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Special Issue Diabetic Retinopathy Won Ki Lee, M.D. Department of Ophthalmology The Catholic University of Korea College of Medicine Kangnam St. Mary s Hospital E mail : wklee@catholic.ac.kr Abstract R etinopathy is the most common and vision threatening ocular complication of diabetes mellitus. Epidemiologic studies have described the natural history of diabetic retinopathy, and several well designed clinical studies have demonstrated the benefits of laser photocoagulation, vitrectomy and tight metabolic control. New therapeutic trials are in progress. ut it is one of the major causes of blindness in the adult population, which suggest the importance of early diagnosis and careful follow up examination as well as proper treatment in time. Keywords : Diabetic retinopathy 616

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Special Issue A 21. Roy MS, Klein R, O Colmain J, Klein E, Moss SE, Kempen JH. The prevalence of diabetic retinopathy among adult type 1 diabetic persons in the United States. Arch Ophthalmol 2004; 122: 546-51 22. Kempen JH, O Colmain J, Leske MC, Haffner SM, Klein R, Hamman RF, et al. The prevalence of diabetic retinopathy 626

among adults in the United States. Arch Ophthalmol 2004; 122: 552-63 23. Klein R, Klein E, Moss SE, Cruickshanks KJ. The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVII. The 14 year incidence and progression of diabetic retinopathy and associated risk factors in type 1 diabetes. Ophthalmology 1998; 105: 1801-15 24. The Early Treatment Diabetic Retinopathy Study Research Group. Fundus photographic risk factors for progression of diabetic retinopathy. Early treatment diabetic retinopathy study report No 12. Ophthalmology 1991; 98: 807-22 25. The Diabetic Retinopathy Study Research Group. Four risk factors for severe visual loss in diabetic retinopathy. The third report from the DRS. Arch Ophthalmol 1979; 97: 654-5 26. Early Treatment Dabetic Retinopathy Study Report Number 19: Focal photocoagulation treatment of diabetic macular edema. Arch Ophthalmol 1995; 113: 1144-55 27. The Diabetes Control and Complications Trial Research Group. The effect of intensive diabetes treatment on the progression of diabetic retinopathy in insulin dependent diabetes mellitus. Arch Ophthalmol 1995; 113: 36-51 28. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long term complications in insulin dependent diabetes mellitus. N Eng J Med 1993; 329: 977-86 29. Sutter FK, Simpson JM, Gillies MC. Intravitreal triamcinolone for diabetic macular edema that persists after laser treatment: three month efficacy and safety results of a prospective, randomized, double masked, placebo controlled clinical trial. Ophthalmology 2004; 111: 2044-9 10. The Diabetic Retinopathy Study Research Group. Photocoagulation treatment of proliferative diabetic retinopathy. Clinical applications of DRS findings. DRS report No 8. Ophthalmology 1981; 88: 583-600 11. The Early Treatment Diabetic Retinopathy Study Research Group. Early photocoagulation for diabetic retinopathy. Early treatment diabetic retinopathy study report No 9. Ophthalmology 1991; 98: 766-85 Peer Reviewer Commentary 627