- 1 -
,,,,,,,, (), BOD,,,,,,,,, - 2 - - 3 -
3) 4) 5) 6) 7) - 4 - - 5 -
(Analytical Spectrum) 1 Biosensors 2 Electro Analysis 3 Environmental 4 Drug Discovery 5 Food Quality and Safety 6 Gas and Liquid-phase Chemical Sensors 7 Life Sciences Research - 6 - - 7 -
10) 11) - 8 - - 9 -
12) 13) - 10 - - 11 -
14) 15) - 12 - - 13 -
⑴ Automation-robotics, cloning, DNA and RNA purification, electrophoresis, food and GMO testing, genotype analysis, in-vitro Genomics transcription, microarrays, PCR, plant biotechnology, reverse transcription and DNA synthesis, RNA interference, and sequencing Electrophoresis, gene expression and reporter assays, mutagenesis, Proteomics protein interactions, protein expression and analysis, RNA interference, and transfection Genetic identity Genetic identity analysis Apoptosis, automation-robotics, cell viability, drug discovery, gene Cellular expression and reporter assays, Immunological detection, In vitro analysis toxicology, signal transduction (including neuroscience), transfection 2003 2004 2005 2006 2007 2008 2009 2012 2016 CAGR Res Lab 470 503 541 585 636 696 756 1,006 1,539 9.6% POC 1,803 2,005 2,230 2,439 2,679 2,945 3,218 4,259 6,470 10.3% HM Diag 777 836 903 980 1,069 1,174 1,290 1,790 2,919 10.7% Process 296 314 335 359 386 418 456 606 951 9.4% Env. 472 515 565 622 659 757 831 1,209 2,065 12.0% Security 87 97 108 121 136 153 173 258 477 14.0% 3,905 4,270 4,682 5,106 5,595 6,143 6,723 9,128 14,421 10.6% - 14 - - 15 -
2003 2005 2007 2009 BioAgent Detector 64.3 75.2 89.7 109.5 Bioreporter 62.4 73.0 87.1 106.4 Multi-analyte Sensing 82.2 95.8 113.9 138.6 Flow Immunosensor 67.6 75.8 86.5 101.0 Optical Fiber and Fluoroimmunoassay 81.2 92.5 107.5 127.8 Medical Telesensors 68.1 77.4 89.7 106.4 Anthropometry 43.7 51.4 61.7 75.8 2006 2009 LifeSensors 25.0% 16.0% Biocore 19.0% 10.0% 2006 6 GE 3.9 Affinity Sensors 10.0% Thermo Scientific LifeScan, Inc 16.0% 10.0% Oxford Biosensors 6.0% NASA 5.0% Sensortec Limited(universal Sensors Ltd) 4.0% Ibis BioSciences 4.0% Axela Biosensors 4.0% Honda Trading Co; (Tokyo, Japan) 5.0% 3.0% Biosensor Research Institute of America 3.0% Chiron 2.0% 2.0% - 67.0% 77.0% ⑵ 2003 2005 2007 2009 Glucose 518.0 678.1 799.4 951.8 Cardiac biomarkers 235.3 306.5 398.6 513.2 Infectious diseases 198.0 263.2 346.5 451.3 Coagulation PT 147.5 190.5 244.9 315.5 Pregnancy 197.6 207.2 218.5 231.5 Coagulation ACT 119.2 138.3 159.1 185.3 Cholesterol 95.8 115.2 138.3 167.4 Hematology 145.6 157.9 168.5 185.3 AIC 57.2 77.6 102.2 134.6 Drugs of abuse 88.7 95.4 103.3 111.9-16 - - 17 -
2006 2009 Roche Diagnostic 16.0% 15.0% Abbott 14.0% 13.0% LifeScan, Inc 13.0% 12.0% Bayer 12.0% 11.0% MediSense 10.0% 9.0% Axela Biosensors, Inc 5.0% Advanced Biosensor Inc 5.0% M-Biotech, Inc; 3.0% Ibis BioSciences, Inc. 2.0% 65.0% 75.0% ⑶ 2003 2005 2007 2009 Glucose Meters 620.1 718.8 848.8 1028.1 Coagulation Meters 62.2 74.1 89.8 111.6 Cholesterol Meters 48.2 57.8 70.6 88.3 Other Testing Meters 46.6 52.4 59.9 70.1 2006 2009 LifeScan, Inc 20.0% 18.0% Roche Diagnostic 18.0% 16.0% Abbott 10.0% 10.0% - Bayer 8.0% 8.0% - MediSense 5.0% 5.0% - Oxford Biosensors Ltd 3.0% 3.0% - Ibis BioSciences, Inc. 3.0% Axela Biosensors, Inc 3.0% 64.0% 66.0% - 18 - - 19 -
⑷ 방법은 전류측정 전위차 으로분류 2003 2005 2007 2009 Alcohol 100.6 112.6 127.8 149.6 Glucose 64.8 72.7 82.6 96.7 Lactic Acid 53.0 60.6 70.3 83.4 Peptide 27.5 31.8 37.1 44.7 E.coli 0157 18.9 21.1 24.3 28.7 Salmonella 11.2 13.1 15.4 18.2 Listeria 6.2 7.4 8.9 10.9 2006 2009 Universal Sensors 13.0% 13.0% - Affinity Sensors 12.0% 12.0% - Yellow Springs 11.0% 11.0% - Sensortec Limited(Universal Sensor) 10.0% NASA 7.0% 36.0% 53.0% ⑸ - 20 - - 21 -
2003 2005 2007 2009 Toxicity 292.4 356.7 445.2 557.8 BOD Ecoli/Coliform 134.9 155.9 182.3 221.9 Crypto 13.3 15.3 18.0 21.5 Girdia 13.3 15.3 17.7 21.5 MicroCystins 18.5 21.5 25.4 17.5 2006 2009 Strategic Diagnostics(AZUR) 16.0% 16.0% - Waste Technologies of Australia Pty.Ltd 13.0% 13.0% - Remedios 12.0% 12.0% - Sensortec Limited(Universal Sensors) 8.0% Bruno Lange & Hach Lange 8.0% 8.0% - 49.0% 57.0% ⑹ West Nile, SARS(Severe Acute Respiratory Syndrome), Anthrax Biological detection E.Coli 0157:H7, BSE(Bovine Spongiform Encephalopathy) Drug and narcotic Cocaine, Meth-amphetamines, Ecstasy, Opiates detection THC(cannabis)(Tetrahydrocannabinol) TNT explosives(tri-nitrotoluene), Tetryl, Nitroglycerin Chemical and explosive DNT(Di-nitrotoluene or Dinitro) substance detection RDX(Cyclo tri-methylene tri-nitramine-cyclonite, hexogen, and T4) PETN(Pentaerythritol Tetranitrate) - 22 - - 23 -
2003 2005 2007 2009 West Nile 11.7 14.1 17.3 21.7 SARS 11.5 13.9 17.0 21.3 E.coli 0157 10.8 13.2 16.3 20.6 BSE 9.8 12.0 14.8 18.7 Anthrax 4.8 6.1 7.8 10.2 Cocaine 4.2 5.4 6.9 9.1 Metha-Phetam 2.8 3.2 3.6 4.2 Ecstasy 3.7 4.7 6.0 7.9 Opiates 2.5 3.2 4.2 5.6 THC cannabis 1.3 1.7 2.4 3.3 TNT explosives 3.9 4.7 5.7 7.1 Tetryl 1.4 1.9 2.5 3.5 DNT 1.9 2.5 3.3 4.4 RDX 4.5 5.5 6.6 8.3 Nitro-glycerin 0.9 1.3 1.9 2.7 PETN 0.8 1.1 1.5 2.2 32) 전게서 2006 2009 Toray Imdustries(America), Inc. 12.0% 11.0% Gen-Probe 11.0% 10.0% InPro 10.0% 9.0% Prionics 10.0% 9.0% NASA 7.0% Innovative Biosensors 6.0% Biosensor Applications Sweden AB. 6.0% BioRad 8.0% 5.0% ExmovereLLC(ExmovereHoldings) 5.0% 51.0% 68.0% 06 09 16 Research Drug Discovery 3.0% 3.3% 3.6% Laboratories Rest of Research 8.4% 8.5% 8.0% Cholesterol 1.2% 1.4% 1.5% Home Diagnostics Coagulation() 1.6% 1.7% 1.9% Glucose* 31.2% 31.6% 30.3% 1.1% 1.5% 1.4% Cholesterol 2.5% 2.0% 1.9% Cardiac Biomarkers 6.8% 7.5% 8.6% Infectious Diseases 5.9% 5.8% 7.3% Pregnancy 4.2% 3.6% 1.9% POC Drugs of Abuse 1.9% 1.7% 0.9% Coagulation PT 4.2% 4.6% 5.2% Coagulation ACT 2.9% 2.6% 2.3% Hematology 3.2% 2.8% 1.8% A1C 1.7% 0.9% 1.2% Alcohol 2.3% 2.3% 2.1% Lactic acid 1.3% 1.3% 1.2% Process Industries Peptides 0.7% 0.7% 0.7% E.coli 0157:H7 0.4% 0.4% 0.3% Salmonella 0.3% 0.3% 0.3% Listeria 0.2% 0.2% 0.2% Toxicity 7.8% 8.8% 10.6% Ecoli/Coliform 3.3% 3.3% 2.9% Env. Monitoring Crypto 0.3% 0.3% 0.3% Girdia 0.3% 0.3% 0.3% Micro Cystins 0.5% 0.5% 0.5% West Nile Virus 0.3% 0.3% 0.4% SARS 0.3% 0.3% 0.4% E.coli 0157:H7 0.3% 0.3% 0.4% Biological Detection BSE (Bovine Spongiform Encephalopathy) 0.3% 0.3% 0.3% Anthrax 0.1% 0.2% 0.2% Cocaine 0.1% 0.1% 0.2% Drug and Narcotic Meth-amphetamines 0.1% 0.1% 0.1% Security & Ecstasy 0.1% 0.1% 0.2% Detection Bio defense Opiates 0.1% 0.1% 0.1% THC (cannabis) 0.0% 0.1% 0.1% TNT Explosives 0.1% 0.1% 0.1% Tetryl 0.0% 0.1% 0.1% DNT 0.1% 0.1% 0.1% Explosive Detection RDX 0.1% 0.1% 0.2% Nitroglycerin 0.0% 0.04% 0.06% PETN(Pentaerythritol Tetratrate) 0.03% 0.03% 0.05% ( ) 51.1 67.2 144.2-24 - - 25 -
: : Vol.5, No.10 2011 기계기술정책 KIMM Technology Policy 발행처 한국기계연구원정책연구실 발행일 2011. 10 기획 편집 곽기호, 박효주, 박준식 ( 자연모사연구실 ), 석호준 ( 한국생명공학연구원 ) 김재윤, 오승훈, 정준호 주소 대전광역시유성구가정북로 156번지 전화 (042) 868-7682 ( 정책연구실 ) 35) (2002), - 26 - - 27 -