PROGRAM 줄기세포, 성장인자로 피부의 기적을 일으키다 GMBIO Inc. 서울시 도봉구 마들로 11길20, 3층(창동 농협유통센터) (서울시 도봉구 벤처기업 제1창업 보육센터 제304호) TEL 070-8706-3020 FAX 02-3491-8575 SITE GMBIO Inc.
Cellapy란? Cell + Therapy의 합성어로 검증된 줄기세포배양액. 성장인자, 펩타이드를 이용한 세포의 재생합성능력을 키워서 피부재생, 콜라겐합성, 상처치유, 피부톤개선, Cellapy 장점 2,000여곳 피부과, 성형외과 입점 레이져단독 치료 단점 보완, 토탈케어, 타병원과의 차별화 아토피, 탈모치료 등을 유도하는 새로운 피부과학적 치료입니다. CE인증 및 특허 & INCI 등록 All -in -One 미백 재생 탄력 주름 성장인자, 펩타이드 최다 특허출원 및 보유 / 국제화장품 원료집에 최다 성장인자, 펩타이드 등재 아토피 탈모 모발, 피부치료 모발성장촉진펩타이드 상표등록증 상피세포성장 융합단편펩타이드 피부상태개선 및 치주질환 간단한 시술과정(MTS, Stamp, FNS통한 약물침투) 1 1차 클렌징 / 딥클렌징 2 OPTION(레이저, 필링, 시술 등) 3 MTS 셀라피시술 4 크라이오셀 셀라피 진정 5 줄기세포 진정마스크 6 재생레이저 EGF,bFGF, KGF등 다양한 성장인자는 이미 전문의약품으로 한국,일본, 미국 등 에 허가 되었고 향후 많은수의 성장인자 펩타이드가 전문의약품 인정을 위한 임상실험 진행 중이며 또한 예정입니다. 고순도 고활성도 성장인자 98% 이상의 고순도 모든 성장인자, 펩타이드 앞에 CG(케어젠) 고유명사 표시되는 유일한 원료 Cellapy 차별화 포인트 더블 캡슐레이션 치료효과 UP 토탈케어 차별화 포인트 VIP창출 고객창출 피부전달 시스템(Double Llayered Capwulation Technology) 피부세포간극(70~180 )보다 작은사이즈(평균 140 )로 흡수율을 최대화하였으며 이중막 구조의 높은 안정성과 극대화시킨 유효성분의 수용력 'RXEOH /D\HU Cellapy 대표 프로그램 유효성분의 피부 층간 전달과 위치 3KRVSKROLSLG PROHFXOH K\GURSKLOOLF SRODU KHDG 1. 줄기세포 토닝(미백) 02 2. 줄기세포 안티에이징 3. 줄기세포 모공, 흉터 등 4. 줄기세포 탈모치료 K\GURSKRELF QRQSRODU IDWW\ DFLG WDLO 리포좀 처리된 크림을 바른 후 펩타이드에 FITC부착. 마우스의 피부단면에서 녹색 형광이 관찰됨. 03
Anti-pigmentation 재생, 안티에이징, 흉터, 모공치료 근거데이터 Skin Rejuvenation / Anti-aging MELANOGENESIS VS ANTI-PIGMENTATION MECHANISM OF CG-TGP2 GROWTH FACTORS STIMULATE FIBROBLAST PROLIFERATION GROWTH FACTORS STIMULATE FIBROBLAST PROLIFERATION CG-EGF 1ppm CG-bFGF 1ppm CG-EGF 1ppm + CG-bFGF 1ppm CG-EGF 1ppm CG-bFGF 1ppm 1. CG-ASP BLOCKSα-MSH BINDING TO MC1R Decrease melanin synthesis and tyrosinase activity in skin melanocyte 2. CG-TGP2 AND CG-PURILUX INDUCE MITF DEGRADATION Decrease melanosome transferring to keratinocytes CG-EGF 1ppm + CG-bFGF 1ppm Cell morphology changed after 72hr incubation with CG-IDP5 in the condition of serum free medium. Melanin Activity Increased cell Proliferation was abserved in fibroblast cell by CG-EGF and CG-bFGF treatment. In addition, CG-EGF and CG-bFGF Combination showed synergy effect compared with single ingredient treatment. EGF단독 치료보다 bfgf와의 복합시술시 상승효과가 탁월한 -> MGF시술 권장사항에 대한 근거 Tyrosinase Activity T]WLG T\\LG $PO 5(1 $PO 5(1 $PO 5(1 $PO 5(1 Inhibition of Melanosome Transfer 2. CG-EGF Modulates the Skin Rejuvenation by stimulation of cell Proliferation. Phenotypic appearance of melanosome transfer in cocultured cell lines with melanocytes (B16F10) and keratinocyte (HacaT). Representative morphologies of co-cultures were observed under microscopy (X 100) which was exposed for 4 days with 200ng/ α-msh and 30 / CG-TGP2. 3. CG-bFGF Modulates the Skin Rejuvenation by stimulation of cell Proliferation. &21752/ &* 7*3 ³ 06+ ³ 06+ &* 7*3 CG-TGP2 Inhibits Melanin Synthesis Cell growht assay with HaCaT Keratinocyte cell line after CG-bFGF treatment for 72hrs. Cell growht assay with fibtoblast cell line after CG-EGF treatment for 72hrs. 2. CG-EGF Modulates the Skin Rejuvenation by stimulation of cell Proliferation. CG-EGF 200pg/ml CG-EGF 200pg/m PD98059 3. Morphological Change of Fibroblast Cell. CG-TGP2 Inhibits Expression of Melanogenesis Markers Cell growht assay with HaCaT Keratinocyte cell line after CG-bFGF treatment for 72hrs. CG-bFGF 200pg/ml Phospho ERK2 Phospho ERK1 Concentration of CG-TGP2(ug/ml) CG-bFGF 200pg/m TRP1 Cell Morphology changed after 72hrs of incubation with CG-EGF in the condition of serum free medium. Cell Morphology changed after 72hrs of incubation with CG-EGF in the condition of serum free medium. TRP2 MITF Wound Healing Mechanism Healing Effect After Surgery CG-TGP2 significantly inhibits melonin synthesis on B16 F10 melanocyte. Clinical Test of Anti-pigmentation Cream X[[]U X[[]Uv Actin The effect of CG-TGP2 on melanogenesis. Phospha ERK 1/2 were increased by treatment of CG-TGP2. TRP1, TRP2 and MITF were decreased by treatment of CG-TGP2. Colorimetric Measurement i h Aged pigments and spots were decreased after using antipigmentation creamfor 8 weeks. Morphology Comparison Wound healing and scar repairing 상처치유및흉터개선 상처치유는세포복구의관점에서항노화와유사함. 성장인자가 Wound healing, repair에 주된 영향을 미치는 수많은 의학적 논문자료가 존재함. Wound healing 관여하는 성장인자 - EGF, VEGF, bfgf, RGF, KGF, PDGF 04 / YDOXH 수술1주후부터수술부위피부봉합 테이프위에매일1회, 2주간제품사용. 상처의빠른치유와흉터개선효과 Melanosome was decreased by CG-TGP2 treatment on B16F10 melanocyte. 50 5 X 5 X L value was increased after using anti-pigmentation cream for 8 weeks. 05
Anti-hair loss Scalp & Alopecia Products 탈모관리 제품소개 STOP HAIR LOSS AND HAIR REGAIN MECHANISM &XWLFOH GDPDJH LQKLELWLRQ UHSDLU Epithelial cell Basal layer (Keratinocyte) Mesenchymal cell Club 675(1*7+(1 7,668( (/$67,&,7< $17, '$1'58)) Secondary germ Epidermal strand Papilla $1$9(1 2) +$,56 Secondary germ lengthens &$7$*(1 :((.6 7(/2*(1 :((.6 '(/$< +$,5 /266 New hair 352027( +$,7 *5,:7+ &*,*) &*,*) &*.*) &RSSHU 3HSWLGH &* E)*) &* +*) &* 9(*) &* 1RJJLQ &*,*) &RSSHU SHSWLGH Step 'HOD\ D SURFHVV IURP $QDJHQ WR &DWDJHQ Outer root sheath lnner root sheath Arrector pili muscle '(502 (3,'(50$/,17(5)$&( /$<(5 &2//$*(1,9 /$0,1,1 ($7/< $1$*(1 &* 7*) ³ 1st Apocrine sweat Sebaceous gland Sebum $1&+25,1* 02/(&8/(6 352'8&7,21 $QWL +DLU /RVV 6(%80 6(&5(7,21 1250$/,=$7,21 Cuticle Medulla 5227 6+($7+ &(// 352/,)(5$7,21 352/21* $1$*(1 3+$6( Cortex Melanocyte Follicle keratinocyte Dermal papilla,03529( %/22' &,5&8/$7,21 DR.Cellapy HL Cellapy HL Cellapy GALVA HL 탈모방지, 발모촉진, 굵은모발 탈모방지, 발모촉진 [이온토전용] 모발이식 후 생착율 증가, 탈모 방지 주요성분 : CG-VEGF, CG-IGF-1, CG-bFGF, Copper Tripeptide-1, Biotin, Human Adipocyte Conditioned Media Extract, Amino Acid, Minerals and Vitamin 주요성분 : CG-IGF-1, CG-bFGF, CG-VEGF, Copper Tripeptide-1, Amino Acid, Multi-Vitamin, Amino Acid and Minerals 주요성분 : Prohairin-β4, Rejuline, IDP2, IDP5 $17, )5(( 5$',&$/6 $17,,1)/$00$7,21 )2//,&/(.(5$7,12&<7( 352/,)(5$7,21 Capillaries DHT + 5 Reductase Inactivation Testosterone 2nd Step 'HUPDKHDO +/ 'HUPDKHDO +/ *HO 'HUPDKHDO 6WHP &ÍUXP +/ 'HUPDKHDO +DLU &RQGLWLRQLQJ 6KDPSRR 'HUPDKHDO +DLU 1XWULWLRQ &*,*) &* E)*) &* 9(*) &* 7*) ³ &*.*) &* +*) 3URPRWH D SURFHVV IURP 7HORJHQ WR $QDJHQ 1HZ KDLU IRUPLQJ 3DFN 'HUPDKHDO +DLU &RQFHQWUDWLQJ 6HUXP 2013년 탈모치료 New Targeting Mechanism 1. WNT/b-Catenin Signaling 활성화 : noggin, CG-WINT,Reharin,Cheverin 2. DHT induced DKK-1, BMP4 Inhibition & Anagen induction : ccg-nokkin 1.2 모두 함유된 제품은 셀라피 뿐입니다!!! Hair Concentrating Serum Hair Concentrating Sampoo Oaze Hair Beam 두피염증, 비듬, 예민성 두피개선, 발모촉진 모발두피 세정제 두피개선, 발모촉진 주요성분 : CG-IGF-1, CG-bFGF, VEGF, CG-aFGF, Prohairin-β4, Hyaluronic acid 주요성분 : Prohairin-β4, Copper Tripeptide-1, Biotin Anti-hair Loss / Hair Regain Clinical Test Data Mask R ANAVEN 90% OF HAIRS CATAGEN 1-2 WEEKS TELOGEN 1-2 WEEKS DELAY HAIR LOSS Protocol : 1 session per week Product : Dermaheal Stem C rum HL, Home care product EATLY ANAGEN PROMOTE HAIT GRIWTH 1 CG-IGF1 1 CG-IGF1 6 CG-KGF 2 Copper Peptide 3 CG-bFGF 7 CG-HGF 4 CG-VEGF 6 CG-Noggin 5 CG-TGF-a 탈모 시술 과정 5. 샴푸 06 1. 전문의 상담 2. 두피마사지 3. 두피스케일링 4. 두피 스티머 6. 산소필링 7. 메조세라피 8. MTS-프락셀 9. 레이져 마무리 07
Skin Rejuvenation & Anti-aging Products 항노화 재생관리 제품소개 시술 관리 Anti-pigmentation Products 미백관리 제품소개 시술 DR. Cellapy SR Cellapy SR DR. Cellapy Stem C rum Cellapy SB Plus 주름개선, 노화방지, 피부탄력 효과 주름개선, 노화방지, 피부탄력 효과, 모공, 흉터, 탄력, 주름 등 6ml 6pair/set 주요성분 : CG-EGF, CG-IGF-1, CG-bFGF, CG-TRX, CG-TGF-β3, CG-aFGF, Human Adipocyte Conditioned Media Extract, Niacinamide 주요성분 : CG-EGF(상처재생 치유 촉진), CG-IGF-1(얼굴 근육세포 등에 영향을 미쳐 피부탄력을 유도함), CG-bFGF(섬유에 세포분열 촉진, 콜라겐, 엘라스틴 합성 증가), CG-TRX, CG-TRX, Copper Tripeptide-1, Multi Vitamin, Amino Acid and Minerals 지방유래 줄기세포 추출물과 고농축 성장인자로 재생, 미백효과 검버섯, 기미, 주근깨피부에효과 주요성분 : CG-EGF, CG-IGF-1, CG-bFGF, CG-TRX, CG-TGF-β3, CG-aFGF, Human Adipocyte Conditioned Media Extract, Niacinamide 주요성분 : CG-TGP2, CG-ASP, Vitamin-C, Arbutin, Glycyrrhiza Glabra (Licorice) Root Extract 관리 Cellapy GALVA FAA Cellapy GEL FAA 30ml Cellapy GALVA SL Cellapy GEL SL [이온토전용] 재생)탄력개선, 주름개선, 강력한 리프팅 효과 탄력개선, 주름개선 30ml 주요성분 : EDP(정상 피부로 재생, 손상세포 복구 및 치료), Rejuline(세포감열도 감소), IDP2(콜라겐, 엘라스틴 합성 촉진, 탄력강화, 재생 및 조직 복구), EPG(콜라겐, 엘라스틴 합성이 촉진되어 피부탄력 강화), Fibramin(섬유이세포 증식, 혈액순환 촉진, 피부탄력, 재생) 주요성분 : CG-EGF, CG-IGF-1, CG-bFGF, CG-TRX, CG-aFGF, Rejuline, CG-IDP-2, Copper Tripeptide-1, Hyaluronic Acid, Adenosine, Camellia Sinensis Leaf Extract, Glycyrrhiza Uralensis(Licorice) Root Extract, Centella Asiatica Extract, Red Clover Extract [이온토전용] 모발이식 후 생착율 증가, 탈모방지 주근깨, 검버섯, 색소침착방지 등 미백효과 주요성분 : CG-TGP, CG-Purilux, CG-EPG, Arbutin, 3-O-Ethyl Ascorbic Acid, Panthenol, Ginkgo Biloba Leaf Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Citric Acid, Arginine, quinone 주요성분 : CG-TGP-2, CG-ASP, CG-TRX, Arbutin, Hyaluronic Acid, Camellia Sinensis Leaf Extract, Glycyrrhiza Uralensis(licorice) Root Extract, Ginkgo Biloba Leaf Extract, Condroitin Sulfate, Ubiquinone Q10 홈케어 Cream Plus Post Theraphy Cream 10g, 30g Mask R 진정, 재생, 보습, 영양공급, 항산화효과 주요성분 : CG-EGF, CG-IGP-1, CG-bFGF, CG-TRX, Copper peptide 홈케어 Mask W Post Theraphy Whitening Cream 30g 시술부위의 집중적인 재생, 항균, 항염효과 진정, 황산화, 보습, 피부톤개선, 색소침착방지, 영양공급효과 미백, 재생, 보습, 항산화, 피부톤개선 주요성분 : CG-EGF, CG-bFGF, CG-TRX, Copper peptide, Plant extract complex 주요성분 : CG-TGP2, CG-ASP, EDP3, Copper Tripeptide-1 주요성분 : CG-TGP2, CG-ASP, EDP3, Copper Tripeptide-1, CG-TRX Peptides for Anti- Pigmentation Growth Factors and Peptides for Anti-aging &* 7*3,QKLELWV 0HODQLQ 6\VWKHVLV *52:7+ )$&7256 67,08/$7( ),%52%/$67 352/,)(5$7,21 &/,1,&$/ 678'< )25 *52:7+ )$&725 $17, $*,1* &5($0 &21752/ &* (*) SSP &* E)*) SSP &* (*) SSP &* E)*) SSP #&'03& Ⅵ 㽒 7\URVLQDVH 䁅 ᗹ "'5&3 h OWP i OWUWXP j OWUXP koxwp l OZWP j WUWX V WUX V XW V ZW V j G GjnT{nw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w G㷌 ⓸O V P &RQWURO &* (*) Ⅵ ㅝ㲡 % ) Ⅵ 㽑 ᛥ 㷕㿾 &* 7*3 ᗩ Ⅵ 㿾 ᗹ 䐤 㐐 㢨㪼 䞐 OLP &HOO PRUSKRORJ\ FKDQJHG DIWHU KU LQFXEDWLRQ ZLWK &*,'3 LQ WKH FRQGLWLRQ RI VHUXP IUHH PHGLXP 䐤 㐐 㢨㪼 䞐 OLP { Ⅵ ㅝ㲡 % ) ㅁ 㳙 ⳅᬍㅝ 䁅 w G㷌 ⓸O V P 㷕㿾 䀽 &OLQLFDO 7HVW RI $QWL SLJPHQWDWLRQ &UHDP X[[]U X[[]Uv t t i 8FFL 8FFL j h T GaGjnT{nwY h jnt{nwy OZW V P h G G G G G G G G T G G G_G U 09
Acne Products 여드름관리 제품소개 Cellapy Products List 셀라피 제품 리스트 안티에이징 재 생 미 백 여드름 탈 모 DR.Cellapy SR DR.Cellapy SR DR.Cellapy Stem C rum DR.Cellapy HL 6ml 6pair/set Cellapy HSR Cellapy SR Cellapy SB Cellapy HSR Cellapy HL Cellapy GALVA AA Cellapy GALVA FAA Cellapy GALVA SL Cellapy GALVA AA Cellapy GALVA HL Cellapy HSR 시술 관리 노화, 여드름, 늘어진 피부에 즉각적인 효과 주요성분 : Hyaluronic Acid, CG-EGF, CG-IGF-1, CG-bFGF, CG-TRX, Copper Tripeptide-1, Multi-Vitamin, Amino Acid and Minerals Premium Solution MesoSolution Cellapy GALVA AA Cellapy GEL AA 30ml [이온토전용] 여드름 진정, 항염, 항균, 흉터 재생 피지조절, 여드름 피부, 항염, 여드름 흉터 재생 효과 주요성분 : Acetyl Decapeptide-3 (Rejuline), Oligopeptide-24 (CG-EDP3), Oligopeptide-59 (CG-Inflamin), Panthenol, Lactoferrin, Salicylic Acid, Niacinamide, Trifolium Pratense (Clover) Flower Extract, Plantago Asiatica Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Sodium Hyaluronate, Glycine Soja (Soybean) Oil, Hydrogenated Lecithin, Arginine, Nisin, Egg York Extract 주요성분 : CG-EGF, CG-bFGF, Egg York Extract, Niacinamide, Lactoferrin, Hyaluronic Acid, Camellia Sinensis Leaf Extract, Glycyrrhiza Uralensis(Licorice) Root Extract, Glycyrrhiza(Licorice)Root Extract, Red Clover Extract, Plantago Asiatica Extract, WKC Cosmetic Solution 홈케어 Mask R Mask A 진정, 재생, 보습, 영양 진정, 재생, 항염, 항균, 여드름자국완화 수분공급 각질제거 주요성분 : CG-EGF, CG-IGP-1, CG-bFGF, CG-TRX, Copper peptide 주요성분 : EDP3, Rejuline, Copper Tripeptide-1, Paoaya, AHA Dermaheal Perfect Oil Controlle T-Zone의 전문 피지조절제 주요성분 : CG-EDP3, CG-TGP2, Rejuline, Revoline3 DeAkni 10g 진정, 재생, 보습, 영양공급, 항산화효과 주요성분 : CG-EGF, CG-IGP-1, CG-bFGF, CG-TRX, Copper peptide Mask Pack Mask R Anti-Acne Mechanism Mask W Mask A Oaze Hair Beam DeAkni 10g Hair Concentrating Sampoo Hair Concentrating Serum Hair Nutrition Pack Acno occurs when the oil-secerting glands in the skin are clogged and become inglamed or infected. What cause acne 1. Dead skin cell accumuiation 2. Overactive seba ceous gland 3. Bacteria 4. Inflammation Anti-Acne Home Care 250ml Cream Plus 10g,30g Post Theraphy Whitening Cream 30g 150ml 50ml 제휴업체 리스트 Excess sebum clogs openings to hair follicles-especially those on the face, neck, chest and back. Bactaria grows in these clogged follicles. It makes blackheads or whiteheads form on the skin surface, a condition called non-inflammatory acne. Sometimes the follicle wall breakes under the pressure of this buildup. When it happens, sebum leaks into nearby tissues and forms a pustule- It is called inflammatory acne. This cam create cysts. Ruptured cysts leave temporary or permanent scars. 10 Antiinflammation Moisturizing Sebum Controlling Scar Repairing Antibacterial S K I N 세포치료 전문 물광 EGF 줄기세포 전문 S O L U T I O N 미백 전문 탈모 전문 11