내활성산소종 (reactive oxygen species) 측정 HT units/ml penicillin-streptomycin 10% FBS DMEM cell culture dish 37, 5% CO 2 incubator. DCFH-DA(dichlorodihydrofluorescin diacetate) assay [44]. DCFH-DA(Sigma- Aldrich, USA) (dichlorofluorescein, DCF). 96 well cell culture plate 24, PBS 20M DCFH-DA well 37, 5% CO 2 incubator 20 pre-incubation. well 37, 5% CO 2 incubator 1, DCFH-DA PBS 500M H 2 O 2 DCF fluorescence excitation 488nm, emission 530nm microplate reader(victor3, Perkin Elmer, USA). (blank control) PBS, control 500M H 2 O 2, blank 500M H 2 O 2 PBS. 382
7 저온진공건조된양파분말의화학성분및생리활성 C C % 7.15%. C, 6.27mg/100g 17.34mg/100g 9.55mg/100g. 1 Chemical composition of onion powder as affected by drying methods Components Raw Vacuum drying Freeze drying Moisture (%) Carbohydrate (%) Crude protein (%) Crude fat (%) Crude ash (%) Vitamin C (mg/100 g) phosphoethanolamine, L-aspartic acid, L-glutamic acid, L-alanine, L-citrulline, -aminobutryric acid. phosphoserine, phosphoethanolamine, L-valine, L-isoleucine. 383
8 2 Free amino acid contents of onion powder by different drying methods (ppm in sample) Amino acids Raw Vacuum drying Freeze drying Phosphoserine Taurine Phosphoethanolamine , ,588.3 Urea L-Aspartic acid ,060.3 L-Threonine L-Serine Asparagine L-Glutamic acid ,578.5 L--Aminoadipic acid L-Proline L-Glycine L-Alanine , ,003.8 L-Citrulline , L--Aminobutric acid L-Valine , L-Cystine L-Methionine L-Isoleucine L-Leucine L-Tyrosine L-Phenylalanine Alanine Aminobutyric acid Aminobutyric acid 2, , ,412.0 NH L-Orinithine L-Lysine Mothyl-L-Histidine L-Histidine Methyl-L-Histidine L-Carnosine L-Arginine Total 4, , ,
9 3. Hunter-L > >. Hunter-a Hunter-b > >. 3 Color of onion powder as affected by drying methods Color Raw Vacuum drying Freeze drying L-value a-value b-value , C 4,. 93.1% 14.3% %, %. C, 6.27mg/100g g/ml. 4 Chemical composition of onion flesh and peel Components Onion flesh Onion peel Moisture (%) Carbohydrate (%) Crude protein (%) Crude fat (%) Crude ash (%) Vitamin C (mg/100 g) Total flavonoids (g/ml) A+M MeOH 0.05mg/ml HT M H 2 O 2 control 385
10 120, A+M ( 1). 2 hexane, 85% aq. MeOH, butanol(buoh), water 0.05mg/ml control. ( 2A), 85% aq. MeOH BuOH hexane water control. ( 2B) 85% aq. MeOH hexane water contorl. A+M 85% aq MeOH BuOH. Ra [5] butanol> ethyl acetate> ethyl ether> water. Kim Kim[45], 100,, 1 Inhibitory effect of acetone/methylene chloride (A+M, 0.05mg/ml) and methanol (MeOH, 0.05mg/ml) extracts of onion flesh and peel on production of cellular reactive oxygen species in HT-1080 cells. Control was treated with 500M H 2 O 2 and phosphate buffered saline. Blank was treated with phosphate buffered saline without H 2 O
11 2 Inhibitory effect of solvent fractions (0.05mg/ml, A; Onion peel: B; Onion flesh) of extracts from onion flesh and peel on production of cellular reactive oxygen species in HT-1080 cells. Control was treated with 500M H 2 O 2 and phosphate buffered saline. Blank was treated with phosphate buffered saline without H 2 O 2..,, 387
12 . LDL thiobarbituric acid reactive substances(tbars) LDL TBARS scavanger quercetin LDL. Park Kim[46] 5% TBARS quercitin. Shon [47] -carotene-linoleate system BHT L-ascorbic acid. MTT assay. 3 acetone/methylene chloride (A+M) methanol (MeOH) 0.1, 0.5 1mg/ml AGS. A+M 0.1mg/ml 3 Inhibitory effect of acetone/methylene chloride (A+M) and methanol (MeOH) extracts from onion flesh and peel on the growth of AGS human gastric adenocarcinoma cells. *p<0.05, significantly different from control. #p<0.05, significant effect between onion flesh and peel. 388
13 AGS 0.5mg/ml 95%, 1mg/ml 96% (p<0.05). A+M A+M 1mg/ml 13%. MeOH A+M 1mg/ml 23 35%. 4 hexane, 85% aq. MeOH, BuOH, water 4 Inhibitory effect of solvent fractions of extracts from onion flesh and peel on the growth of AGS human gastric adenocarcinoma cells. *p<0.05, significantly different from control. #p<0.05, significant effect between onion flesh and peel. 389
14 5 Inhibitory effect of acetone/methylene chloride (A+M) and methanol (MeOH) extracts from onion flesh and peel on the growth of HT-29 human colon cancer cells. * p<0.05, significantly different from control. # p<0.05, significant effect between onion flesh and peel. 85% aq. MeOH 0.5mg/ml 90% (p<0.05). HT-29 ( 5), AGS A+M 0.5 1mg/ml 90% MeOH AGS 1mg/ml 44%. A+M MeOH 1mg/ml 28 21%. 6 hexane, 85% aq. MeOH, BuOH, water HT-29 85% aq. MeOH (p<0.05). 85% aq. MeOH 0.5mg/ml 93% BuOH 46 42% (p<0.05). 5 IC 50 A+M IC 50 AGS HT mg/ml MeOH IC mg/ml AGS. 85% aq. MeOH AGS IC mg/ml 390
15 . HT-29 AGS. water. A+M MeOH. Lee [19] Inhibitory effect of solvent fractions of extracts from onion flesh and peel on the growth of HT-29 human colon cancer cells. *p<0.05, significantly different from control. #p<0.05, significant effect between onion flesh and peel. 391
16 25 50mg %, quercitin, detoxification enzyme. Dorant [48] allicin, Sankaranrayanan [49] case-control. AGS. 85% aq. MeOH. 5 IC50 values of onion flesh and peel extracts on human cancer cell lines IC 50 Concentrations (mg/ml) AGS HT-29 A+M extract Flesh Peel MeOH extract Flesh Peel Hexane fraction Flesh Peel % aq. MeOH fraction Flesh Peel BuOH fraction Flesh Peel Water fraction Flesh Peel
17 3.1 건조붉은양파의화학성분및생리활성, C 17.95% 80% ( 6).,, 62.96, 8.74, %. C, 15mg/100g 96mg/100g. (34.29mg/ml) 39.05mg/ml. 6 Chemical composition of red onion Flesh red onion Dried red onion Moisture (%) ) Carbohydrate (%) Crude protein (%) Crude fat (%) Crude ash (%) Vitamin C (mg/100 g) Total phenol (mg/ml) ) Values are Mean S.E. 7 L-aspartic acid, L-glutamic acid, L-alanine, L-leucine, -aminobutryric acid. phosphoserine, phosphoethanolamine, L-aspartic acid, L-alarine, L-citrulline, L-valine, L-leucine, L-phenylalanine, -aminobutryric acid, L-histidine. 393
18 7 Free amino acid contents of red onion (ppm in sample) Amino acids Raw Vacuum drying Phosphoserine Taurine - - Phosphoethanolamine ,343.2 Urea - - L-Aspartic acid L-Threonine L-Serine Asparagine - - L-Glutamic acid L--Aminoadipic acid - - L-Proline - - L-Glycine L-Alanine ,184.7 L-Citrulline L--Aminobutric acid - - L-Valine L-Cystine - - L-Methionine - - L-Isoleucine L-Leucine L-Tyrosine L-Phenylalanine Alanine - - -Aminobutyric acid - - -Aminobutyric acid 3, ,479.9 NH L-Orinithine - - L-Lysine Mothyl-L-Histidine - - L-Histidine Methyl-L-Histidine - - L-Carnosine - - L-Arginine - - Total 4, ,
19 8. Hunter-L Hunter-b. Hunter-a Color of red onion powder Color Raw Vacuum drying L-value a-value b-value acetone/methylene chloride (A+M) methanol (MeOH) 0.1 5mg/ml HT A+M 0.25mg/ml HT mg/ml 96%, 5mg/ml 98% 9 Inhibitory effect of acetone/methylene chloride (A+M) and methanol (MeOH) extracts of red onion powder on the growth of HT-1080 human fibrosarcoma cells Treatments A+M extract MeOH extract *p<0.05, significantly different from control. Concentration Inhibition IC 50 (mg/ml) (%) (mg/ml) * * * 5 98* * 5 50* 10 89*
20 (p<0.05). MeOH, MeOH 5 10mg/ml 50 89% (p<0.05). A+M MeOH IC mg/ml A+M MeOH. hexane, 85% aq. MeOH, butanol(buoh), water HT-1080 ( 10), 5mg/ml water 86% 10 Inhibitory effect of solvent fractions of extract from red onion powder on the growth of HT-1080 human fibrosarcoma cells Treatment Hexane fraction 85% aq. MeOH fraction BuOH fraction Water fraction *p<0.05, significantly different from control. Concentration Inhibition IC 50 (mg/ml) (%) (mg/ml) * * * * 5 93* 10 98* * 5 86* 10 98* * 5 94* 10 97* * * * 5 43* 10 86*
21 (p<0.05), hexane IC mg/ml. 11 HT-29, HT-1080 A+M MeOH HT mg/ml A+M 91 97% (p<0.05), IC mg/ml. MeOH 5 10mg/ml 58, 70% IC mg/ ml HT-29 A+M (p<0.05). 12 hexane, 85% aq. MeOH, BuOH, water HT-1080 water 5mg/ml 88%. hexane 85% aq. MeOH IC mg/ml. HT-1080 HT-29 A+M MeOH. water HT-1080 HT-29. Rho Han[6] NCI-H522 NCI-H596 NCI-H522 48%, NCI-H596 25% NCI-H596, Lee 11 Inhibitory effect of acetone/methylene chloride (A+M) and methanol (MeOH) extracts of red onion powder on the growth of HT-29 human colon cancer cells Treatments A+M extract MeOH extract *p<0.05, significantly different from control. Concentration Inhibition IC 50 (mg/ml) (%) (mg/ml) * * * * 5 97* * * * * 5 58* 10 70*
22 [19] 20mg 55%, 25 50mg 32 34%. 12 Inhibitory effect of solvent fractions of extract from red onion powder on the growth of HT-29 human colon cancer cells Treatments Hexane fraction 85% aq. MeOH fraction BuOH fraction Water fraction *p<0.05, significantly different from control. Concentration Inhibition IC 50 (mg/ml) (%) (mg/ml) * * * * 5 98* 10 99* * * * * 5 88* 10 87* * * * * 5 95* 10 94* * * * * 5 52* 10 84*
23 A+M MeOH mg/ml HT A+M MeOH 500M H 2 O 2 control 120. hexane, 85% aq. MeOH, BuOH, water 8 HT mg/ ml 85% aq. MeOH. water. A+M, MeOH. Shon Park[50],. Shahidi Wanasundara[51] phenolic hydroxyl groups. Shon [47], 2. Jeong [52] C mg/100g C C. C. Kim [53] -carotene-linoleate system butylated hydroxy toluene(bht) L-ascorbic acid. 20~30%, FRAP(Ferric reducing ability of plasma), [54]. in vitro in vivo thiobarbituric acid reactive 399
24 7 Inhibitory effect of extracts of red onion powder on production of reactive oxygen species in HT-1080 cells. 1) Control was treated with 500M H 2 O 2 and phosphate buffered saline. 2) Blank was treated with phosphate buffered saline without H 2 O 2. 3) A+M 0.01, acetone with methylene chloride extract 0.01mg/ml; MeOH 0.01, methanol extract 0.01mg/ml (A). 4) A+M 0.05, acetone with methylene chloride extract 0.05mg/ml; MeOH 0.05, methanol extract 0.05mg/ml (B). 400
25 8 Inhibitory effect of solvent fractions of red onion powder on production of cellular reactive oxygen species in HT-1080 cells. 1) Control was treated with 500M H 2 O 2 and phosphate buffered saline. 2) Blank was treated with phosphate buffered saline without H 2 O 2. 3) Hexane 0.01, hexane fraction 0.01mg/ml; 85% aq. MeOH 0.01, 85% aqueous methanol fraction 0.01mg/ml; BuOH 0.01, butanol fraction 0.01mg/ml; water 0.01, water fraction 0.01mg/ml (A). 4) Hexane 0.05, hexane fraction 0.05mg/ml; 85% aq. MeOH 0.05, 85% aqueous methanol fraction 0.05mg/ml; BuOH 0.05, butanol fraction 0.05mg/ml; water 0.05, water fraction 0.05mg/ml (B). 401
26 substances(tbars) [55] C. 48. A+M MeOH 0.05mg/ml (HT-1080). 85% aq. MeOH BuOH 85% aq. MeOH. A+M MeOH, (HT-29) (AGS). 85% aq. MeOH AGS IC mg/ml. 80% C. HT-1080 HT-29 A+M MeOH, hexane IC mg/ml HT A+M, MeOH, hexane, 85% aq. MeOH, BuOH, water 500M H 2 O 2 control, 120. hexane 402
27 85% aq. MeOH. 5%,.,,,,,. 1) Block, E Antithrombotic organosulfur compounds from garlic. J. Am. Soc. 108, ) Kim, K. M., H. J. Suh, S. H. Chung, W. D. Cho and S. J. Ma Chemical structure of angiotensin converting enzyme inhibitor isolated from onion flesh. Food Sci. Biotechnol. 8, ) Kim, S. O. and M. Y. Lee Effect of ethylacetate fraction of onion on lipid metabolism in high cholesterol fed rats. J. Kor. Soc. Food Sci. Nutr. 30, ) Ma, S. J Inhibitory effect of onion seasoning on angiotensin converting enzyme. J. Kor. Soc. Food Sci. Nutr. 29, ) Ra, K. S., H. J. Suh, S. H. Chung and J. Y. Son Antioxidant activity of solvent extract from onion skin. Kor. J. Food Sci. Technol. 29, ) Rho, S. N. and J. H. Han Cyotoxicity of garlic and onion methanol extract on human lung cancer cell lines. J. Kor. Soc. Food Sci. Nutr. 29, ) Lee, S. H., S. J. Woo, Y. J. Koo and H. K. Shin Effects of mugwort, onion and polygalate radix on the intestinal environment of rats. Kor. J. Food Sci. Technol. 27, ) Rao, R. R., S. S. Rao and P. R. Venkataraman Investigations on plant antibiotics, studies on allicin, the antibacterial principles of Allium sativum L(Garlic). J. Sci. Ind. Res. (India). 18, ) Sheo, H. J., H. J. Lim and D. L. Jung Effect of onion juice on toxicity of lead in rat. J. Kor Soc. Food Sci. Nutr. 22, ) Park, P. S., B. R. Lee and M. Y. Lee Effects of onion diet on carbon tetrachloride toxicity of rats. J. Kor. Food Nutr. 20, ) Park, P. S., B. R. Lee and M. Y. Lee Effects of onion juice on ethanol-induced hepatic lipid peroxidation in rats. J. Kor. Food Nutr. 23, ) Cha, J. Y. and J. Y. Han The antioxidant ability of grape seed extracts. Kor. J. Food Sci. Technol. 34, ) Bravo. L Polyphenols: chemistry, dietary sources, metabolism and nutritional significance. Nutr. Reviews. 51, ) Miean, K. H. and S. Mohamed Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plant. J. Agric. Food Chem. 49, ) Freucenbeim, J. L., J. R. Marshall, J. E. Vena, R. Laughlin, J. R. Brasure, M. K. Swanson, T. Nemoto and S. 403
28 Graham Premenopausal breast cancer risk and intake of vegetables, fruits and realted nutrients. J. Natl. Cancer Inst. 88, ) Bilyk, A., P. I. Cooper and G. M. Sapers Varietal differences in distribution of quercetin and kaempferol in onion (Allium cepa L.) tissue. J. Agric. Food Chem. 32, ) Rhim, J. S Onion and health, International Culture Publishing Co., Korea. pp ) Kendler, B. S Garlic (Allium sativum) and onion (Allium cepa): a review of their relationship to cardiovascular disease. Prev. Med. 16, ) Lee, C. J., H. D. Kim, E. H. Choung, J. K. Suh, C. W. Park and J. K. Ha Reduction effect of carcinogen induced mouse epidermal and forestomach carcinogenesis by the extract of oinon wastes. J. Kor. Soc. Food Sci. Nutr. 29, ) Bakhsh, R. and S. Khan Influence of onion (Allium cepa) and chaunga (Caraluma tubercula) on serum cholesterol, triglycerides, total lipids in human subject. Sarhad J. Agric. 6, ) Sklan, D., Y. N. Bermer and H. Rabinowitch The effect of dietary onion and garlic on hepatic lipid concentrations and activity of antioxidative enzymes in chicks. J. Nutr. Biochem. 3, ) Dawa, F. and P. K. Joseph Toxic effects of excess onion extract in rats. J. Food Sci. Technol. 26, ) Makheja, A. N., J. Y. Vanderhoek and J. M. Bailley Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis. Prostaglandins and Med. USA. 2, ) Srivastava, K. C Onion exerts antiaggregatory effects by altering arachidonic acid metabolism in platelets. Prostaglandins Leukot. Med. 24, ) Hughes, B. G. and L. D. Lawson Antimicrobial effects of Allium sativum L., Allium ampeloprasum L. and Allium cepa L. Phytother. Res. USA. 5, ) Dorsch, W. and H. Wagner New antiasthmatic drugs of plant origin. Immunol. 14, ) Jurdi-Haldeman, D., J. H. MacNeil and D. M. Yared Antioxidant activity of onion and garlic juices in stored cooked ground lamb. J. Food Prot. 50, ) Woo, H. S., B. J. An, J. H. Bae, S. Kim, H. J. Choi, H. S. Han and C. Choi Effect of biologically active fractions from onion on physiological activity and lipid metabolism. J. Kor Soc. Food Sci. Nutr. 32, ) FIT Research Center and Mokpo National University International Symposium on the Utilization and Processing of Onions. p ) Chung, H. D Control of onion bulb rot during storage at low temperature by postharvest treatment of fungicides. J. Korean Soc. Hort. Sci. 23, ) Kim, H. K., H. C. Lee, M. H. Park and D. H. Shin Microflora of decayed onion bulbs and their suppression by fumigation treatment. Kor. J. Food Sci. Technol. 18, ) Lee, H. C., H. K. Kim, M. H. Park and D. H. Shin Confirmation of saprophytes of onions in Korea and effects of temperature, humidity and fumigation on Boyrtis-rot. Kor. J. Appl. Microbiol. Bioeng. 12, ) Da-Mota, V. M. and E. Palau Acoustic drying of onion. Drying Technol. 17, ) Kim, H. R., E. J. Seog, J. H. Lee and J. W. Rhim Physicochemical properties of onion powder as influenced by drying methods. J. Kor. Soc. Food Sci. Nutr. 36, ) Kang, N. S., J. H. Kim and J. K. Kim Modification of quality characteristics of onion powder by hot-air, vacuum and freeze drying methods. Kor. J. Food Preserv. 18, ) Kim, K. K Thermal characteristics of agriculture and fisheries by low temperature vacuum dryer. Proceedings of the KSME 1999 Spring Annual Meeting,
29 37) Kim, K. K., B. Y. Sung, H. S. Jung, S. Y. Choi and S. B. Moon A study on the thermal characteristics of the large low temperature vacuum dryer for biological drying. J. Kor. Soc. Marine Engineers. 24, ) AOAC International Official methods of anlysis of AOAC International 18th ed. AOAC International. 39) Vallls, F., M. T. Sancho, M. A. Ferrandez-Muino, S. Alonso-Torre and M. A. Checa High-pressure liquid chromatographic determination of ascorbic acid in cooked sausages. J. Food Prot. 65, ) Amerinem, M. A. and C. S. Ough Method for analysis of Musts and Win. Wiley & Sons. New York, USA. pp ) Lee, M. K. and H. Park Free amino acids of xylem-pith in panax ginseng root. Kor. J. Ginseng Sci. 11, ) Lee, K. S., H. P. Kwan, H. L. Sang, E. O. Choe and H. G. Lee The quality properties of dried carrots as affected by blanching and drying methods during storage. Kor. J. Food Sci. Technol. 35, ) Denizot, F. and R. Lang Rapid colorimetric assay for cell growth and survival modifications to the tetrazolium dye procedure giving improved sensitivity and reliablity. J. Immunol. Methods 89, ) LeBel, C. P., H. Ischiropoulos and S. C. Bondy Evaluation of the probe 2, 7-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol. 5, ) Kim, S. K. and M. K. Kim Effect of dried powders or ethanol extracts of onion flesh and peel on lipid metabolism, antioxidative and antithrombogenic capacities in 16-month-old rats. Kor. J. Nutr. 37, ) Park, J. and M. K. Kim Effects of onion flesh or peel feeding on antioxidantive capacity in 16-month-old rats high iron diet. Kor. J. Food Culture 20, ) Shon, M. Y., S. D. Choi, G. G. Kahng, S. H. Nam and N. J. Sung Antimutagenic, antioxidant and free radical scavenging activity of ethyl acetate extracts from white, yellow and red onions. Food Chem. Toxicol. 42, ) Dorant, E., P. A. van den Brandt and R. A. Goldbohm A prospective cohort study on Allium vegetable consumption, Netherlands. Cancer Res. 54, ) Sankaranrayanan, R., C. Varghese, S. W. Duffy, G. Padmakumary and N. E. Day. A case-control study of diet and lung cancer in Keraka, South India. Int. J. Cancer 75, ) Shon, M. Y. and S. K. Park Chemical components and nitrite scavenging activity of various solvent extracts from onions. Kor. J. Food Preserv. 13, ) Shahidi, F. and P. K. Wanasundara Phenolic antioxidants. Critical Rev. Food Sci. Nutr. 32, ) Jeong, C. H., J. H. Kim and K. H. Shim Chemical components of yellow and red onion. J. Kor. Soc. Food Sci. Nutr. 35, ) Kim, Y. H., M. Y. Shon and N. J. Sung Antioxidant and antimutagenic activities of hot water extract from white and yellow onions after simulated gastric digestion. J. Lif e Sci. 14, ),,, Proceedings of the Korean Nutrition Society Conference. Seoul. p ) Park, J., J. Kim and M. K. Kim Onion flesh and onion peel enhance antioxidant status in aged rats. J. Nutr. Sci. Vitaminol. 53,
제 출 문 경상북도 경산시 농업기술센터 귀하 본 보고서를 6차산업수익모델시범사업 농산물가공품개발 연구용역 과제의 최종보고서로 제출합니다. 2014 년 11 월 19 일 주관연구기관명 : 영남대학교 총괄연구책임자 : 한 기 동 연 구 원 : 김 상 욱 이 수 형 이 상
6차 산업 수익모델 시범사업 농산물가공품개발 연구용역 최 종 보 고 서 영남대학교 식품공학과 연구책임자 : 한 기 동 제 출 문 경상북도 경산시 농업기술센터 귀하 본 보고서를 6차산업수익모델시범사업 농산물가공품개발 연구용역 과제의 최종보고서로 제출합니다. 2014 년 11 월 19 일 주관연구기관명 : 영남대학교 총괄연구책임자 : 한 기 동 연 구 원 : 김
<C7D1BDC4BFAC20B1E8B5BFBCF6B9DABBE7B4D4676C75636F20C3D6C1BE5B315D2E687770>
Glucomannan 을이용한 기능성소재화연구 Study on the Functional and Processing Properties of Glucomannan for Food Material 연구기관 한국식품개발연구원 농림부 - 1 - - 2 - - 3 - - 4 - - 5 - - 6 - - 7 - - 8 - - 9 - - 10 - - 11 - - 12
hwp
최종연구보고서 - 1 - - 1 - - 2 - - 3 - - 4 - - 5 - - 6 - - 7 - - 8 - - 9 - - 10 - - 11 - - 12 - - 13 - - 14 - - 15 - - 16 - - 17 - - 18 - - 19 - - 20 - - 21 - - 22 - - 23 - - 24 - - 25 - - 26 - - 27 - - 28 -
Statistical Data of Dementia.
Screening of Prolyl Endopeptidase Inhibitors from Medicinal Plants. Lee Si-young, Lee Jung-han, Paik Young-Sook College of Environment and Applied Chemistry, Kyung Hee University. Statistical Data of Dementia.
γ
경락경혈학회지 Vol.27, No.1, pp.87 106, 2010 Journal of Meridian & Acupoint Dept. of 1 Meridian & Acupoint, 3 Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University 2 Division of Clinical
- 1 -
- 1 - - 2 - - 3 - - 4 - - 5 - - 6 - ι κ λ β β β β β - 7 - - 8 - - 9 - - 1 - - 11 - 마. - 12 - - 13 - - 14 - - 15 - - 16 - - 17 - - 18 - - 19 - - 2 - - 21 - - 22 - - 23 - - 24 - ι κ λ β β - 25 - - 26 - -
Journal of Life Science 2011, Vol. 21. No μ μ
Journal of Life Science 2011 Vol. 21. No. 8. 1120~1126 ISSN : 1225-9918 DOI : http://dx.doi.org/10.5352/jls.2011.21.8.1120 μ μ μ α β Journal of Life Science 2011, Vol. 21. No. 8 1121 μ μ 1122 생명과학회지 2011,
개최요강
55 2009. 5. ( ) ( ) < > 1. 1 2. 2. 2. 3 1) 3 2) 3 3) GC-MS 4. 5 1) 5 2) 5 3) ICP-OES 6 3. 7. 7 1) 7 2) 10. 13 1) 1g 13 2),,, 14 3), 15 4),, 15 4. 17 19 < > [ 1] 2 [ 2] ICP-OES 6 [ 3] 13 [ 4] 1g 13 [ 5]
전체 목차 1. 주류 일반 2. 기능성 3. 숙취 4. 주세법 5. 주류 일반 상식 6. 우리술 즐기기
국순당 배중호 대표의 우리 술 강좌 : 백세주 성공신화, 그 비결 전체 목차 1. 주류 일반 2. 기능성 3. 숙취 4. 주세법 5. 주류 일반 상식 6. 우리술 즐기기 1. 주류 일반 술 소비량으로 본 세계지도 집값으로 본 세계지도 군사비 지출로 본 세계지도 1. 주류 일반 주류일반 전통주 정의 전통주 특징 전통주 역사 국순당과 전통주 계승 전통주 담그기
한약재품질표준화연구사업단 단삼 ( 丹參 ) Salviae Miltiorrhizae Radix 생약연구과
한약재품질표준화연구사업단 단삼 ( 丹參 ) Salviae Miltiorrhizae Radix 생약연구과 - 1 - KP 11 CP 2015 Salvia miltiorrhizae Radix Salviae Miltiorrhizae Radix et Rhizoma Salvia miltiorrhiza Bunge Salvia miltiorrhiza Bunge salvianolic
1 1 10-0767050 2 10-1166045 3 10-0895586 4- - 10 4 10-1616887 11 5 10-1358259 12 6 10-0775080 7 10-0973839 8 10-1165269 15 9 10-1056952 16 10 10-1551559 11 10-1179175 12 10-1179177 19 13 10-1136822 20
DBPIA-NURIMEDIA
J. Ginseng Res. Vol. 30, No., 8-87 (006) y r w z yᜠÁÁ½Á *ÁÁ # w t gw tw (006 6 7, 006 6 0 ) Comparison of Phenolic Compounds Contents between White and Red ginseng and Their Inhibitory Effect on Melanin
untitled
理 葉 -- 猪 粒 葉 類 CNHN-93-01 行 93 年 01 01 93 年 12 31 瑩 林 理 參 行 理 94 年 2 28 1 理 葉 -- 猪 粒 葉 類 CNHN-93-01 行 93 年 01 01 93 年 12 31 瑩 理 林 理 理 E-mail: shihying@mail.chna.edu.tw (Morinda citrifolia) Rubiaceae Noni
untitled
3. 농업환경연구과 과제구분 기본연구 수행시기 전반기 연구과제 및 세부과제 수행 기간 소 속 책임자 농가에 적합한 부식성곤충 대량 사육기술 개발 12~ 13 농업환경연구과 곤충팀 이영혜 1) 부식성 곤충 먹이 제조 기술 개발 12~ 13 농업환경연구과 곤충팀 이영혜 색인용어 부식성곤충, 장수풍뎅이, 계통, 먹이제조 ABSTRACT In first check,
03 2012-076.hwp
Appl. Chem. Eng., Vol. 24, No. 1, February 2013, 18-23 Original article 각시가자미 껍질로부터 콜라겐 펩타이드 제조 및 이화학적 특성 장부식 이미진 정노희* 김태영** 씨엔에이바이오텍(주), *충북대학교 공업화학과, **충북도립대학 환경생명과학과 (2012년 9월 5일 접수, 2012년 11월 13일 심사,
항산화-2
67 DOI:10.3831/KPI.2008.11.3.067 A study on the comparison of antioxidant effects among wild ginseng, cultivated wild ginseng, and cultivated ginseng extracts Hae Young, Jang Hee Soo, Park Ki Rok, Kwon
한약재품질표준화연구사업단 금은화 ( 金銀花 ) Lonicerae Flos 생약연구과
한약재품질표준화연구사업단 금은화 ( 金銀花 ) Lonicerae Flos 생약연구과 - 2 - KP 11 Lonicerae Flos Lonicera japonica Thunberg - CP 2015 JP 16 Lonicerae Japonicae Flos Lonicerae Folium Cum Caulis Lonicera japonica Thunberg - Lonicera
한약재품질표준화연구사업단 강활 ( 羌活 ) Osterici seu Notopterygii Radix et Rhizoma 생약연구과
한약재품질표준화연구사업단 강활 ( 羌活 ) Osterici seu Notopterygii Radix et Rhizoma 생약연구과 - 2 - - 3 - KP 11 Osterici seu Notopterygii Radix et Rhizoma Ostericum koreanum Maximowicz, Notopterygium incisum Ting, Notopterygium
한수지 49(6), , 2016 Original Article Korean J Fish Aquat Sci 49(6), ,2016 제조방법을달리하여제조한껍질붙은냉동바지락 (Tapes philippinarum) 의껍질개패율및품질특성비교 박시영 강경훈
한수지 49(6), 743-749, 2016 Original Article Korean J Fish Aquat Sci 49(6),743-749,2016 제조방법을달리하여제조한껍질붙은냉동바지락 (Tapes philippinarum) 의껍질개패율및품질특성비교 박시영 강경훈 이재동 윤문주 강영미 1 성태종 2 권수현 3 추이권 4 김정균 * 경상대학교해양식품생명의학과
한수지 51(6), , 2018 Original Article Korean J Fish Aquat Sci 51(6), ,2018 토마토소스및토마토페이스트소스첨가구운굴 (Crassostrea gigas) 통조림의제조및품질특성 박준석 박두현 공청식
한수지 51(6), 647-655, 2018 Original Article Korean J Fish Aquat Sci 51(6),647-655,2018 토마토소스및토마토페이스트소스첨가구운굴 (Crassostrea gigas) 통조림의제조및품질특성 박준석 박두현 공청식 이영만 1 이재동 2 박진효 김정균 * 경상대학교해양식품생명의학과 / 해양산업연구소, 1 대일씨에프,
-, BSF BSF. - BSF BSF ( ),,. BSF -,,,. - BSF, BSF -, rrna, BSF.
1. 2010 6 1, 2 4 Ⅰ,Ⅱ 2013,, -,. - Human Cell.. -,., Biosand Filter(BSF) - BSF Main Filtering (Biofilm) BSF, BSF ( ),. -, BSF BSF. - BSF BSF ( ),,. BSF -,,,. - BSF,. -. -. -. - 2. BSF -, rrna, BSF. 2. -
Overview -ingredient - mechanism 2. Biomarker 3. In vitro study 4. In vivo study 5. Human study 6. 기능성 인정서 7.기준규격 인정서
*CJ standard Mw 40500 standard Mw 8000 CJ CJ Chitosan 1. 70g Sprague Dawley 1 2. Stainless steel cage 3. Ingredient Basal Control CJ Sucrose Starch Casein DL-methionine Corn oil Lard Choline bitartarate
한수지 49(6), , 2016 Original Article Korean J Fish Aquat Sci 49(6), ,2016 자연산과양식산동자개 (Pseudobagrus fulvidraco) 의시기에따른영양성분변화 임치원 김민아 계현진 윤나영
한수지 49(6), 779-784, 2016 Original Article Korean J Fish Aquat Sci 49(6),779-784,2016 자연산과양식산동자개 (Pseudobagrus fulvidraco) 의시기에따른영양성분변화 임치원 김민아 계현진 윤나영 송미영 1 심길보 * 국립수산과학원식품위생가공과, 1 국립수산과학원중앙내수면연구소 Seasonal
786 심길보ㆍ김민아ㆍ윤나영ㆍ송미영ㆍ정수정ㆍ임치원 (Ha and Kang, 990),.,,,,,,. 재료 재료및방법, , Table. 일반성분 AOAC (995), Kjeldahl, Soxhlet,. 지방산조성 Bligh and Dyer (959) 5 chl
한수지 49(6), 785-79, 206 Original Article Korean J Fish Aquat Sci 49(6),785-79,206 쏘가리 (Siniperca scherzeri) 의시기에따른영양성분변화 심길보 * 김민아 윤나영 송미영 정수정 임치원 국립수산과학원식품위생가공과, 국립수산과학원중앙내수면연구소 Seasonal Variation in the
untitled
理 葉 CNFH-88-04 行 87 年 9 1 88 年 6 30 類 葉 Staphylococcus aureus Staphylococcus epidermidis Streptococcus mutans Streptococcus sanguis Escherichia coli Klebsiella pneumoniae Pseudomonas aeruginosa Candida
033~50 ¿ŁÃ³¸® ¹×
ginsenoside 33 DOI : 10.3831/KPI.2010.13.2.033 ginsenoside Received : 10.05.24 Revised : 10.06.07 Accepted : 10.06.15 Key Words: ginsenoside, cultivated ginseng, mountain ginseng, red ginseng, fermentation
이 발명을 지원한 국가연구개발사업 과제고유번호 G1111700300320000000000000 부처명 한국환경산업기술원 연구사업명 토양지하수오염방지기술개발사업 연구과제명 시데로포아(Siderophore)의 대량생산을 통한 토양 및 지하수의 친환경 중금속 제거기술 개 발
(19) 대한민국특허청(KR) (12) 공개특허공보(A) (11) 공개번호 10-2013-0029213 (43) 공개일자 2013년03월22일 (51) 국제특허분류(Int. Cl.) C12N 1/15 (2006.01) C12P 21/00 (2006.01) C12R 1/77 (2006.01) (21) 출원번호 10-2011-0092470 (22) 출원일자 2011년09월14일
최은옥인하대학교식품영양학과 1. 1,200, %, 50%,, -linolenic acid. (linseed oil; 38%)..,, ( 1998),, (, 1998).,., -3/ -6,,,,. 433
최은옥인하대학교식품영양학과 1. 1,200, 2006 409... 40%, 50%,, -linolenic acid. (linseed oil; 38%)..,, ( 1998),, (, 1998).,., -3/ -6,,,,. 433 ,,.,, -3/ -6,,,,. 2. 2.1 들깨의발아 12 15 2cm (30) 12, 36, 48. 12, 40. 12, 36,
학술원논문집 ( 자연과학편 ) 제 50 집 2 호 (2011) 콩의식품적의의및생산수급과식용콩의자급향상 李弘䄷 * 李英豪 ** 李錫河 *** * Significance of Soybean as Food and Strategies for Self Suffici
학술원논문집 ( 자연과학편 ) 제 50 집 2 호 (2011) 97-137 콩의식품적의의및생산수급과식용콩의자급향상 李弘䄷 * 李英豪 ** 李錫河 *** * Significance of Soybean as Food and Strategies for Self Sufficiency Improvement Hong Suk Lee*, Yeong-Ho Lee**, and
한약재품질표준화연구사업단 고삼 ( 苦參 ) Sophorae Radix 생약연구과
한약재품질표준화연구사업단 고삼 ( 苦參 ) Sophorae Radix 생약연구과 - 1 - KP 11 Sophorae Radix Sophora flavescens Solander ex Aiton oxymatrine, matrine 1.0% CP 2015 Sophorae Flavescentis Radix Sophora flavescens Aiton - JP 16
이 발명을 지원한 국가연구개발사업 과제고유번호 KGM2420913 부처명 교육과학기술부 연구관리전문기관 연구사업명 전북분원운영사업 연구과제명 저탄소 녹생성장을 위한 바이오매스/에너지 개발 주관기관 한국생명공학연구원 연구기간 2009년 01월 01일 ~ 2009년 12월
(19) 대한민국특허청(KR) (12) 등록특허공보(B1) (45) 공고일자 2015년04월10일 (11) 등록번호 10-1509796 (24) 등록일자 2015년04월01일 (51) 국제특허분류(Int. Cl.) A61K 36/45 (2006.01) A23L 1/30 (2006.01) A61P 3/04 (2006.01) (21) 출원번호 10-2009-0108173
lastreprt(....).hwp
pheophytin Jukart.. 서론 재료및방법 . 650 nm (10). 3. 124 15 3 68 2 3 124 2, 3, 43 5, 5 23 (5). 4. 5 4 5 53. 650 nm (10),..,. 16 pheophytin Jukart.. IC 50 1mg/ml.. pheophytin Jukart.. IC 50 1mg/ml.
DBPIA-NURIMEDIA
Pollinator Visit, Characteristics of Secreted Nectar and Analysis of Nectar Sugar and Amino Acid Contents in Flower of Dendropanax morbifera Lev. Kim Moon-Sup, Kim Hyeusoo, Kim So-Dam 1, Park Sang-Jin
μ μ μ μ μ μ μ μ μ α μ μ β μ α μ α γ μ α β α α γ γ μ μ μ αα αα α α β μ α Diabetic Patients ( 천만 ) 35 30 25 20 15 10 5 0 1985 2003 2010 2025 Year Anual number of Diabetic Patients α β α α
보고서_pdf로.hwp
9:30-10:00 10:00-10:10 INTRODUCTION 10:10-11:40 ISSUES IN DIETARY ASSESSMENT IN COHORT STUDIES Alan Kristal (Fred Hutchinson Cancer Research Center, U.S.A.) Developing adiet questionnaire for alarge cohort
03-2ƯÁý -14š
Management on hazardous chemicals for production of safe produce Namjun Cho, Sumyeong Hong, Wonil Kim, Byungjun Park Chemical Safety Division, National Academy of Agricultural Science, RDA * Correspondence
한약재품질표준화연구사업단 작약 ( 芍藥 ) Paeoniae Radix 생약연구과
한약재품질표준화연구사업단 작약 ( 芍藥 ) Paeoniae Radix 생약연구과 - 2 - KP 11 CP 2015 JP 16 Paeoniae Radix Paeoniae Radix Alba Paeoniae Radix Rubra Paeoniae Radix Paeonia lactiflora Pallas paeoniflorin, albiflorin 2.3% Paeonia
Lehninger Principles of Biochemistry 5/e
David L. Nelson and Michael M. Cox LEHNINGER PRINCIPLES OF BIOCHEMISTRY Fifth Edition CHAPTER 18 Amino Acid Oxidation and the Production of Urea 2008 W. H. Freeman and Company Dietary proteins Synthesis
(....).hwp
sugar cane 계분 (%) a ATCC : American type Culture Collection, b IFO : Institute for fermentation, osaka, c MPNU : Mycological lab. Pusan National University d Mycelial
한수지 48(5), , 2015 Original Article Korean J Fish Aquat Sci 48(5), ,2015 Thermophilic bacillus 로제조한속성도루묵 (Arctoscopus japoncus) 액젓의이화학적특성
한수지 48(5), 674-680, 205 Original Article Korean J Fish Aquat Sci 48(5),674-680,205 Thermophilic bacillus 로제조한속성도루묵 (Arctoscopus japoncus) 액젓의이화학적특성 남기호 * 장미순 박희연 곽원주 국립수산과학원식품위생가공과 Physiochemical Characteristics
타피오카전분을이용한고효율배합사료개발 89.,, ph. (extruding) (steaming). (Lee et al., 203). (Yoon, 20). (Manihot esculenta Crantz),,,. amylose amylopectin (Chee, 986),.
한수지 47(6), 88-823, 204 Original Article Kor J Fish Aquat Sci 47(6),88-823,204 타피오카전분을이용한넙치 (Paralichthys olivaceus) 용고효율배합사료개발 김강웅 이진혁 배기민 김경덕 이봉주 한현섭 이경준 김성삼 * 국립수산과학원사료연구센터, 제주대학교해양생명과학과 Development
67-72
40 1, 025 029 (2013) Korean J. Poult. Sci. Vol.40, No.1, 025 029 (2013) http://dx.doi.org/10.5536/kjps.2013.40.1.025 25 Assessment of Antimicrobial and Antioxidant Effects of Ripened Medicinal Herb Extracts
- 1 -
11 1541000-001436-01 수출전략형신수요창출을위한홍마늘및바이오식품개발 (Development of red-garlic and its bio-food for create new market demand and develop of export items) - 1 - - 2 - - 3 - o o - 4 - o o - 5 - o α α - 6 - - 7
09-감마선(dh)
Journal of Radiation Industry 4 (3) : 253~257 (2010) Review Paper 감마선 조사가 포인세티아의 발근, 생육 및 색상변이에 미치는 영향 이은경* 김원희 김성태 강시용 1 국립원예특작과학원, 1 한국원자력연구원 Rooting, Growth, and Color Mutation of Poinsettias Affected
025~038-오공약침의
25 DOI : 10.3831/KPI.2008.11.4.025 A Study on Subchronic Toxicity Test and Method of Increasing Output of Scolopendrid Pharmacopuncture Kim Sung-chul *Dept. of Acupuncture & Moxibustion, Gwang-Ju Oriental
DBPIA-NURIMEDIA
J Korean Soc Food Sci Nutr 35(8), 961~966(2006) 한국식품영양과학회지 머루과피용매추출물의항산화성및아질산염소거작용 최선영 조현소 성낙주 경상대학교식품영양학과 농업생명과학연구원 The Antioxidative and Nitrite Scavenging Ability of Solvent from Wild Grape (Vitis Coignetiea)
ca_02.hwp
SPSPSPSP SPSPSPS SPSPSP SPSPS SPSP SPS 공기청정기 항균필터 SPS - KACA009-139 한국공기청정협회 2002년 12월 31일 제정 2016년 -월 -일 개정예정 http://www.kaca.or.kr 1.1 적용범위 이 표준은 에어필터로 공기중의 입자제거 및 미생물 제균 성능을 지닌 필터에 대하여
45권3호-최종본.indd
Kor J Fish Aquat Sci 45(3), 232-237 DOI : http: //dx.doi.org /0.5657/KFAS.202.0232 한수지 45(3), 232-237, 202 천연게향전구물질로서의홍게 (Chionoecetes japonicus) 자숙가수분해물의정미적특성 백정화. 정은정. 전선영. 차용준 * 창원대학교식품영양학과 Taste Components
12 (09-42-수정).hwp
J Korean Soc Food Sci Nutr 한국식품영양과학회지 44(3), 393~400(2015) http://dx.doi.org/10.3746/jkfn.2015.44.3.393 생맥산 농축액의 양을 달리하여 제조한 젤리의 품질 특성 및 항산화성 김현정 홍슬기 민아영 신숙경 심은경 윤준화 김미리 충남대학교 식품영양학과 Antioxidant Activities
103.fm
Lab. Anim. Res. 2010: 26(1), 15-20 Investigations of Samwhang-sasimtang Extracts on Biological Activities In Vitro and Vivo In-Chul Lee 1, Bae-Hwan Kim 2 * and Mee-Kyung Kim 1 * 1 Senior Industry Cluster
18 Journal of Agriculture & Life Science 49(2) root tissue. In addition, free amino acid and total polyphenolic compounds were analyzed in the leaf an
농업생명과학연구 49(2) pp.17-26 Journal of Agriculture & Life Science 49(2) pp.17-26 Print ISSN 1598-5504 Online ISSN 2383-8272 http://dx.doi.org/10.14397/jals.2015.49.2.17 Headspace GC-MS 법에의한삼채의휘발성화합물및아미노산성분분석
¾Æ¼¼·Î³ªº»¹®_Ãʱ³
The Secret Of ARONIA CONTENTS PART 01 Aronia melanocarpa 01 026 02 026 03 026 04 026 026 026 05 026 06 026 PART 02 01 90% 026 02 026 03 026 04 026 05 026 PART 03 01 026 02 026 PART 04 01 026 02 026 03
l l l l l l l l l Lee, Geon Kook None This project was designed to establish the Tumor Bank of National Cancer Center in 2000. From the first tumor sample in 2000, the total of tumor and tumor-related
최종보고서(한식연 김영언).hwp
보안과제 ( ), 일반과제 ( O ) 과제번호 107060-03 ( ) 농림수산식품부장관귀하 이보고서를 송이와부산물을이용한고부가가치가공제품개발 과제의보 고서로제출합니다. 2010 년 5 월 29 일 주관연구기관명 : 한국식품연구원 주관연구책임자 : 김영언 세부연구책임자 : 한대석 세부연구책임자 : 김인호 연 구 원 : 이창호 연 구 원 : 구경형 연 구 원
μ
μ 초콩의제조중기능적특성비교 173 Table 1. Changes in total polyphenol contents of Chokong as affected by soaking time Extracting solvents Chokong 1) Soaking time (days) 1 4 7 10 14 Water 70% ethanol solution 23.46±4.62
012임수진
Received : 2012. 11. 27 Reviewed : 2012. 12. 10 Accepted : 2012. 12. 12 A Clinical Study on Effect of Electro-acupuncture Treatment for Low Back Pain and Radicular Pain in Patients Diagnosed with Lumbar
Introduction 신뢰성 있는 결과 높은 품질의 제품을 생산하기 위해서는 제품의 공정 시스템이 중요 품질관리실험실은 품질보증과정에서 매우 중요한 역할 분석시스템은 품질관리실험실의 매우 중요한 요소 분석시스템의 결과를 기본으로 하여 제품의 품질을 결정 R&D 실험실
적정의 올바른 분석방법 Kopack Seminar May 2012 Agenda Introduction Risks and Measures Summary 1 1 Introduction 신뢰성 있는 결과 높은 품질의 제품을 생산하기 위해서는 제품의 공정 시스템이 중요 품질관리실험실은 품질보증과정에서 매우 중요한 역할 분석시스템은 품질관리실험실의 매우 중요한 요소
8(4) fm
Journal of Dental Hygiene Science Vol. 8, No. 4 pp. 367~373 (008) 황금 (Scutellaria baicalensis) 추출물에의한 Streptococcus mutans 의항균및부착억제효과 Á½ xá«x Á½ Á½ Áw w w w, 1 w e Effects of Antibacteria and Adhesive
03-서연옥.hwp
농업생명과학연구 49(4) pp.31-37 Journal of Agriculture & Life Science 49(4) pp.31-37 Print ISSN 1598-5504 Online ISSN 2383-8272 http://dx.doi.org/10.14397/jals.2015.49.4.31 국가산림자원조사 자료를 적용한 충남지역 사유림경영율 추정 서연옥
DBPIA-NURIMEDIA
KOREAN J. FOOD COOK. SCI. Vol. 31, No. 2, pp. 207~213 (2015) ISSN 2287-1780(Print) ISSN 2287-1772(Online) http://dx.doi.org/10.9724/kfcs.2015.31.2.207 구기자추출물함유음료의산화방지활성, 항당뇨효과, 유리아미노산과무기질함량 이경애 순천향대학교식품영양학과
YEONGGWANG BEOPSEONGPO SALTED YELLOW CORVINA Exquisite taste, Interweaving of Water Wind Sunshine Salt And time By human
MISuNG fishery association corporation delivers taste of time from endeavors to follow the traditional methods for three generations. We have the patented skill of making Gul-bi marinated with herb & lotus
특허청구의 범위 청구항 1 Na-알지네이트(Na-alginate), 합성 제올라이트(synthetic zeolite)와 분말활성탄(powdered activated carbon) 을 혼합하여 2 ~ 6 %의 CaCl 2 용액에서 경화시켜 만들어진 직경 1 ~ 5 mm의
(51) Int. Cl. (19) 대한민국특허청(KR) (12) 등록특허공보(B1) C02F 3/10 (2006.01) (21) 출원번호 10-2006-0053240 (22) 출원일자 2006년06월13일 심사청구일자 (56) 선행기술조사문헌 JP01207193 A KR1020030092674 A 2006년06월13일 (45) 공고일자 2007년10월29일
노인정신의학회보14-1호
제14권 1호 통권 제23호 www.kagp.or.kr 발행인 : 정인과 / 편집인 : 이동우 / 발행처 : 정인과 (152-703) 서울특별시 구로구 구로동 80번지 고려대학교 구로병원 정신과 / TEL : 02-818-6608 / FAX : 02-852-1937 발행일 : 2008년 4월 30일 / 제 작 : (주)엠엘커뮤니케이션 140-846 서울특별시
fm
J. Fd Hyg. Safety 20(1), 53 57 (2005) Ÿ w y, w s z w Á½ xá Á Á yá v w t œw Antioxidative, Antimutagenic and Cytotoxic Effects of the Mineral Water Seung-shi Ham, Soo-hyun Kim, Seon-young Moon, Mi-Sun Jeon,
jaeryomading review.pdf
4 5 6 7 8 9 10 11 12 13 1. S. Kim, H. Y. Jeong, S. K. Kim, S. Y. Choi and K. J. Lee, Nano Lett. 11, 5438 (2011). 2. E. Menard, K. J. Lee, D. Y. Khang, R. G. Nuzzo and J. A. Rogers, Appl. Phys. Lett. 84,
Sheu HM, et al., British J Dermatol 1997; 136: Kao JS, et al., J Invest Dermatol 2003; 120:
Sheu HM, et al., British J Dermatol 1997; 136:884-890 Kao JS, et al., J Invest Dermatol 03; 1:446-464 1 10 0 3 Day Normal MLE Lotion Lotion MLE Cream Cream 80 7 70 6 3 Day Normal MLE Lotion Lotion MLE
<C3D6C1BEBAB8B0EDBCAD2E687770>
Counter Pulse Generator TRX(Thyratron) Oscilloscope Pump Chamber Power Supply Oscilloscope Controller Inductor High Voltage Pulse Generator (-) 펄스폭:-0.5uS, 승압비:-1:2(GND) (-) 펄스폭:-2uS, 승압비:-1:1(GND)
e hwp
TITLE 'Dew Pressure Calculation for the Condenser Pressure' IN-UNITS ENG DEF-STREAMS CONVEN ALL DESCRIPTION " General Simulation with English Units : F, psi, lb/hr, lbmol/hr, Btu/hr, cuft/hr. Property
main.hwp
열화상 측정기를 이용한 안마의자의 인체 영향 평가 박세진, 구준모, 이현자 한국표준과학연구원 생활계측그룹 Evaluation of Massage Chair Effect on Human Body using Infrared Imaging/Radiometric Camera Se Jin Park, Jun Mo Koo, Hyun Ja Lee Human L ife Measurement
달생산이 초산모 분만시간에 미치는 영향 Ⅰ. 서 론 Ⅱ. 연구대상 및 방법 達 은 23) 의 丹 溪 에 최초로 기 재된 처방으로, 에 복용하면 한 다하여 난산의 예방과 및, 등에 널리 활용되어 왔다. 達 은 이 毒 하고 는 甘 苦 하여 氣, 氣 寬,, 結 의 효능이 있
대한한방부인과학회지 THE JOURNAL OF ORIENTAL OBSTETRICS & GYNECOLOGY VOL.17, NO.2 : 115-122 (2004) 달생산이 초산모 분만시간에 미치는 영향 * 북경한의원, ** 윤산부인과의원, *** 최은림산부인과의원, 상지대학교 한의과대학 부인과학교실 ****, 경희대학교 동서의학대학원 김성준 *****, 윤왕준
063~078 인삼
ginsenoside 63 DOI : 10.3831/KPI.2010.13.1.063 ginsenoside Received : 10. 01. 25 Accepted : 10. 02. 25 Key Words: ginsenoside, cultivated wild ginseng, wild ginseng, cultivated ginseng, HPLC Component
DBPIA-NURIMEDIA
한국소음진동공학회 2015추계학술대회논문집년 Study of Noise Pattern and Psycho-acoustics Characteristic of Household Refrigerator * * ** ** Kyung-Soo Kong, Dae-Sik Shin, Weui-Bong Jeong, Tae-Hoon Kim and Se-Jin Ahn Key Words
<B8F1C2F72E687770>
제1장 제17장 성홍열 및 사슬알균 감염증 사슬알균 (Streptococci)은 증식 중의 특징적으로 쌍 또는 사슬모양의 그람양성 알균 으로 catalase 음성, 통성혐기성균이며, 보통 한천배지에서는 발육이 어렵고 혈액이나 혈청 등을 첨가한 배지에서 잘 발육한다. 포도당이나 다른 탄수화물을 분해하나 포도당 을 분해하여 가스를 생성하지 않는다. 이들은 최소
untitled
Liver Plasma Dietary Cholesterol synthesis Bile FC CE CE CE LDLr CE CM-R VLDL CE CM FC Small Intestine Reverse Cholesterol Transport CE HDL CETP LDL CETP IDL FC CE LDLr Peripheral Tissue Fecal Sterol (cholesterol
박치영논문-1
HK-1000 55 DOI:10.3831/KPI.2008.11.3.055 HK-1000 A Study on the Effect of Herbal-acupuncture with HK-1000 Solution on Hyperlipidemia and Arteriosclerosis Induced Rats Park Chi-Young, Hong Kwon-Eui Dept.
(specifications) 3 ~ 10 (introduction) 11 (storage bin) 11 (legs) 11 (important operating requirements) 11 (location selection) 12 (storage bin) 12 (i
SERVICE MANUAL N200M / N300M / N500M ( : R22) e-mail : jhyun00@koreacom homepage : http://wwwicematiccokr (specifications) 3 ~ 10 (introduction) 11 (storage bin) 11 (legs) 11 (important operating requirements)
가자미식해의제조공정최적화 37., (Choi et al., 200).. 재료 재료및방법 (Verasper Jordan et Gilbert;, ), (, ), (, ) (, )., (, ), (, ), (, ), (, ), (, ), (, ). 가자미식해제조 (round
한수지 48(), 036-043, 205 Original Article Kor J Fish Aquat Sci 48(),036-043,205 반응표면분석법을이용한가자미 (Verasper moseri Jordan et Gilbert) 식해제조최적화 한대원 김덕기 한호준 조순영 2 * 강릉원주대학교식품과학과, 강릉원주대학교동해안해양생물자원연구센터, 2 강릉원주대학교식품가공유통학과
[ 화학 ] 과학고 R&E 결과보고서 나노입자의표면증강을이용한 태양전지의효율증가 연구기간 : ~ 연구책임자 : 김주래 ( 서울과학고물리화학과 ) 지도교사 : 참여학생 : 원승환 ( 서울과학고 2학년 ) 이윤재 ( 서울과학고 2학년 ) 임종
![[ 화학 ] 과학고 R&E 결과보고서 나노입자의표면증강을이용한 태양전지의효율증가 연구기간 : ~ 연구책임자 : 김주래 ( 서울과학고물리화학과 ) 지도교사 : 참여학생 : 원승환 ( 서울과학고 2학년 ) 이윤재 ( 서울과학고 2학년 ) 임종](/thumbs/103/161032648.jpg "[ 화학 ] 과학고 R&E 결과보고서 나노입자의표면증강을이용한 태양전지의효율증가 연구기간 : ~ 연구책임자 : 김주래 ( 서울과학고물리화학과 ) 지도교사 : 참여학생 : 원승환 ( 서울과학고 2학년 ) 이윤재 ( 서울과학고 2학년 ) 임종")
[ 화학 ] 과학고 R&E 결과보고서 나노입자의표면증강을이용한 태양전지의효율증가 연구기간 : 2013. 3 ~ 2013. 12 연구책임자 : 김주래 ( 서울과학고물리화학과 ) 지도교사 : 참여학생 : 원승환 ( 서울과학고 2학년 ) 이윤재 ( 서울과학고 2학년 ) 임종찬 ( 서울과학고 2학년 ) 소재원 ( 서울과학고 2학년 ) 1,.,.,.... surface
14.fm
Journal of the Korean Ceramic Society Vol. 44, No. 2, pp. 93~97, 2007. Preparation of High Purity Si Powder by SHS Chang Yun Shin, Hyun Hong Min, Ki Seok Yun, and Chang Whan Won Engineering Research Center
20121217--2012년AQM보고서_Capss2Smoke-자체.hwp
11-148523-1331-1 대기모델링 정보지원 시스템을 위한 표준자료 구축 연구(Ⅱ) - CAPSS2SMOKE 프로그램 개발 기후대기연구부 대기공학연구과 Ⅱ 212 목 차 i 목 차 ii 목 차 iii 목 차 iii Abstract v Ⅰ. 서 론.., (Kim et al, 28). Clean Air Policy Support System (CAPSS).
서론 34 2
34 2 Journal of the Korean Society of Health Information and Health Statistics Volume 34, Number 2, 2009, pp. 165 176 165 진은희 A Study on Health related Action Rates of Dietary Guidelines and Pattern of
유해중금속안정동위원소의 분석정밀 / 정확도향상연구 (I) 환경기반연구부환경측정분석센터,,,,,,,, 2012
11-1480523-001163-01 유해중금속안정동위원소의 분석정밀 / 정확도향상연구 (I) 환경기반연구부환경측정분석센터,,,,,,,, 2012 목 차 ⅰ ⅲ ⅳ Abstract ⅵ Ⅰ Ⅱ Ⅲ i 목 차 Ⅳ ii 목 차 iii 목 차 iv 목 차 v Abstract vi Abstract σ ε vii Abstract viii Ⅰ. 서론 Ⅰ. 1 Ⅰ. 서론.
No Slide Title
Antioxidant effect of Estrogen on Bovine aortic endothelial cells 가톨릭대학교의과대학서울성모병원산부인과김미란 Journal of Steroid Biochemistry and Molecular Biology 117 (2009) 74-80 Background Objectives Materials & Methods
0201_약물의효능-표지
National Institute of Food and Drug Safely Evaluation C O N T E N T S 005 007 049 059 063 067 069 National Institute of Food and Drug Safely Evaluation National Institute of Food and Drug Safely Evaluation
전립선암발생률추정과관련요인분석 : The Korean Cancer Prevention Study-II (KCPS-II)
전립선암발생률추정과관련요인분석 : The Korean Cancer Prevention Study-II (KCPS-II) 전립선암발생률추정과관련요인분석 : The Korean Cancer Prevention Study-II (KCPS-II) - i - - ii - - iii - - iv - - v - - vi - - vii - - viii - - ix - -
서강대학교 기초과학연구소대학중점연구소 심포지엄기초과학연구소
2012 년도기초과학연구소 대학중점연구소심포지엄 마이크로파센서를이용한 혈당측정연구 일시 : 2012 년 3 월 20 일 ( 화 ) 14:00~17:30 장소 : 서강대학교과학관 1010 호 주최 : 서강대학교기초과학연구소 Contents Program of Symposium 2 Non-invasive in vitro sensing of D-glucose in
목차 ⅰ ⅲ ⅳ Abstract v Ⅰ Ⅱ Ⅲ i
11-1480523-000748-01 배경지역 ( 백령도 ) 에서의 대기오염물질특성연구 (Ⅲ) 기후대기연구부대기환경연구과,,,,,,, Ⅲ 2010 목차 ⅰ ⅲ ⅳ Abstract v Ⅰ Ⅱ Ⅲ i 목차 Ⅳ ii 목차 iii 목차 iv 목차 μg m3 μg m3 v 목차 vi Ⅰ. 서론 Ⅰ μm μg m3 1 Ⅰ. 서론 μg m3 μg m3 μg m3 μm 2
<4D F736F F D20BAD3C0BAB1CDB0C5BACFC0C7C7D1BEE0C0E7B5EEC8B0BFEBB9E6BEC8BFA1B0FCC7D1BFACB1B8>
I. II. III. 1. 1) (1) ( ) [ ] Reeve's turtle [ ] Geoclemys(Chinemys) reevesii [ ] -, -kusa kame, - () [ ] [ ] 2025cm 30cm.,,.,...,.. [ ] [ ].. [ ] 68 1 46. [ ].,. [ ] a. 120130.,,.. (2) [ ] Trionyx sinensis
5
26 3 (2005 9 ) J Korean Oriental Med 2005;26(3):55-65 The Effcects of Psoraleae fructus Extract on Melanin Synthesis of B16 Melanoma Cells Jae-Ho Chung, Hyung-Sik Seo Dept. of Ophthamology, Otolaryngology
심장2.PDF
(Treatment of Hypertension with Associated Diseases) 1.. (140/90 mmhg). 80 mmhg. ( ). (atenolol ), (amlodipine ) 1. -1 nitrate. ACE diltiazem, verapamil. ACE. ( )., ACE diltiazem,, diltiazem, verapamil.
203044-3.hwp
(a) Xbal BamHll pbi101 Stsy(896bp) GUS(1800bp) Nos3 GTCGACTCTAGACTGAAA-----------ATGGCTGGATCCCCGGGTGGTCAGTCCCTTATGTTACGT XbaI BamHI GUS start codon 250 200 intensity 150 100 50 0 1 2 3 4 5 6 7 8 9 10
레이아웃 1
2012-2013 Research Models And Diet & Bedding Diet & Bedding Product Guide Diet & Bedding Product Guide 70 Orientbio Diet & Bedding (Rodent) No. 5L79 No. 5053 No. 5025 No. 5002C33 58Y1 DIO Rodent Purified
Pharmacotherapeutics Application of New Pathogenesis on the Drug Treatment of Diabetes Young Seol Kim, M.D. Department of Endocrinology Kyung Hee Univ
Application of New Pathogenesis on the Drug Treatment of Diabetes Young Seol Kim, M.D. Department of Endocrinology Kyung Hee University College of Medicine & Hospital E mail : ycell2@yahoo.co.kr Abstract
(......).hwp
7 6 4 10 20 30 ph 5 4 3 0 10 20 30 40 50 60 Fermentation time(day) Fig.2-1. Changes of ph in DLMK according to various fermentation temperature 2 4 10 20 30 Acidity (%) 1 0 0 10 20 30 40 50 60 Fermentation
DBPIA-NURIMEDIA
J East Asian Soc Diet Life 27(3): 348 363 (2017) http://dx.doi.org/10.17495/easdl.2017.6.27.3.348 348 1 1 2 1 1, 2 Mixed Culture Characteristics of Fungi Strains isolated from Korean Traditional Nuruk
386-390.hwp
386 HANYANG MEDICAL REVIEWS Vol. 29 No. 4, 2009 우리나라 미숙아의 통계와 의료비용 Statistics and Medical Cost of Preterm in Korea 윤혜선 을지대학교 노원을지병원 소아청소년과학교실 Hye Sun Yoon, M.D., Ph.D., Department of Pediatrics, Nowon
- 2 -
한약재품질표준화연구사업단 인동 ( 忍冬 ) Lonicerae Folium et Caulis 생약연구과 - 2 - KP 11 Lonicera japonica Thunberg 0.1% CP 2015 JP 16 Lonicera japonica Thunberg chlorogenic acid 0.10% Lonicera japonica Thunberg - β α - 3
저작자표시 - 비영리 - 변경금지 2.0 대한민국 이용자는아래의조건을따르는경우에한하여자유롭게 이저작물을복제, 배포, 전송, 전시, 공연및방송할수있습니다. 다음과같은조건을따라야합니다 : 저작자표시. 귀하는원저작자를표시하여야합니다. 비영리. 귀하는이저작물을영리목적으로이용할
저작자표시 - 비영리 - 변경금지 2.0 대한민국 이용자는아래의조건을따르는경우에한하여자유롭게 이저작물을복제, 배포, 전송, 전시, 공연및방송할수있습니다. 다음과같은조건을따라야합니다 : 저작자표시. 귀하는원저작자를표시하여야합니다. 비영리. 귀하는이저작물을영리목적으로이용할수없습니다. 변경금지. 귀하는이저작물을개작, 변형또는가공할수없습니다. 귀하는, 이저작물의재이용이나배포의경우,
DBPIA-NURIMEDIA
Comparison of Total Flavonoids and Phenolic Contents of Propolis Collected in Korea Woo, Soon Ok*, In-Pyo Hong and Sangmi Han Sericultural & Apicultural Materials Division, Department of Agricultural Biology,
歯 PDF
* * The Effects of Oocyte Oocytes Intracytoplasmic ICSI) Kee TaekHoo Hai * SikChun Department of Obstetrics and Gynecology, School of Medicine, Kyungpook Taegu, *Department of Animal Science, Taegu Kyungbuk,