Original Articles Korean Circulation J 2002;3212:1072-1077 Tc-99m MIBI 심근관류스펙트를이용한좌심실질량의측정 : 심초음파를이용한측정법과의비교 배선근 1 안병철 1 이상우 1 정신영 1 양동헌 2 박헌식 2 조용근 2 이재태 1 채성철 2 전재은 2 박의현 2 이규보 1 Left Ventricular Mass Measurement Using Tc-99m MIBI Myocardial Perfusion SPECTComparison with Echocardiographic Method Sun Keun Bae, MD 1, Byeong-Cheol Ahn, MD 1, Sang Woo Lee, MD 1, Shin Young Jeong, MD 1, Dong Heon Yang, MD 2, Hun Sik Park, MD 2, Yong Geun Jo, MD 2, Jaetae Lee, MD 1, Shung Chull Chae, MD 2, Jae Eun Jun, MD 2, Wee Hyun Park, MD 2 and Kyu Bo Lee, MD 1 1 Department of Nuclear Medicine, 2 Internal Medicine, Kyungpook National University Hospital, Kyungpook National Unversity Medical School, Daegu, Korea ABSTRACT Background and ObjectivesA left ventricular mass LVM can be used as a prognostic factor in patients with cardiovascular disease, and echocardiographic LVM measurements are most commonly used. We have measured LVM using quantitativel gated myocardial perfusion SPECT QGS, and compared these results with LVM measured by echocardiography. Subjects and MethodsOne hundred and sixteen subjects M/F66/50, mean age58 yrs underwent both rest QGS with Tc-99m MIBI and echocardiography. On visual interpretation, thirty-six subjects 31% showed perfusion defects. The myocardial volume was obtained using the AutoQU- ANT program, and the LVM LVMSPECT was calculated by multiplying the volume by the specific gravity of the myocardium. We also measured the echocardiographic LVM LVMEcho by the Devereux formula, within one month of the LVMSPECT. ResultsThe LVMSPECT and LVMEcho were well correlated r 0.717, p0.001, but a significant difference was noted between the two values. The mean difference between the LVMSPECT and LVMEcho was 24 g. The LVMEcho was smaller than the LVMSPECT in those subjects with a small LVMEcho, and greater than the LVMSPECT in the subjects with a large LVMEcho. The difference between the LVMEcho and LVMSPECT LVMEcho-LVMSPECT was positively correlated with the LVMEcho r0.893, p0.001. ConclusionThe LVMs measured by gated myocardial perfusion SPECT and echocardiography were well correlated. But they were significantly different, especially in subjects with large LVMs. Korean Circulation J 2002;3212:1072-1077 KEY WORDSHypertrophy, left ventricularradionulcide imagingechocardiography. 1072
서론 대상및방법 대상 방법 - - Fig. 1. Echocardigraphic measurement of LV mass using M-mode technique. LV mass g0.80\1.04ist PWTLVID 3 -LVID 3 0.6. ISTinterventricular septal thickness, PWTposterior wall thickness, LVIDleft ventricular internal diameter. Table 1. Comparison between LV masses measured by M-mode echocardiography and by gated myocardial perfusion SPECT MeanSD g Range g LVMEcho 15749* 54298 LVMSPECT 13323* 96222 p0.001 by wilcoxon signed ranks test, LVMEcho LV mass measured by M-mode echocardiography, LV- MSPECTLV mass measured by gated myocardial perfusion SPECT 1073
통계처리 결과 고찰 Fig. 3. Comparsion between LV masses measured by gated myocardial perfusion SPECT and by M-mode echocardiography. p0.001, LVleft ventricular. Fig. 2. Correlation between LV masses measured by gated myocardial perfusion SPECT and by M-mode echocardiog-raphy. LVleft ventricular. 1074 Fig. 4. Correlation between LV mass measured by M- mode echocardiography and diff erence of LV masses, measured by M-mode echocaridography and gated myocardial perfusion SPECT. LVleft ventricular. Korean Circulation J 2002;3212:1072-1077
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