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982 (41.8) 34,478 (58.3) 141,628 (71.8) 30-39 years 240 (24.4) 12,186 (35.3) 63,859 (45.1) 40-49 years 238 (24.2) 12,685 (36.8) 53,544 (37.8) 50-59 years 198 (20.2) 6,396 (18.6) 20,580 (14.5) 60+ years 306 (31.2) 3,211 (9.3) 3,645 (2.6) 1,370 (58.3) 24,618 (41.7) 55,622 (28.2) 30-39 years 378 (27.6) 8,160 (33.2) 31,545 (56.7) 40-49 years 306 (22.3) 7,616 (30.9) 15,850 (28.5) 50-59 years 292 (21.3) 5,882 (23.9) 6,015 (10.8) 60+ years 394 (28.8) 2,960 (12.0) 2,212 (4.0) - 29 -

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KNHANES NCEP-ATP III AHA/NHLBI IDF N (%) N (%) N (%) H_WC 274 (27.9) 13 (1.3) 274 (27.9) H_TG 395 (40.2) 395 (40.2) 395 (40.2) L_HDL 553 (56.3) 553 (56.3) 562 (27.2) H_BP 354 (36.1) 411 (41.9) 411 (41.9) H_FBS 159 (16.2) 332 (33.8) 337 (34.3) MS 27.9 26.1 22.2 MS (HDL-C exclusion) 36.3 34.8 24.0 KHS H_WC 12,229 (35.5) 1,019 (3.0) 12,229 (35.5) H_TG 7,232 (37.0) 12,738 (37.0) 12,738 (37.0) L_HDL 12,738 (21.0) 7,232 (21.0) 7,251 (21.0) H_BP 12,480 (36.2) 13,272 (38.5) 13,272 (38.5) H_FBS 5,679 (16.5) 11,726 (34.0) 12,335 (35.8) MS 19.8 15.9 18.2 age adjusted* 21.8 17.4 19.8 MS (HDL-C exclusion) 36.5 33.6 35.5 age adjusted* 39.8 36.9 37.9 KMI H_WC 34,371 (24.3) 2,556 (1.8) 34,371 (24.3) H_TG 60,841 (43.0) 60,841 (43.0) 60,841 (43.0) L_HDL 19,102 (13.5) 19,101 (13.5) 19,102 (13.5) H_BP 46,277 (32.7) 46,284 (32.7) 46,284 (32.7) H_FBS 13,235 (9.3) 30,726 (21.7) 30,963 (21.9) MS 14.7 10.9 12.7 age adjusted* 17.5 13.5 15.0 MS (HDL-C exclusion) 31.5 27.6 20.1 age adjusted* 36.5 32.6 23.3-44 -

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NCEP-ATP III AHA/NHLBI IDF KNHANES N (%) N (%) N (%) H_WC 744 (54.3) 333 (24.3) 744 (54.3) H_TG 356 (26.0) 356 (26.0) 356 (26.0) L_HDL 1,034 (75.5) 1,034 (75.5) 1,040 (75.9) H_BP 304 (22.2) 396 (28.9) 396 (28.9) H_FBS 147 (10.7) 308 (22.5) 316 (23.1) MS 30.2 27.3 32.3 MS (HDL-C exclusion) 33.1 30.3 35.3 KHS H_WC 9,904 (40.2) 5,125 (20.8) 9,904 (40.2) H_TG 9,554 (22.0) 5,404 (22.0) 5,404 (22.0) L_HDL 5,404 (38.8) 9,554 (38.8) 9,561 (38.8) H_BP 6,902 (28.0) 7,553 (30.7) 7,553 (30.7) H_FBS 3,085 (12.5) 6,160 (25.0) 6,628 (26.9) MS 20.3 18.8 20.1 age adjusted* 24.4 22.7 24.2 MS (HDL-C exclusion) 28.8 27.8 40.2 age adjusted* 34.6 33.2 45.0 KMI H_WC 11,900 (21.4) 3,256 (5.9) 11,900 (21.4) H_TG 6,558 (11.8) 6,558 (11.8) 6,558 (11.8) L_HDL 12,253 (22.0) 12,253 (22.0) 12,253 (22.0) H_BP 6,952 (12.5) 6,957 (12.5) 6,957 (12.5) H_FBS 2,111 (3.8) 6,182 (11.1) 6,252 (11.2) MS 7.2 5.7 7.3 age adjusted* 17.2 14.6 17.6 MS (HDL-C exclusion) 11.9 9.2 11.5 age adjusted* 26.1 21.2 24.9-48 -

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Diagnostic criteria Number of components Men Women N % N % 0 177 18.0 168 12.3 1 273 27.8 397 29.0 NCEP-ATP III 2 258 26.3 392 28.6 3 169 17.2 269 19.6 4 86 8.8 123 9.0 5 19 1.9 21 1.5 0 157 16.0 207 15.1 1 282 28.7 461 33.7 AHA/NHLBI 2 287 29.2 328 23.9 3 178 18.1 223 16.3 4 76 7.7 114 8.3 5 2 0.2 37 2.7 0 708 72.1 626 45.7 1 10 1.0 60 4.4 IDF 1 + 1 46 4.7 242 17.7 1 + 2 94 9.6 217 15.8 1 + 3 83 8.5 169 12.3 1 + 4 41 4.2 56 4.1-50 -

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Diagnostic criteria Number of components Men Women N % N % 0 8,724 25.3 7,144 29.0 1 10,319 29.9 7,257 29.5 NCEP-ATP III 2 8,600 24.9 5,224 21.2 3 4,783 13.9 3,179 12.9 4 1,770 5.1 1,463 5.9 5 282 0.8 351 1.4 0 9,472 27.5 7,278 29.6 1 10,675 31.0 7,509 30.5 AHA/NHLBI 2 8,836 25.6 5,200 21.1 3 4,406 12.8 2,974 12.1 4 1,023 3.0 1,320 5.4 5 66 0.2 337 1.4 0 22,249 64.5 14,714 59.8 1 2,440 7.1 2,108 8.6 IDF 1 + 1 3,520 10.2 2,850 11.6 1 + 2 3,389 10.4 2,684 10.9 1 + 3 2,157 6.3 1,653 6.7 1 + 4 523 1.5 609 2.5-52 -

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Diagnostic criteria Number of components Men Women N % N % 0 45,916 32.4 31,356 56.4 1 44,469 31.4 14,178 25.5 NCEP-ATP III 2 30,398 21.5 6,106 11.0 3 15,481 10.9 2,735 4.9 4 4,703 3.3 1,056 1.9 5 661 0.5 191 0.3 0 47,129 33.3 33,276 59.8 1 47,789 33.7 13,796 24.8 AHA/NHLBI 2 31,316 22.1 5,363 9.6 3 12,661 8.9 2,218 4.0 4 2,561 1.8 815 1.5 5 172 0.1 154 0.3 0 107,257 75.7 43,722 78.6 1 5,346 3.8 4,128 7.4 IDF 1 + 1 11,025 7.8 3,715 6.7 1 + 2 11,145 7.9 2,471 4.4 1 + 3 5,682 4.0 1,246 2.2 1 + 4 1,173 0.8 340 0.6-54 -

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NCEP AHA IDF Corresponding rates NCEP-ATP III comparable rates a b c ac ab bc abc b/a c/a ac/a ab/a bc/a abc/a % % % % % % % % % % % % % Men 30-39 (years) 23.4 17.5 17.2 15.9 16.7 9.2 9.2 74.8 73.5 67.9 71.4 39.3 39.3 40-49 (years) 24.3 24.3 21.8 19.3 18.0 13.0 13.0 100.0 89.7 79.4 74.1 53.5 53.5 50-59 (years) 30.8 29.8 27.2 22.7 22.2 15.6 14.1 96.8 88.3 73.7 72.1 50.6 45.8 60+ (years) 32.3 31.7 23.2 18.6 26.4 13.4 12.7 98.1 71.8 57.6 81.7 41.5 39.3 Total 27.9 26.1 22.1 18.9 21.2 12.7 12.2 93.5 79.2 67.7 76.0 45.5 43.7 Women 30-39 (years) 10.0 7.9 10.9 9.5 7.1 6.9 6.6 79.0 109.0 95.0 71.0 69.0 66.0 40-49 (years) 18.3 12.8 19.6 17.3 10.5 10.2 9.5 69.9 107.1 94.5 57.4 55.7 51.9 50-59 (years) 34.6 32.1 38.3 32.2 29.1 29.4 26.7 92.8 110.7 93.1 84.1 85.0 77.2 60+ (years) 55.3 53.5 58.1 51.2 47.2 47.4 43.1 96.7 105.1 92.6 85.4 85.7 77.9 Total 30.1 27.2 32.2 28.1 24.0 24.0 22.0 90.4 107.0 93.4 79.7 79.7 73.1-57 -

NCEP AHA IDF Corresponding rates NCEP-ATP III comparable rates a b c ac ab bc abc b/a c/a ac/a ab/a bc/a abc/a % % % % % % % % % % % % % Men 30-39 (years) 14.3 11.7 13.7 11.4 9.0 6.4 6.2 81.8 95.8 79.7 62.9 44.8 43.4 40-49 (years) 20.6 16.5 19.0 15.9 13.1 8.9 8.6 80.1 92.2 77.2 63.6 43.2 41.7 50-59 (years) 25.6 20.6 22.3 19.0 16.9 10.7 10.4 80.5 87.1 74.2 66.0 41.8 40.6 60+ (years) 26.3 20.7 23.6 20.3 17.2 11.9 11.5 78.7 89.7 77.2 65.4 45.2 43.7 Total 19.8 16.0 18.1 15.2 12.7 8.6 8.3 80.8 91.4 76.8 64.1 43.4 41.9 Women 30-39 (years) 8.3 7.6 8.2 7.1 6.0 5.5 5.0 91.6 98.8 85.5 72.3 66.3 60.2 40-49 (years) 16.3 15.4 16.5 14.1 13.0 12.1 11.0 94.5 101.2 86.5 79.8 74.2 67.5 50-59 (years) 31.7 29.2 31.2 27.2 25.5 22.9 21.1 92.1 98.4 85.8 80.4 72.2 66.6 60+ (years) 40.8 37.9 40.2 34.8 33.2 29.9 27.3 92.9 98.5 85.3 81.4 73.3 66.9 Total 20.3 18.8 20.0 17.4 16.1 14.6 13.4 92.6 98.5 85.7 79.3 71.9 66.0-58 -

NCEP AHA IDF Corresponding rates NCEP-ATP III comparable rates a b c ac ab bc abc b/a c/a ac/a ab/a bc/a abc/a % % % % % % % % % % % % % Men 30-39 (years) 12.5 8.4 11.3 10.1 7.0 4.7 4.6 67.2 90.4 80.8 56.0 37.6 36.8 40-49 (years) 15.5 12.0 13.1 11.4 9.8 5.8 5.7 77.4 84.5 73.5 63.2 37.4 36.8 50-59 (years) 18.4 14.7 14.9 12.8 12.1 6.6 6.5 79.9 81.0 69.6 65.8 35.9 35.3 60+ (years) 22.5 17.8 19.5 16.4 15.2 9.3 9.1 79.1 86.7 72.9 67.6 41.3 40.4 Total 14.8 10.9 12.8 11.2 9.0 5.5 5.4 73.6 86.5 75.7 60.8 37.2 36.5 Women 30-39 (years) 2.6 1.9 2.8 2.4 1.6 1.5 1.4 73.1 107.7 92.3 61.5 57.7 53.8 40-49 (years) 7.0 5.5 7.1 6.0 4.4 3.7 3.4 78.6 101.4 85.7 62.9 52.9 48.6 50-59 (years) 20.3 16.1 20.0 17.7 14.4 12.5 11.8 79.3 98.5 87.2 70.9 61.6 58.1 60+ (years) 36.6 32.9 38.2 33.6 28.9 28.0 25.9 89.9 104.4 91.8 79.0 76.5 70.8 Total 7.2 5.7 7.4 6.4 4.9 4.4 4.1 79.2 102.8 88.9 68.1 61.1 56.9-59 -

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Sex Diagnostic criteria ASCVD CHD Total Stroke HR (95% CI) HR (95% CI) HR (95% CI) Men NCEP-ATP III 1.63 (1.48-1.79) 1.54 (1.10-2.14) 1.57 (1.33-1.85) AHA/NHLBI 1.63 (1.48-1.81) 1.45 (1.01-2.07) 1.79 (1.51-2.12) IDF 1.50 (1.36-1.66) 1.65 (1.18-2.31) 1.36 (1.14-1.62) Women NCEP-ATP III 1.62 (1.44-1.83) 2.22 (1.22-4.03) 1.63 (1.34-1.98) AHA/NHLBI 1.57 (1.39-1.77) 3.36 (1.83-6.17) 1.60 (1.31-1.95) IDF 1.54 (1.36-1.74) 2.32 (1.28-4.22) 1.50 (1.23-1.82) - 62 -

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Sex risk factors NCEP-ATP III AHA/NHLBI IDF HR (95% CI) HR (95% CI) HR (95% CI) Men H_WC 1.31 (1.19-1.43) 1.26 (1.01-1.58) 1.31 (1.19-1.43) H_TG 1.25 (1.14-1.37) 1.25 (1.14-1.37) 1.25 (1.14-1.37) L_HDL 1.10 (0.99-1.22) 1.10 (0.99-1.22) 1.11 (0.99-1.23) H_BP 1.60 (1.46-1.75) 1.60 (1.46-1.75) 1.60 (1.46-1.75) H_FBS 1.62 (1.47-1.79) 1.42 (1.30-1.56) 1.46 (1.34-1.60) Women H_WC 1.46 (1.30-1.65) 1.27 (1.12-1.44) 1.46 (1.30-1.65) H_TG 1.28 (1.13-1.44) 1.28 (1.13-1.44) 1.28 (1.13-1.44) H_HDL 1.24 (1.10-1.38) 1.24 (1.10-1.38) 1.23 (1.10-1.38) H_BP 1.93 (1.71-2.17) 1.93 (1.71-2.18) 1.93 (1.71-2.18) H_FBS 1.37 (1.20-1.58) 1.30 (1.15-1.46) 1.33 (1.18-1.49) - 65 -

Sex risk factors NCEP-ATP III AHA/NHLBI IDF HR (95% CI) HR (95% CI) HR (95% CI) Men H_WC 1.34 (0.98-1.82) 1.77 (0.90-3.48) 1.34 (0.98-1.82) H_TG 1.38 (1.01-1.87) 1.38 (1.01-1.87) 1.38 (1.01-1.87) L_HDL 1.29 (0.91-1.81) 1.29 (0.91-1.81) 1.28 (0.91-1.81) H_BP 1.44 (1.05-1.96) 1.38 (1.01-1.88) 1.38 (1.01-1.88) H_FBS 1.36 (0.96-1.95) 1.44 (1.06-1.95) 1.54 (1.13-2.09) Women H_WC 1.70 (0.90-3.20) 1.36 (0.74-2.51) 1.70 (0.90-3.20) H_TG 2.54 (1.41-4.58) 2.54 (1.41-4.58) 2.54 (1.41-4.58) H_HDL 1.36 (0.76-2.43) 1.36 (0.76-2.43) 1.36 (0.76-2.42) H_BP 2.15 (1.15-4.04) 2.35 (1.24-4.49) 2.35 (1.24-4.49) H_FBS 2.78 (1.53-5.08) 2.63 (1.46-4.75) 2.38 (1.32-4.29) - 66 -

Sex risk factors NCEP-ATP III AHA/NHLBI IDF HR (95% CI) HR (95% CI) HR (95% CI) Men H_WC 1.00 (085-1.17) 1.21 (0.82-1.78) 1.00 (0.85-1.17) H_TG 1.25 (1.07-1.46) 1.25 (1.07-1.46) 1.25 (1.07-1.46) L_HDL 1.01 (0.84-1.21) 1.01 (0.84-1.21) 1.00 (0.83-1.21) H_BP 1.97 (1.68-2.31) 1.93 (1.64-2.26) 1.93 (1.64-2.26) H_FBS 1.77 (1.49-2.09) 1.60 (1.37-1.86) 1.58 (1.35-1.84) Women H_WC 1.29 (1.07-1.57) 1.11 (0.90-1.36) 1.29 (1.07-1.57) H_TG 1.34 (1.10-1.63) 1.34 (1.10-1.63) 1.34 (1.10-1.63) H_HDL 1.30 (1.08-1.56) 1.30 (1.08-1.56) 1.29 (1.07-1.56) H_BP 2.08 (1.70-2.53) 2.16 (1.77-2.64) 2.16 (1.77-2.64) H_FBS 1.39 (1.11-1.74) 1.21 (0.99-1.47) 1.19 (0.98-1.44) - 67 -

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All NCEP-ATP III AHA/NHLBI IDF (%) (%) (%) (%) All 17.9 29.1 61.5 26.7 67.0 28.0 63.9 Men 12.2 27.9 43.7 26.1 46.7 22.1 55.2 Women 22.0 30.1 73.1 27.2 80.9 32.2 68.3 (KNHANES) years All NCEP-ATP III AHA/NHLBI IDF (%) (%) (%) (%) 30-39 9.2 23.4 39.3 17.5 52.6 17.2 53.5 40-49 13.0 24.3 53.5 24.3 53.5 21.8 59.6 50-59 14.1 30.8 45.8 29.8 47.3 27.2 51.8 60+ 12.7 32.3 39.3 31.7 40.1 23.2 54.7-88 -

(KNHANES) years All NCEP-ATP III AHA/NHLBI IDF (%) (%) (%) (%) 30-39 6.6 10.0 66.0 7.9 83.5 10.9 60.6 40-49 9.5 18.3 51.9 12.8 74.2 19.6 48.5 50-59 26.7 34.6 77.2 32.1 83.2 38.3 69.7 60+ 43.1 55.3 77.9 53.5 80.6 58.0 74.3 (KNHANES) years NCEP-ATP III AHA/NHLBI NCEP-ATP III IDF AHA/NHLBI IDF (%) (%) (%) (%) (%) (%) 30-39 16.7 23.4 71.4 17.5 95.4 15.9 23.4 67.9 23.8 66.8 9.2 17.5 52.6 23.8 38.7 40-49 18.0 24.3 74.1 24.3 74.1 19.3 24.3 79.4 26.9 71.7 13.0 24.3 53.5 26.9 48.3 50-59 22.2 30.8 72.1 29.8 74.5 22.7 30.8 73.7 29.8 76.2 15.6 29.8 52.3 29.8 52.3 60+ 26.4 32.3 81.7 31.7 83.3 18.6 32.3 57.6 27.5 67.6 13.4 31.7 42.3 27.5 48.7-89 -

(KNHANES) years NCEP AHA NCEP IDF AHA IDF 30-39 7.1 10.0 71.0 7.9 89.9 9.5 10.0 95.0 27.5 34.5 6.9 7.9 87.3 27.5 25.1 40-49 10.5 18.3 57.4 12.8 82.0 17.3 18.3 94.5 37.9 45.6 10.2 12.8 79.7 37.9 26.9 50-59 29.1 34.6 84.1 32.1 90.7 32.2 34.6 93.1 61.3 52.5 29.4 32.1 91.6 61.3 48.0 60+ 47.2 55.3 85.4 53.5 88.2 51.2 55.3 92.6 72.3 70.8 47.4 53.5 88.6 72.3 65.6 (KHS) All NCEP-ATP III AHA/NHLBI IDF (%) (%) (%) (%) All 10.4 20.0 52.0 17.1 60.8 18.9 55.0 Men 8.3 19.8 41.9 16.0 51.9 18.1 45.9 Women 13.4 20.3 66.0 18.8 71.3 20.0 67.0-90 -

(KHS) years All NCEP-ATP III AHA/NHLBI IDF (%) (%) (%) (%) 30-39 6.2 14.3 43.4 11.7 53.0 13.7 45.3 40-49 8.6 20.6 41.7 16.5 52.1 19.0 45.3 50-59 10.4 25.6 40.6 20.6 50.5 22.3 46.6 60+ 11.5 26.3 43.7 20.7 55.6 23.6 48.7 (KHS) NCEP-ATP III All years AHA/NHLBI IDF (%) (%) (%) (%) 30-39 5.0 8.3 60.2 7.6 65.8 8.2 61.0 40-49 11.0 16.3 67.5 15.4 71.4 16.5 66.7 50-59 21.1 31.7 66.6 29.2 72.3 31.2 67.6 60+ 27.3 40.8 66.9 37.9 72.0 40.2 67.9-91 -

(KHS) years NCEP-ATP III AHA/NHLBI NCEP-ATP III IDF AHA/NHLBI IDF (%) (%) (%) (%) (%) (%) 30-39 7.8 11.8 66.1 10.0 78.0 9.6 11.8 81.4 11.4 84.2 6.0 10.0 60.0 11.4 52.6 40-49 13.0 19.0 68.4 16.0 81.3 15.3 19.0 80.5 18.2 84.1 10.1 16.0 63.1 18.2 55.5 50-59 21.0 28.5 73.7 24.7 85.0 22.9 28.5 80.4 26.5 86.4 16.5 24.7 66.8 26.5 62.3 60+ 24.9 33.3 74.8 29.0 85.9 27.3 33.3 82.0 31.7 86.1 20.6 29.0 71.0 31.7 65.0 (KHS) years NCEP-ATP III AHA/NHLBI NCEP-ATP III IDF AHA/NHLBI IDF (%) (%) (%) (%) (%) (%) 30-39 6.0 8.3 72.3 7.6 78.9 7.1 8.3 85.5 8.2 86.6 5.5 7.6 72.4 8.2 67.1 40-49 13.0 16.3 79.8 15.4 84.4 14.1 16.3 86.5 16.5 85.5 12.1 15.4 78.6 16.5 73.3 50-59 25.5 31.7 80.4 29.2 87.3 27.2 31.7 85.8 31.2 87.2 22.9 29.2 78.4 31.2 73.4 60+ 33.2 40.8 81.4 37.9 87.6 34.8 40.8 85.3 40.2 86.6 29.9 37.9 78.9 40.2 74.4-92 -

(KMI) All NCEP-ATP III AHA/NHLBI IDF (%) (%) (%) (%) All 5.0 12.6 39.7 9.4 53.2 18.7 26.7 Men 5.4 14.8 36.5 10.9 49.5 20.5 26.3 Women 4.1 7.2 56.9 5.7 71.9 14.0 29.3 (KMI) years All NCEP-ATP III AHA/NHLBI IDF (%) (%) (%) (%) 30-39 4.6 12.5 36.8 8.4 54.8 19.0 24.2 40-49 5.7 15.5 36.8 12.0 47.5 20.7 27.5 50-59 6.5 18.4 35.3 14.7 44.2 22.7 28.6 60+ 9.1 22.5 40.4 17.8 51.1 30.2 30.1-93 -

(KMI) All NCEP-ATP III AHA/NHLBI IDF years (%) (%) (%) (%) 30-39 1.4 2.6 53.8 1.9 73.7 7.0 20.0 40-49 3.4 7.0 48.6 5.5 61.8 14.5 23.4 50-59 11.8 20.3 58.1 16.1 73.3 33.7 35.0 60+ 25.9 36.6 70.8 32.9 78.7 55.2 46.9 (KMI) years NCEP-ATP III AHA/NHLBI NCEP-ATP III IDF AHA/NHLBI IDF (%) (%) (%) (%) (%) (%) 30-39 7.0 12.5 56.0 8.4 83.3 10.1 12.5 80.8 19.0 53.2 4.7 8.4 56.0 19.0 24.7 40-49 9.8 15.5 63.2 12.0 81.7 11.4 15.5 73.5 20.7 55.1 5.8 12.0 48.3 20.7 28.0 50-59 12.1 18.4 65.8 14.7 82.3 12.8 18.4 69.6 22.7 56.4 6.6 14.7 44.9 22.7 29.1 60+ 15.2 22.5 67.6 17.8 85.4 16.4 22.5 72.9 30.2 54.3 9.3 17.8 52.2 30.2 30.8-94 -

(KMI) years NCEP-ATP III AHA/NHLBI NCEP-ATP III IDF AHA/NHLBI IDF (%) (%) (%) (%) (%) (%) 30-39 1.6 2.6 61.5 1.9 84.2 2.4 2.6 92.3 7.0 34.3 1.5 1.9 78.9 7.0 21.4 40-49 4.4 7.0 62.9 5.5 80.0 6.0 7.0 85.7 14.5 41.4 3.7 5.5 67.3 14.5 25.5 50-59 14.4 20.3 70.9 16.1 89.4 17.7 20.3 87.2 33.7 52.5 12.5 16.1 77.6 33.7 37.1 60+ 28.9 36.6 79.0 32.9 87.8 33.6 36.6 91.8 55.2 60.9 28.0 32.9 85.1 55.2 50.7-95 -

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