Physiological tremor Enhanced physiological tremor Essential tremor syndrome Dystonic tremor syndrome Parkinsonian tremor Cerebellar tremor Holmes tre

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1 Journal of the K. S. C. N. Vol. 1, No. 2 The Classification and Electrophysiological Evaluation of Tremor Man-Wook Seo, M.D. Department of Neurology, College of Medicine, Chonbuk National University - Abstract - Tremor is an approximately rhythmic, roughly sinusoidal involuntary movement. Despite nearly a century of modern clinical and laboratory investigations, no tremor is understood completely. Human tremors derive from different etiologies and thus, not suprisingly, the physiologies are diverse. Tremors may derive from mechanical oscillations, mechanical reflex oscillations, normal central oscillators, and pathologic central oscillators. However the definitive identification of oscillators for any tremor have not yet been established. Measuring tremor clinically is difficult because tremors behave in different and often complex ways. There are several different techniques for measuring tremor. One of most popular and sensitive methods use accelerometries. An excellent method consists of accelerometry and EMG combined with spectral analysis and weighting of the body part, which allows separation of tremors coming from mechanical reflex and central oscillators. Now times, increased power and speed of microprocessors enable clinical laboratories to quantify tremor and other aspects of motor disability with accuracy and precision not possible a decade ago. Key Words : Tremor, Pathophysiologic mechanisms, Electrophysiological tests 270 Journal of the K. S. C. N. 1999

2 Physiological tremor Enhanced physiological tremor Essential tremor syndrome Dystonic tremor syndrome Parkinsonian tremor Cerebellar tremor Holmes tremor Palatal tremor Neuropathic tremor Drug-induced and toxic tremor Psychogenic tremor Others 271

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4 Mechanical systems Graphic digitizing tablets Electromyography Long term EMG Fourier analysis of tremor Advanced methods of time series analysis Three-dimensional analysis of tremor curves Reflex testing Activation patterns of ballistic movements Single motor unit recording Median nerve SEPs, jerk-locked averaging and EEGs Magnetoencephalography Others 273

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Pharmacotherapeutics Application of New Pathogenesis on the Drug Treatment of Diabetes Young Seol Kim, M.D. Department of Endocrinology Kyung Hee Univ

Pharmacotherapeutics Application of New Pathogenesis on the Drug Treatment of Diabetes Young Seol Kim, M.D. Department of Endocrinology Kyung Hee Univ Application of New Pathogenesis on the Drug Treatment of Diabetes Young Seol Kim, M.D. Department of Endocrinology Kyung Hee University College of Medicine & Hospital E mail : ycell2@yahoo.co.kr Abstract