:,, : 1 ) * ** ** *** *** ***. 1.. - - (Mit zel- Wilk in son, 200 0 ; Snyder & Lin dqu ist, 1998 ). (AHNA) 199,,,,, (Lim et al., 2000 ). 97 5.1, 53.1 77 2 0-30 %., (P ar k & Su h, 19 96 ; Lee, S. Y. et al., 20 0 1).,, (Baldr ee, Mu r ph y & P ower, 1982 ; Lee et a l., 200 1),. (psych on eu - r oimm u n ology ) (Cau dell, 199 6 ), Eisenber g (199 8 ), (Lim et al, 20 00 ), (Ch ia, 19 96 ; Mit zel- Wilk in son, 2 000 )., Snyder Lin dqu ist (199 8 ).,,,,, (Baik, 199 9 ; Kim, 200 0 ) 1) 2 0 0 1 * ** *** 2 0 0 2 3 2 7 2 0 0 2 6 2 0 2 0 0 2 8 12-7 16 -
3 2 5,.. 2.. 1). 1 :. 2 :. 2 ). 3 ). 3. 1). (Car t er & Web er, 2 000 ). Car t er Weber (20 00 ) r eflexology Ch ia (199 5) Ch i- m a ssa ge Oh (2 00 1) -,, (int er a ct ive gu ided im a gery ). 2 ). ( ),,, (Lee, 199 1), Sh in (19 96 ) (Oh, 200 1 ). Lee (199 2 ) Vigor Sh in Oh (2 00 1)..,,.. 1., (Lee et a l., 200 1)., ' ', 5 %, (Ba ldr ee et al, 19 82 ).,,, (Daich ou, Ku r a sh ige, H a sh u m ot o & Su zu k i, 1999 ; Lee et a l., 2 00 1). T, polyam in e. B C3 (Cor dova, Ben ab e & Ma rt in ez- Mald on a do, 199 1). B T, T lym ph ok in e T (Daich ou et a l., 19 99 ; Ra sk ova, Gh bria l, Sh ea, Elsin ger & Ra sk a, 198 ).,. - 7 17 -
2 0 0 2 10 (P a rk & Su h, 199 5 ). (Sh ik e, 1996 ). DNA, CD, T.,,,, (Appleb au m, 199 2 ).. 93.6 %, 5.7 % (Ya n g, Kwon & Kim, 20 0 1). Tonin i (19 98 ) 10 9-2 -,. T (Kiecolt et a l., 19 8 5 ; O' Lear y, 199 0 ).,,,. 3. (r eflexology) 10. ca lciu m a cid (Ca rt er et al, 2 000 ). H ea d ' zon e m a ssa ge F it zger ald (19 13 ) (h a n d zon e t h er a py ) In gh am (19 57 ) foot r eflexology (Byer s, 19 8 ).,,,,, (Car t er et a l., 2 000 ). (Ch ia, 199 6 ).,,,,, (Byer s, 198 ).. - 6-9 5-7 (cat er pillar t ech niqu e). 1-2... (Car t er et al, 20 00 ). 1.. <Figu r e. 1>. b efor e in t ervent ion aft er Exp er im ent a l G Ye 1 X Ye 2 Con t r ol G Yc 1 - - - -- Yc 2 Y : Da t a collect ion X : Experim ent a l in t ervent ion 2. <F ig u re 1> Re s e a rc h d es ig n 3., - 7 18 -
3 2 5 32, 30 1 7 3 1, 23 5. 3. 30 gm 2.7Kg 7 1 (Car t er et al., 2 000 ), 10 1-2.2Kg ( ) -,, (IGI). 3, (Snyder et al., 1998 ; Lee, 20 00 ), m it ogen 3 (Kwon et al., 19 98 ). P ark (19 96 ) Oh (200 1) 5 5, 3 5. Oh (200 1) 10. 20 0 1 7 10 10 20 9, 11-12.,,,, 5. 2.. 1) :,,. Br au n ( ) Th er m osca n IRT 102 0, Om r on F 2 ( ), XE2 100. 2 ) : Lee (19 9 1) Oh (2 00 1) 0-10. (6 ) Lee (19 9 1) Cr on ba ch ' s a lph a.9.70, (8 ) Oh (20 0 1) Cr onba ch ' s alph a.9 5.9 3. 3 ) : T, B, N K, T, T, h/ s r a t io CD, CD8, CD 16, CD 19 MCD ( CD3 1, CD32, CD33, CD3 ). Bect on Dickin son ( ) T3, T, T8, T 16, T 19, T 59 F low cyt om et r y. 5. SP SS/ P C 10.0 0.0 5, ²- t est, t - t est. t - t est, p air ed t - t est.. 1. 2 9 (53.7 % ) 2 5 ( 6.3 % ), 28 (5 1.9 % ), 26 ( 8.1% ). 9 (90.8 %), 3 5 (6.8 %).. 3 (77.8 %),. 20 72 53.3, 50. 5 1.9± 13.3. 2 2 2.5, 3.8.2±5.7, - 7 19 -
2 0 0 2 10 <T a b le 1> Ho m o g e n e ity t e st ( - t es t ) f o r c h a ract e rist ics b etw e e n ex p e rim e nt a l a n d co nt ro l g ro u p (N = 5 ) Su bj ect N (%) Experi. G. Cont r ol G. P P at ient CRF 2 9 ( 53.7 ) 16 13 Ca 2 5 ( 6.3 ) 15 10.128.7 9 Gen der m ale 2 8 ( 5 1.9 ) 17 1 fem a le 2 6 ( 8. 1) 1 12.2 60.7 8 Age u n d er 5 0 2 1 ( 38.9 ) 1 1 10 ab ove 5 1 3 3 ( 6 1. 1) 2 0 13.3 55.5 8 Religion pr ot est a nt 17 ( 3 1.5 ) 8 9 cat h olic 5 ( 9.3 ) 3 2 bu ddh ism n on e 2 1 ( 38.9 ) 10 ( 18.5 ) 1 6 7.0 3.5 7 ot h er s 1 ( 1.8 ) 0 1 Mar it a l st at u s Ad dr ess Ca r e giv er J ob Econ om ic st at u s Edu ca t ion u nm a rr ied m ar ried ot h er s cit y cou nt ry sp ou se fa m ily ot h er s n on e yes h igh m iddle lower n on e elem ent a l m iddle- h igh ov er college 5 ( 9.3 ) 2 ( 77.8 ) 7 ( 13.0 ) 3 2 ( 59.3 ) 2 2 ( 0.7 ) 3 5 ( 6.8 ) 13 ( 15. 1) 6 ( 11. 1) 3 2 ( 59.3 ) 2 2 ( 0.7 ) ( 7. ) 6 ( 85.2 ) ( 7. ) 5 ( 9.3 ) 7 ( 13.0 ) 2 2 ( 0.7 ) 2 0 ( 37.0 ) 1 2 6 16 15 2 1 6 17 1 2 3 3 6 9 13 16 3 16 7 1 7 2 15 8 0 2 3 0 2 1 13 7 Tot al 5 (100.0 ) 3 1 (10 0.0 ) 2 3 (10 0.0 ) 3.20 9.2 0 1.76 3.15.9 80.6 1.5 89.3 1 6. 18 3.7 5.26 6.15 1 9 1.7 ±2., 1 5 1.1± 1.32. ²- t est <Table 1>. 2. 1) 1 : 1 2. 1 :, 1-0.1 ±0.2 7 C 0.0 ±0.29 C (p =.03 ). - 5.2 ±.8 7 / (p =.0 00 ), - 19.0± 17.37mm H g (p =.0 00 ). - 12.0 ± 13.3 m m H g. 5-0.20 ±0.3 7 C 0.0 9±0.3 3 C (p =.00 5 ),, <Table 2 >. 2 : <Ta ble 3 >.28±.6m g/ dl, -.30±.78m g/ dl (p =.0 0 ). 1. 2 ) 2 : <Table 3 >. - 7 2 0 -
3 2 5 <T a b le 2 > Ch a ng e o f v it a l s ig ns aft e r 1s t a n d 5t h inte rv e nt io n BT ( C) P R (n/ m in ) Sys. P (m m Hg) Dia. P (m m Hg) exp (n = 3 1) Differ en ce Differ en ce a ft er # 1st In t. t p a ft er # 5t h Int. t p con (n = 23 ) Mea n (SD ) Mea n (SD) Exp -. 1 ±.27 -.2 0 ±.37-2.32.03 Con t r ol.0 ±.29.0 9 ±.33-2.90.00 5 Exp - 5. 19 ±.87-6.9 0 ± 8.3 -.96.000 Con t r ol - 1.6 1± 5. 13-2.7 ± 1. 3-1.3. 19 Exp - 19.0 ± 17.3 7-6. 2 ± 15.0 6-3.80.000 Con t r ol.87 ±2 1.0 3 1.9 1 ±20.8 5-1.7 1.09 Exp - 12.0 ± 13.3-2.90 ± 11.3 1-1.72.09 Con t r ol -.57 ± 18. 2.65 ±35. 2-1.08.09 <T a b le 3 > Co m p a ris o n of Hb a n d e m ot io n a l res p o ns es b ef o re a n d aft e r inte rv e nt io ns exp (n = 3 1) b efor e aft er Differ en ce t p (aft -b efor e) t p con (n = 23 ) Mea n (SD ) Mea n (SD) Mea n (SD ) Hb Exp 10.10± 1.6 2 10.3 9± 1.7 8 2. 8.02.2 8 ±.6 (m g/ dl) Con t r ol 10.2 9± 2.0 9.98 ± 1.87-1.87.07 -.3 0 ±.78 3.05.00 vigor Exp 3 1.5 ± 15.3 37.0 ± 13.5 2.39.02 5.53 ± 12. 8 (scor e) Con t r ol 32.5 ± 10.9 3 1.0 ± 10.9 -.98.3-1.5 2 ± 7.5 1 2.39.02 m ood Exp 0.5 ± 1.8 5.0 ± 17.0 6.79.00 0 13.5 2 ± 1 1.08 (scor e) Con t r ol 5.9 ± 15.9 1. ± 1.8-1.95.06 -. 8 ± 10.9 9 5.92.000 t = p air ed t - t est, t = in d ep en dent t - t est 5.53± 12. 8 (p =.02 ), 13.52 ± 1 1.08 (p =.00 0 ) 2. <T a b le > A n a ly s is o f t h e im m u n e ce lls b ef o re a n d aft e r inte rv e nt io n exp (n = 3 1) b efor e a ft er differ en ce t p (a ft - b efor e ) t p con (n = 23 ) Mea n (SD ) Mea n (SD) Mea n (SD ) Lym p Exp 2 2.58± 10.89 17.2 1± 9.2 0-2.7 1.0 1-5.37 ± 11.0 2 (% ) Con t r ol 2.80± 15. 6 18.9 2± 12.27-2.9 6.007-5.88 ± 9.53 -.18.86 T cell Exp 6 8.32± 11.23 65.7 9± 1.23-1.3 1.20-2.53 ± 10.7 7 (% ) Con t r ol 7 3. 19± 12.5 1 73.1 ± 1 1.50 -.0 3.98 -.0 ± 6.87-1.0 3.3 1 B cell Exp 1 1.50± 7. 18 16.19± 1 1.52 2.9.006.69 ± 8.89 (% ) Con t r ol 7.3 5± 5. 7.0 7± 3. 1 -. 8.6 -.28± 2.83 2.9 2.006 N K cell Exp 2 0. 17± 7.99 17.7 1± 9.2 6-1.6 2. 12-2. 7 ± 8.50 (% ) Con t r ol 19. 8± 10.60 19.8 0± 9.6 9.2 3.8 1.33± 6.7-1.3 0.20 h/ s r at io Exp 1. 5±.7 1 1.5 3±.72.7 6. 6.07±.5 5 Con t r ol 1.2 0±.62 1.2 3±.6 1.3 3.75.02±.3 2..66 T cell Exp 8 9.8 ±575.3 7 5 1.7 ± 32.7-1.6 7. 11-1 3. 1 ± 76.7 (n/ ) Con t r ol 9 06.7 ± 13.9 8 56. 1 ± 86.7 -.6 6.5 1-50.6 1±366.2 -.7 8. Th Exp 5 0.5 ±322.2 8.7 ±285.2 -.9 7.3-55.8 1±32 1.9 (n/ ) Con t r ol 83.2 ±269.9 5 1.6 ±295.9 -.7 5. 6-3 1.6 1±20 1.2 -.3 2.75 Ts Exp 3 97.7 ±309.0 3 10.9 ± 19 1. - 2.2 3.03-86.7 ±2 16.9 (n/ ) Con t r ol 2.7 ±2 13.0 26.9 ±262.5 -.3 8.70-15.7 0± 197.5-1.2.22 B cell Exp 139.8 ± 100.2 186.0 ± 156.8 2.1 1.0 6.2 3± 122.3 (n/ ) Con t r ol 8.5 ± 6 8. 15 7.9 ± 70.0-1.5 5. 1-9.6 1±2 937 5 2. 5.02 N K cell Exp 2 52. ± 1 1.2 188. ± 1 2.5-2. 0.02-6.0 3± 1 8.7 (n/ ) Con t r ol 2 38.8 ± 157.3 2 1.3 ± 125.9 -.9 2.37-2.5 7± 127.8-1.0 2.3 1 t = p air ed t - t est, t = in d ep en dent t - t est, Th ; h elp er T cell, Ts ; su p pr essor T cell - 7 2 1 -
2 0 0 2 10 3 ) 3. : <Table > <Table 5>. T, N K. B (.69 ±8.8 9 % ) ( 6.23± 12 2.3/ ) (p =.006, p =.02 ). (CD ) CD 19 (.9 ±8.9 1/ ) (p =.00 8 ), CD8 CD 16 <Ta ble 5 >. 3.. 1. 10,,. 5 (Oh, 20 0 1). 10 (Ch oe, Oh D. & Oh S., 200 0 ). (TT ), (Ra n dolph, 19 8 ), Ch oe (200 0 ) 2 0, Lee (200 0 ) 3., (Oh, 20 0 1, Snyder et a l., 1998 )., (19 98 ) (200 0 ), (Oh, 20 0 1 ), Oh (200 0 ), P a rk (19 9 5) 5.. (P ar k & Su h, 199 5 ), Oh (20 00 ) 5. (Birk et a l., 200 0 ; Lee, 2 000 ). Su sa n (199 8 ) 1 (Baik, 1999 ), Ba ik (199 9 ), <T a b le 5 > A n a ly s is o f CD b ef o re a n d aft e r inte rv e nt io n exp (n = 3 1) b efor e a ft er differ en ce t p (a ft - befor e ) t p n/ con (n = 23 ) Mea n (SD ) Mea n (SD ) Mea n (SD) CD Exp 37.3 ± 9.0 37.6 ± 1 1.9. 1.8 9.3 2 ± 12.69 Cont r ol 36. ± 1 1.5 1 36.0 ± 12.6 -.29.7 7 -.3 9 ± 6. 2.2 7.79 CD8 Exp 29.1 ± 10.2 28.1 ± 9.0-1. 13.2 7-1.03 ± 5.09 Cont r ol 3.3 ± 10.5 3.2 ± 1 1. 1 -. 10.9 2 -.0 9 ±.3 1 -.7 2. 8 CD 16 Exp 19.2 ± 7.3 17.5 ± 9.2-1. 12.2 7-1.68 ± 8.35 Cont r ol 18.8 ± 10.8 19.6 ± 10.3.6 1.5 5.8 3 ± 6.5-1.19.2 CD 19 Exp 11.7 ± 7.0 16.0 ± 1 1. 3.09.0 0.9 ± 8.9 1 Cont r ol 7. 1 ± 5.5 7.2 ± 5.8. 13.9 0.0 9 ± 3.23 2.7 9.00 8 MCD Exp 65.6 9± 12. 1 6.5 ± 1.62 -.56.5 8-1. 15 ± 11. 7 Cont r ol 69.0 ± 1 1.23 68.2 7± 10.75 -.57.5 8 -.7 7 ± 6.55 -.15.88 t = p air ed t - t est, t = in d ep en dent t - t est, MCD = Mea n of CD3 1, CD32, CD33, CD3-7 2 2 -
3 2 5, (Kim, 2 000 ). TT Hb (Ra n dolph, 188 ). Hb (Sh ik e, 199 6 ; Ya n g, 200 1), (Lee et a l., 20 0 1). 2. (Byer s, 19 8 ; Car t er et al., 20 00 )., (Ca u dell, 1996 ; Snyder et a l., 1998 ). N K (Kiecolt et al., 198 5 ; O ' Lea ry, 1990 ). N K Ya n g (20 00 ) 0 CD CD8 N K., CD8 N K CD/ CD8 (Ya n g, 200 0 ). N K CD8 T B (Daich u et a l., 1999 ), CD8 N K, B h/ s. B CD 19. Br ewit t (19 97 ) (War dell, 2 00 1 ), Reik i t ou ch 3 0 Ig A (Wa r dell, 2 00 1). CD3 1, CD32, CD33 CD3 (MCD ). CD3 3 m yeloid, CD3 (Kwon et a l, 19 98 ),. B CD 19. CD h/ s, CD8 N K..,. 200 1 7 10 3 5 ( 3 1, 2 3 ). Ca rt er r eflexology Ch ia Ch i- m a ssa ge (2 00 1) 10 3 5.,,. SP SS/ P C (10.0 ), Cr onb a ch ' s alph a, ²- t est t - t est, pa ir ed t - t est in dep en den t t -t est.. 1. 1 5 (p =.0 3, p =.00 5), 1 (p =.000 ) 5. 2. (p =.0 0 ). 3. (p =.02 ) (p =.000 ).. B - 7 2 3 -
2 0 0 2 10 (p =.02, p =.0 06 ), CD 19 (p =.0 08 ). T N K.,..,. Re f e re n ce s Appleba u m, J. W. (19 92 ) Th e r ole of t h e im m u n e syst em in t h e p at h ogen esis of ca n cer. On col N u rs, 8 (1) ; 5 1-62. Baik, H. G. (1999 ). T h e effect iv en ess of foot - reflex o-m assage t o p rem en st ru al sy n drom e an d dy sm en orrh ea. U n pu blish ed m a st er ' s t h eses, Dep. of N u r sin g of Seou l N a t ion a l U n i. Kor ea Baldr ee, K. S., Mu r ph y, S. P., & P ow er s, M. J. (1982 ). St r ess iden t ifica t ion a n d copin g pa t t er n in p at ien t s on h em odia lysis. N u rs R es, 3 1 (2 ), 107-112. Birk, T. J., Mcgr a dy, A., Ma ca rt h u r, R. D., & Kh u der, S. (200 0 ). Th e effect s of m a ssa ge t h er a py a lon e a n d in im m u n e syst em m ea su r es a n d qu a lit y of life in h u m a n im m u n odeficien cy viru s, J A lt Com pl M ed, 6 (5), 0 5-1. Byer s Dwigh t, C. (198 ). B et t er H ealt h w it h Foot R eflex ology. In gh a m pu b. co. Cart er, M., Weber, T. (2000 ). Han d R eflex ology. Pr ent ice H a ll. Ca u dell, K.. A.. (199 6 ). P sych on eu r oim m u n ology a n d car e. In n ovat ive beh avior al int ervent ion s in pat ient s wit h leu k em ia. On col N u rs Foru m, Apr. 23 (3 ), 9 3-50 2. Ch oe, C. J., Oh, D. J., Oh, S. Y. (2 000 ). Th e effect s of gu id ed im a gery on orient in g r eflex. S eou l W om en 's College of N u rsing, Vol. 13, 78-8 8 Cor dova, H. R., Ben a be, J. E., & Mar t in ez- Ma ldon a do, M. (199 1). Clin ical m a nifest at ion a n d com plicat ion s of t h e u r em ic st a t e. In H.R. J a cobson, G.E. St rik er & SK Lah r, T h e Prin ciple an d Pract ice of N ep h rology. Ph ila delph ia : W>B. Sau n d er s Com pa n y. Daich ou, Y., Ku r a sh ige, S., H a sh im ot o, S., Su zu k i, S. (199 9 ). Ch a r a ct erist ic cyt ok in e pr odu ct s of Th 1 cells in h em odia lysis pa t ient s. N eph ron, 83 (3 ), 2 37-2 5. Kiecolt, G. R., Gla ser, R. K., Gla ser,. J. K., St ou t, J. C., J ar r, K. L., P eich er, C. E., H olliday, J. E. (198 5 ). St r ess r elat ed Im pairm ent s in Cellu lar Immu nit y. Psy ch iat ry Press, 16, 23 3-239. Kim, K. O. (2 000 ). T h e effect s of foot reflex t o t h e com fort of long t im e st an ding fem ale w ork ers. U n pu blish ed doct or a l dissert a t ion, Dept. of N u r sin g of Pu sa n N a t ion a l U ni. Kor ea. Kwon, M. S., Kwon, H. H., Kim, I. T., P ark, K. H., & Lee, Y. J. (1998 ). Clinical Im m u n ology. Doseoch u lp a n Kor ea - Medicin pu b. Lee, L. A., Hick s, G., N in o- Mu r cia, G. (199 1). Va lidit y a n d Reliabilit y of a sca le t o Assess F a t igu e. Psy ch iat r R es, 3 6, 2 9 1-2 98. Lee, S. H. (200 0 ). Effect s of p ost p ar t u m m a ssa ge pr ogr a m on st r ess r esp on se in t h e Cesar ea n sect ion m ot h er s. J Korean A cad N u rs, 30 (2 ), 88-9 7. Lee, S. Y., Lee, H. J., Hu r, W. S., Kim, D. J., Kim, Y. G., Oh, H. Y., J o, S. K., Ch o, W. Y., Kim, H. K. (200 1). Cognit ive fu n ct ion a n d qu alit y of life in p at ien t s wit h ch r onic r en al fa ilu r e on h em odialysis. Korean J. N eph, Vol. 2 0 (3 ), 27-37. Lim, N. Y., Son g, K. Y., H on g, Y. H., Kim, J. - 7 2 -
3 2 5 I., Kim, K. H, Ch o, N. O., H a n, K. S. (200 0 ). Com p lem ent al A lt ern at ed N u rsing. Soo- m oon- sa pu b. Mit zel- Wilk in son, A. (2 000 ). Ma ssa ge t h er a py a s a nu r sin g pr a ct ice. H olist ic N u rs Pract, 1 (2 ), 8-56. O ' Lea ry, A. (1990 ). St r ess, em ot ion a n d h u m a n im m u n e fu n ct ion. Psy ch ol Bu ll, 108, 3 63-392. Oh, J. J. (2 000 ). Th e effect of h a n d- m a ssa ge on t h e r elaxat ion of dem ent ia pat ient s. J Korean A cad N u rs. 30 ( ), 82 5-83 5. Oh, S. Y. (200 1). T h e effect s of h an d reflex ology on S aen g -ch i an d im m u nit y in ES R D p at ient s. U n pu blish ed doct or a l dissert at ion, Dept. of N u r sin g of H a n ya n g U n i. Kor ea. P a rk, M. S., Su h, M. J. (19 9 5). Th e effect of t h e h a n d m a ssa ge on a n xiet y of t h e ca n cer pa t ient s r eceivin g r a dia t ion t r ea t m ent. J Korean A cad N u rs, 2 5 (2 ), 3 16-329. Ra n dolph, G. L. (198 ). Th er a p eu t ic a n d ph ysica l t ou ch : P h ysiologica l r espon se t o st r essfu l st im u li. N u rs R es, 33 (1), 33-36. Ra sk ova, J., Gh bria l, I., Sh ea, S., E Isin ger, R. P., Ra sk a, K. (198 ). Su p pr essor cells in En d- St a ge r en al disea se, fu n ct ion a l a ssa ys a n d m on oclon al a nt ibody a n alysis. A m J M ed, 76, 8 7-8 53. Sh ik e, M. (19 96 ). N u t rit ion t h er a py for t h e ca n cer pa t ient. H em at ol On col Clin N ort h A m, 10 (1), 22 1-23. Snyder, M., & Lin d qu ist, R. (1998 ). Com ple - m ent ary A lt ern at iv e. T h erapies in N u rsin g. 3r d E d. sprin ger Pu b. 63-7. Tonin i, G., Nu n zia t a, C., Pr et e, S. P., P epponi, R., Tu rrizia n i, M., Ma sci, G., Gr a ziat a, G., Bonm a ssa r, E., Vecch is, L. (19 98 ). Aj u va nt t r ea t m en t of br ea st ca n cer : a pilot im m u n och em ot h er a py sru dy wit h CMF, int erleu kin- 2 a n d int erfer on-. Can cer Im m u n ol Im m u n ot h er, 7 (3 ), 157-166. War dell, D. W. (200 1). Biologica l corr ela t es of Reiki t ou ch h ea lin g. J A dv N u rs, 33 ( ), 39-5. Ya n g, C. H. (2 000 ). T h e effect s of m ent al st ress lev els an d recreat ion al ex ercise on im m u n e fu n ct ion an d ant iox idan t en zy m e act iv it ies. U n pu blish ed doct or a l disser t a t ion, Kor ea n N at ion al U ni. of Ph ysica l E du ca t ion. Ya n g, Y. H., Kwon, S. J., Kim, C. I. (2 00 1). Th e nu t rit ion al st a t u s of t h e pa t ient s wit h ca n cer du r in g t h e ch em ot h er a pies. J A cad N u rs, 3 1 (6 ), 978-9 87. - Ab s t r a c t - Korean Effe ct s of Ha n d Reflex ology on Ph y s iologica l Em ot ion a l Re s p on s e s a n d Im m u n it y in t h e Pa t ien t s wit h Ch r on ic illn es s ; Ch r on ic r en a l fa ilu r e p a t ien t s a n d Ca n cer p a t ien t s Le e, Ch u n g -He e * Oh, S ei -Y ou n g ** Park, Ok -S oon ** Kw on, In -Gak *** J e on g, Mi -A *** Le e, Eu n -A *** P u r p o s e : Th e pu r p ose of t h is st u dy wa s t o explor e t h e effect s of h a n d r eflexology on t h e ph ysiological em ot iona l r espon ses a n d imm u nit y of t h e p at ien t s wit h ch r on ic illn ess. Th is st u dy look ed specifically a t p at ien t s wit h ch r onic r en a l failu r e (CRF ) a n d ca n cer pat ient s. Me t h o d : Th is st u dy wa s design ed a s a qu a si- exp er im en t al n on equ iva lent cont r ol gr ou p pr e a n d post t est. Su bj ect s wer e 5 pa t ient s wh o r eceived dia lysis a n d ch em ot h er a py in on e h ospit al. Th ir t y- on e p at ient s w er e a ssign ed t o t h e exp er im en t al gr ou p a n d 2 3 t o t h e cont r ol gr ou p. Th e h a n d r eflexology w a s a pplied t o b ot h h a n ds of t h e experim ent gr ou p for t en * Su n gk yu n k w a n U n iv er sit y ** Seoul Wom en ' s College of Nur sin g *** S a m su n g M e di ca l C en t er - 7 2 5 -
2 0 0 2 10 m inu t es ea ch t im e, 5 t im es du r in g t h r ee d ays. F or da t a collect ion, ph ysiologica l la b levels, im m u n e cells of blood a n d qu est ion n a ir es for em ot ion a l r espon ses wer e m ea su r ed befor e a n d a ft er t h e pr ogr a m. Re s u l t : BT of t h e experim ent gr ou p w a s decr ea sed significa nt ly on bot h of t h e 1st a n d t h e 5t h a p plicat ion. P R & BP w er e decr ea sed significa nt ly on t h e 1st t im es, bu t n ot 5t h t im es. Hb levels of t h e experim ent a l gr ou p wer e significa nt ly in cr ea sed. An d em ot ion a l r espon ses, vigor a n d m ood scor es of t h e experim ent gr ou p wer e significa nt ly in cr ea sed. B cell & CD 19 wer e in cr ea sed significa nt ly on t h e experim ent gr ou p. Su p pr essor T cell a n d N K cell sh ow ed significa nt decr ea se aft er t h e pr ogr am, bu t n o significa nt differ en ces b et ween t h e gr ou ps. Co n c lu s i o n : We h ave fou n d t h a t t h e h a n d r eflexology h elps t h e ch r onic pat ient s t o im pr ove ph ysiological em ot ion a l r esp on ses a n d t h e im mu n e r ea ct ion. Th r ou gh t h is r esu lt, t h e h a n d r eflexology is effect ive a s a int er ven t ion of p sych on eu r oimm u n ologic fu n ct ion. Ke y w o rd s : H a n d r eflexology, Ph ysiologica l em ot ion a l r esp on ses, Im m u nit y - 7 2 6 -