접수번호 발표번호 제 25 차춘계학술대회포스터전시리스트 제목책임저자발표자소속 Islet biology & insulin secretion, immunology & tracsplantation KDA-S P7 Captopril prevents oxidati

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1 접수번호 발표번호 제 25 차춘계학술대회포스터전시리스트 제목책임저자발표자소속 Islet biology & insulin secretion, immunology & tracsplantation 002 P7 Captopril prevents oxidative stress-induced apoptosis and insulin suppression in pancreatic β-cells 진현정고관표제주대학교병원 1, 한국병원 P8 Successful endoscopic ultrasound-guided ethanol ablation of multiple insulinomas accompanied with multiple endocrine neoplasia type 1 (MEN1) 이우제이민정서울아산병원 P9 T3 improves pancreatic β cell-line proliferation 박정현한나인제대학교부산백병원내분비센터 1, 백인제기념임상의학연구소분자치료연구실 2 P10 Co-culture with α TC-6 cells and β TC-1 cells: morphology and function 박정현정혜숙인제대학교백인제임상의학연구소분자치료연구부 1, 인제대학교의과대학내분비대사내과 2 P11 Sunitinib 투여후인슐린종으로전환된신경내분비종양 1 례정혜승온정헌서울대학교의과대학내과학교실 1 P12 스테로이드치료없이저절로호전을보인약제유발인슐린자가면역증후군 1 예박정현김영구인제대학교부산백병원내분비대사내과 1 P13 P14 RV-1 from Rhus verniciflua protects pancreatic beta cells against high glucose and palmitate-induced glucolipotoxicity through its antiapoptotic action and activating IRS2 signaling Soy leaf regulates glucose-insulin system in diabetic mice and pancreatic beta cells 김윤철 이동성 원광대학교한방체액조절연구센터 1, 원광대학교약학대학천연물신약표준화소재은행 2, 원광대학교약학대 학 3 정태숙이화한국생명공학연구원 1, 한국과학기술연합대학원 2, 충남대학교 3 P15 Enhanced gene transfer to pancreatic islets using glucagon-like peptide (GLP)-1 임성희 채희영한림대학교성심병원내과 1, 연세대학교세브란스병원 내과 2, 한림대학교일송연구소 3 P16 Anti-hypoxia effect of perfluorocarbon carried alginate microcapsule 윤건호박헌석가톨릭대학교성의교정내분비내과연구실 1 Insulin action & obesity 026 P23 GLP-1 Levels are Markedly Increased 1 Month after Laparoscopic Mini-Gastric Bypass Surgery in Non-obese Patients with Type 2 Diabetes 박형규염석천순천향대학교서울병원 P24 비비만형제2형당뇨병동물모델에서스트레스부하에따른혈당의변화및 Metformin과 Exenatide의효과 조재형양혜경가톨릭대학교내분비내과학교실 1

2 P25 P26 P27 Long-term central infusion of adiponectin improves energy and glucose homeostasis by decreasing fat storage and suppressing hepatic Poor Compensatory Insulin Secretion against Insulin Resistance during Oral Glucose Tolerance Tests in Korean Subjects with Impaired Glucose Tolerance or Association of obstructive sleep apnea and glucose metabolism in nonobese Koreans 강선아박선민호서대학교식품영양학과 1 조영민 김영기 Seoul National University College of Medicine1, Eulji University College of Medicine 2 김난희 서지아고려대학교의과대학내분비내과 1, 고려대학교의과 대학호흡기내과 2 P28 건강한한국인성인에서관상동맥칼슘지수와비알코올성지방간의연관성이은정서미혜성균관의대강북삼성병원내분비내과 1 P29 Degrees of negative influence of BMI on the ratio of glycated albumin to 이병완김광준연세대학교의과대학내과학교실 1, 연세대학교세브 glycated hemoglobin are dependent on compensatory secretory function over 란스병원 2 P30 AMPK 과발현에의한미토콘드리아에너지대사관련유전자의변화 이혜정 박미경동아대학교의과대학약리학교실 1, 동아대학교의과 대학내과학교실 2, 미토콘드리아허브제어센터 3 P31 Endurance training increases serum uncarboxylated osteocalcin level and decreases HOMA-IR via reduction of serum leptin in obese young patients 안철우 김민경 연세대학교의과대학강남세브란스병원내분비내과 1 P32 Momordica charantia attenuates high-fat diet-induced glucose tolerance and 박철영최정묵강북삼성병원당뇨병연구소 1, 성균관대학교의과대학 inflammation. 강북삼성병원 2 Anti-diabetic and anti-adipogenic effects of a novel selective 11βhydroxysteroid P33 dehydrogenase type 1 inhibitor, KR-67183, in the diet-induced 김기영 박지선 한국화학연구원 1, 충남대학교신약전문대학원 2 obese mice P34 당뇨병전기한국인에서피니톨이경구당부하검사로산출한인슐린분비에미치는영향 박강서 김동필 을지대학병원 1 P35 The improvement insulin resistance of Type 2 diabetes after liver transplantation. 조호찬 김상진 계명대학교동산병원내분비내과 1 P36 Structural and functional cardiac abnormalities in sarcopenic obesity 박주리박주리한림대학교의료원 1, 고려대학교안산병원 2 Clinical diabetes & therapeutics P43 Clinical Usefulness of a Magnifier for Insulin Pens 조영민 이주희충남대학교의과대학내과학교실 1, 서울대학교의과 대학내과학교실 2 P44 인지기능장애가초래된인슐린종 1예 이진우 이진우이진우내과 1, 울산의대울산대학교병원내과 2, 외과 3, 진단병리과 4 P45 말단비대증에대한수술적치료후발생한제1형당뇨병 1예 강은석 김원진연세대학교의과대학내과학교실 1, 연세대학교의과 대학내분비연구소 2, 세브란스병원당뇨병센터 3 P46 우리나라제2형당뇨병환자의투약준수에따른임상적, 경제적결과 : 3년간추적이관우이민석아주대학교의과대학내분비대사내과학교실 1, 아주대연구학교의과대학예방의학교실 2, 아주대학교병원간호 P47 제2형당뇨병환자에서대체의학사용의변화 이관우 이민석아주대학교의과대학내분비대사내과학교실 1, 아주대 학교병원영양팀 2, 경희대학교내분비대사내과 3, 한

3 P48 Experience of premixed insulin lispro 50/50 이병완송선옥연세의대 1 P49 P50 P51 P52 P53 P54 P55 P56 Therapeutic effects of NecroX compound on nonalcoholic steatohepatitis by suppressing mitochondrial reactive oxygen species The Prevalence and degree of control of hypertriglyceridemia in patients with type 2 diabetes in statin era Spurious Elevation of Glucose Levels during administration of high dose of vitamin C in a Patient with Type 2 Diabetes on Hemodialysis Lipid-lowering and anti-inflammatory effects of individualizing starting doses of atorvastain according to baseline LDL-cholesterol levels in patients with type 2 Treatment of autoimmune diabetes by TLR2 tolerance in conjunction with DPP4 inhibition Optimal candidates for sitagliptin switching from sulfonylurea to reduce hypoglycemia in type 2 diabetic patients Efficacy and safety of dipeptidyl peptidase-4 inhibitors added to ongoing metformin and sulfonylurea therapy in patients with type 2 diabetes in Korea Serum 25-hydroxyvitamin D insufficiency is associated with poor glycemic control in Korean adults with diabetes: Analysis of the Korea National Health 송민호 정효균충남대학교병원특성화연구센터 1, 충남의대생화학교 실 2, 생명공학연구원동물모델센터 3, LG생명 4 김미경이은주인제의대 1 함종렬김수경경상대학교병원내분비내과 1 김성래 손장원가톨릭대학교부천성모병원 1, 인제대학교일산백병원 2, 한양대학교구리병원 3, 경희대학교병원 4, 건국대학 이명식김도훈삼성서울병원, 성균관의과대학 1 차봉수 김현민연세대학교의과대학내과학교실 1, 연세대학교의과 대학의과학과 2, 연세대학교세브란스병원내분비내 최성희김예안서울대학교의과대학내과학교실 1 P57 심한저혈당환자의임상적특징의분석강미연범재원성가롤로병원 1 안지현이석홍중앙대학교병원내분비내과 1, 중앙대학교병원영양과 2 P58 한국인당뇨병의분류및임상및생화학적특성 허갑범 임정수연세의대내분비내과 1, 허내과 /21세기당뇨병혈관 연구소 2 P59 골다공증성피로골절을동반한 LADA 환자 1 례전숙박소영경희의대 1 P60 P61 P62 P63 Safety and efficacy of saxagliptin in combination with submaximal sulfonylurea versus uptitration of sulfonylurea in Korean patients with type 2 diabetes 새롭게진단받은제2형당뇨병환자에서미세단백뇨유무에따른상완-발목맥파속도와나트륨섭취와의관계 The effect on endoplasmic reticular stress in the liver and pancreas of prediabetes and diabetes stage OLETF rats Effect of Atractylodis Rhizoma Alba water extract on streptozotocin-induced diabetes in rats. 안철우하지윤연세대학교의과대학강남세브란스병원내분비내과 1 민경완안희정을지병원영양과 1, 을지대학교의과대학내과학교실 2 유순집이성수가톨릭의대내분비학교실 1 한윤경 한윤경동국대학교한방신약개발센터 1, 동국대학교한의과대 학본초학교실 2 P64 당뇨병성케톤산증으로발현되고복강내농양이합병된췌장암 1 예박태선김웅지전주병원 1, 전북대학교병원내분비대사내과 2 P65 The well-being and treatment satisfaction of diabetic patients in general hospital in Korea 박이병박이병가천대길병원내분비대사내과 1

4 Relation of Absolute or Relative Adiposity to Insulin Resistance, Retinol Binding P Protein-4, Leptin and Adiponectin in Type 2 Diabetes 한경아 김유림 을지대학교내분비내과 P67 Evaluation of SD CodeFree Glucose Monitoring System 배학연 신지혜 조선대학교병원내분비대사내과 1 Relative glucagon excess would precede the development of diabetes in P patients with low insulin resistance and low insulin secretion reserve. 이문규 신상만 삼성서울병원내분비-대사내과 1 Associations of plasma homocysteine and albuminuria with arterial stiffness in P Korean patients with type 2 diabetes 박중열 황윤우 울산의대서울아산병원 1 The relation of serum neutrophil elastase concentration and serum elastase P70 박요한최영식고신대학교복음병원 1, 고신대학교의과대학 2, 아주대 129 activity in metabolic syndrome 학교병원 3 Hyperinsulinemic Hypoglycemia Associated with Focal Pancreatic Fat P Replacement of Unknown Etiology : A case report 최영식 권수경 고신대학교복음병원내과학교실 1 The Effect of Aerobic and Resistance Exercise on Cardiac and Mitochondrial National Research Laboratory for Mitochondrial P72 한진고태희 133 Function in Diabetic Rats Signaling, Department of Physiology, Cardiovascular Prevalence and clinical characteristics of latent autoimmune diabetes in P adults(lada) aged years in NHIC, Ilsan Hospital 남주영 남주영 국민건강보험일산병원내과 1, 김포우리병원내과 2 P74 제 2형당뇨병을동반한한국인중년남성에서남성호르몬결핍조용욱김경수 CHA의과학대학교분당차병원내과 1, CHA의과학대학 139 교분당차병원가정의학과 2, CHA의과학대학교강남 Complementary role of rapid current perception threshold test adding to Department of Inetrnal Medicine, Sanggye Paik P75 고경수김정민 142 Michigan Neuropathy Screening Instrument in the diagnosis of diabetic Hospital, Cardiovascular and Metabolic Disease 148 P76 A Case of Recurrent Hyperglycemia-Induced Hemichorea-Hemiballism 김재택 김미이 중앙대학교병원내분비내과 1 제2형당뇨병환자에서경동맥프라그에의한협착정도와경동맥내막중막두께와 P 의관련성 문성대 모은영 가톨릭대학교의과대학내과학교실내분비대사내과 P78 A case of pentamidine induced hypoglycemia 송기호 송기호 건국대학교병원내과 P79 Factors associated with peripheral nerve conduction in type 2 diabetic patients 정민영 정진욱 전남의대내과학교실 P80 유산산증없이발생한메포르민에의한급성신손상 1예 안유헌 박정환 한양대학교의과대학내과학교실 1 Serum vitamin D status and its relationship with glucose parameters in patients P with type 2 diabetes mellitus 강호철 김희경 전남대학교의과대학내과학교실 P82 Comparisons of vildagliptin-metformin vs, glimepiride-metformin vs. sitagliptinmetformin treatments in type 2 diabetes 오태근전현정충북대학교의과대학내과학교실 1 P83 노인당뇨병환자에서노인증후군의관리유형준한정완한림대학교한강성심병원내분비내과 1

5 Epidemiology & genetics P90 P91 Depression and suicidal ideation among adults with diabetes mellitus: the 4th Korea National Health and Nutrition Examination Survey ( ) Increased Serum Bone Morphogenic Protein 4 (BMP-4) Levels in Newly Diagnosed Type 2 Diabetes Mellitus 김대중한승진아주대학교내분비대사내과학교실 1 권혁상전현지가톨릭대학교의과대학내분비내과 P92 일종합병원근로자의생활습관요인이대사증후군유병위험에미치는영향최금희최금희부산성모병원 1 P93 P94 Association of hepatokines and nonalcoholic fatty liver disease according to body mass index Serum adipocyte fatty acid-binding Protein levels are associated with sarcopenia in Korean adults, regardless of visceral obesity 김난희은채령고려대학교의과대학내분비내과 1, 고려대학교의과대학호흡기내과 2 인제대학교의과대학내분비대사내과및인제대학교원종철김태년심혈관및대사질환센터 1, 인제대학교의과대학내분 P95 MIG6 gene polymorphism in diabetic patients 구본정이인석가톨릭대학교대전성모병원내분비내과 1, 충남대학교병원내분비내과 2, 대전을지대학병원내분비내과 3 P96 P97 신장이식후새롭게발생하는당뇨병에서성별에따른췌장아연수송체유전자변이의영향 Vitamin D is inversely associated with diabetes in middle-aged and elderly in Chuncheon: Hallym Aging Study 강은석최은영연세대학교의과대학내과학교실 1 최문기류옥현한림대학교내과학교실 1, 강릉시보건소 2 P98 Aspirin Resistance Epidemiology study in Korean Type 2 Diabetic Patients 박철영김종대성균관의대강북삼성병원내분비내과 1, 가천의대길병원내분비내과 2, 가톨릭의대서울성모병원내분비 P99 Trends in the prevalence of metabolic syndrome among the population with Dept of Preventive Medicine, The Catholic University 박용문고승현 diabetes and pre-diabetes in Korea: Korean National Health and of Korea 1, Dept of Internal Medicine, The Catholic P100 i i i i S S Relation between serum ferritin levels and metabolic risk factors in Korean Department of Internal Medicine, The Catholic 박용문안유배 adolescents University of Korea 1, Department of Preventive P101 P102 당뇨병이없는한국인에서정상범위에서의공복혈당증가에따른대사증후군의빈도 Association of the DDAH2 gene polymorphism with type 2 diabetes and hypertension 이재민문현진을지대학병원내분비대사내과 1, 을지대학교생화학교실 2 박근규서현애경북대학교 1, 동국대학교 2 P103 국민건강영양조사를이용한대사증후군과우울증상강준구김소라한림대학교성심병원 1, 한림대학교한강성심병원 2, 한림대학교춘천성심병원 3, 한림대학교강남성심병원 4, P104 Incidence of diabetes mellitus in a Korean rural population and its related risk factors: the Chungju Metabolic disease Cohort (CMC) Study. 윤건호신정아가톨릭대학교의과대학내분비 - 대사내과 1, 가톨릭대학교의과대학예방의학교실 2, 가톨릭 U- 헬스케어사

6 069 P105 Serum 1,5-anhydroglucitol is not associated with metabolic syndrome in well or moderately controlled type 2 diabetes 박철영김원준울산대학교의과대학강릉아산병원내분비내과 1, 성균관대학교의과대학강북삼성병원내분비내과 P106 Sarcopenia is independently associated with cardiovascular diseases in Korean adults: the Korea National Health and Nutrition Examination Survey (KNHANES) in 2009 황유철 진상욱 Department of Endocrinology and Metabolism Kyung Hee University School of Medicine 1, Kyung Hee University Hospital at Gangdong P107 Effect of Calpain-10 and Adiponectin gene polymorphism on insulin secretion and insulin resistance of type 2 diabetes mellitus 안철우이영미연세대학교의과대학강남세브란스병원내분비내과 P108 Gender differences in the association between muscle mass and metabolic diseases among Korean young adults : the Korean National Health and Nutrition Examination Survey (KNHANES) 박용문김병철가톨릭대학교의학전문대학원 1, 가톨릭대학교예방의학교실 2, 가톨릭대학교내과학교실내분비내과 P109 The relationship between sarcopenia and hypertension in the Korean elderly 박용문박유미가톨릭대학교의과대학 / 의학전문대학원 1, 가톨릭대학교예방의학교실 2, 가톨릭대학교내과학교실 / 내분비 P110 P111 Association between vitamin D levels and Metabolic Risk Factors among Korean Adolescents Association between Plasma Manganese level and Diabetes Mellitus in Korean Adults 박용문이승원가톨릭대학교의과대학 / 의학전문대학원 1, 가톨릭대학교의과대학 / 의학전문대학원예방의학교실 2, 가톨릭 School of Medicine, The Catholic University of Korea, 박용문박경민 Seoul, Korea 1, Department of Preventive Medicine, 141 P112 The ENPP1 K121Q Polymorphism Influence Effect of Web-based Lifestyle Intervention on Insulin Resistance 최태인강지연한국수력원자력방사선보건연구원방사선의학연구팀 P113 Assocication of Clusterin Gene Polymorphisms with Type 2 Diabetes and Metabolic Syndrome 전언주전언주대구가톨릭대학교병원내과학교실 1, 경북대학교병원내과학교실 P114 Association of Monocyte Chemoattract protein-1 (MCP-1) polymorphism and microcomplications of type 2 diabetes 오태근전현정충북대학교의과대학내과학교실 1 Acute & chronic complication 005 P121 Association between serum ceruloplasmin levels and arterial stiffness in Korean men with type 2 diabetes mellitus 박중열이민정서울아산병원 P122 Case of Streptococcus Pneumonia Infection after Acupuncture and Moxibustion in a Diabetic Patient 구본정김태균충남대학교병원 P123 P124 Taurine ameliorates the progression of diabetic nephropathy in type2 diabetic rat model. Association of Mean Platelet Volume with Fasting Plasma Glucose Level according to Glucose Tolerance Status 정춘희 이은수연세대학교원주의과대학내분비내과 1, 삼성서울병 원건강의학센터내분비내과 2, 순천향대학교의과대 김상용강지인조선대학교병원내분비대사내과 1

7 Serum Cystatin C is not Associated with Arterial Stiffness in Type 2 Diabetes P Patients with Normal Renal Function 박형규 박형규 순천향대학교서울병원 1 The prevalences of diabetic retinopathy and nephropathy are lower in type 2 P diabetic patients with non-alcoholic fatty liver disease 김철희 김보연 순천향대학교부천병원내분비대사내과 P127 Urinary adiponectin concentration is associated with microalbuminuria 박철영 전원선 강북삼성병원 1 Implication of Circulating Omentin-1 Level on the Arterial Stiffness and Carotid P Plaque in Type 2 Diabetes 백세현 류혜진 고려대학교의과대학, 내분비대사내과 1 Associations of Fetuin-A levels with insulin resistance and vascular complications P129 목지오 067 in type 2 diabetic patients 정찬희 순천향대학교부천병원내분비내과 1 P130 Apoptosis of osteoblastic MC3T3-E1 cells in lipotoxicity or glucolipotoxicity 김승만김승만백인제기념임상의학연구소분자치료연구실 1, 인제대 077 학교부산백병원당뇨병센터 2 P131 A case of recurrent of diabetic muscle infarction 진흥용유혜민 Chonbuk National University Hospital 1, Eulji 078 Uiniversity Hospital P132 당뇨병신경병증에서전류감각신경역치검사의유용성 구보경 온정헌 서울대학교의과대학, 서울특별시보라매병원 1 Retinoic Acid increases nerve growth factor and prevents neuropathy in OLETF P rats 안철우 권은진 연세대학교의과대학강남세브란스병원내분비내과 1 Clinical study for diagnostic efficacy of diabetic angiopathy using P134 안철우김지운연세대학교내분비내과 1, 고려대학교기계공학부 2, 094 hemorheological measurement system (RheoScan) 연세대학교심장내과 P135 고혈당성고삼투압상태환자에서동반된스트레스성심근병증 1예 김인주 김원진 부산대학교병원내분비내과 1 The Role of Orphan Nuclear Receptor Estrogen-related receptor γ (ERRγ) during Department of Biochemistry and Cell Biology P136 이인규김지현 109 Vascular Calcification process. Kyungpook National University School of Medicine 1, 118 P137 Antiproliferative effect of rutin on atherosclerosis in vascular smooth muscle cell 유성훈 강동현 한강성심병원내분비내과 P138 제 2형당뇨병환자에서대상포진발병과관련된인자 장상아 이정민 가톨릭대학교의과대학내과학교실 1 P139 단백뇨를동반한당뇨병환자와인지기능저하간의연관성박용수홍상모한양대학교내분비내과 1, 한양대학교신경과 2, 한양 160 대학교핵의학과 3 Association of glycated albumin with diabetic peripheral neuropathy and Division of Endocrinology, Department of Internal P140 문성대김은숙 162 albuminuria in Type 2 diabetes Mellitus Patients Medicine, Incheon St. Mary\'s Hospital, the Catholic 163 P141 The Vascular Protective Effect of GLP-1 on HMVEC in Hyperglycemic conditions 김병준 임동미 건양의대내분비대사내과 1, 순천향의대, 의학연구소 P142 장기간혼수상태에서회복된저혈당성뇌병증 1예 김기회 김기회 예수병원 1

8 Behavioral medicine & education 001 P149 제2형당뇨병환자외래진료중의사-환자의사소통방법에대한비교연구 : 원터치혈당관리소프트웨어 (OTDMS) vs. 환자일지 고경수김금옥인제대학교상계백병원내과, 심혈관대사질환센터 P150 Effects of Diabetic Camp in Type 2 Diabetic Patients 구본정김태균충남대학교병원 1 P151 The factors which influence the degree of satisfaction in OPD diabetic patients 박정현손주연인제의대부산백병원내분비대사내과당뇨병센터 1 P152 당뇨특이적삶의질에영향을미치는요소이관우이민석아주대학교의과대학내분비대사내과학교실 1, 아주대학교의과대학예방의학교실 2, 아주대학교병원영양 P153 당뇨병환자들의심화교육후지식및생활습관의변화안선희안선희강북삼성병원당뇨병전문센터 1, 강북삼성병원내분비내과 2 P154 당뇨집단영양교육비교분석정소희정소희부산대학교병원영양팀 1, 부산대학교병원내분비대사내과 2 P155 환자중심당뇨병영양교육프로그램개발을위한사전요구도조사이혜옥이혜옥강동경희대학교병원영양팀 1, 내분비대사내과 2 P156 가속도계를이용한운동교육방법의차이가전당뇨병환자들의관리지표에미치는영향 문여진문여진강북삼성병원당뇨센터운동처방실 1, 성균관의대강북삼성병원내분비내과 2 P157 인터넷기반으로한당뇨관리프로그램적용후당화혈색소의개선효과최미주최미주강북삼성병원당뇨전문센터 1, 강북삼성병원내분비내과 2 P158 제2형당뇨병환자에서식생활및생활습관지침의순응도평가와혈당조절관련성분석 P159 Evaluation of nutrition diagnosis implemented for T2DM out-patients 최진선최진선 송윤주임정현서울대학교병원급식영양과 1, 서울대학교식품영양학과 2, 가톨릭대학교식품영양학과 3 Diabetes Mellitus Center, Kangbuk Samsung Hospital 1, Department of Dietetic, Kangbuk P160 노인당뇨병환자에서혈당조절의관련인자김동림김동림건국대학교병원 1, 내분비대사내과 2, 외래간호팀 3 P161 The characteristics of T2DM patient related group nutrition education 김희영김희영 Diabetes Mellitus Center, Kangbuk Samsung Hospital 1, Department of Dietetic, Kangbuk P162 아동의신체활동인자와뇌신경세포생성인자의관계김현준김현준경남대학교체육교육과 1

May 10~ Hotel Inter-Burgo Exco, Daegu Plenary lectures From metabolic syndrome to diabetes Meta-inflammation responsible for the progression fr

May 10~ Hotel Inter-Burgo Exco, Daegu Plenary lectures From metabolic syndrome to diabetes Meta-inflammation responsible for the progression fr May 10~12 2012 Hotel Inter-Burgo Exco, Daegu Plenary lectures From metabolic syndrome to diabetes Meta-inflammation responsible for the progression from obesity to metabolic syndrome originates in the