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1 Aug 2011 Volume 31 No.8 발행인 : 이혜숙 편집위원 : 정선회, 조윤희, 백진희, 박향미, 남유경, 최정윤, 사은영, 박미정, 김선지, 구은해, 이정란, 이소영 서울특별시종로구대학로 101 전화 :(02) CONTENT 약사위원회소식 1 약제부에서 7 FDA 승인약물 2 약제부소식 8 특집 : 분할 분쇄해서조제하지않는의약품 4 약사위원회소식 Pharmacy & Therapeutics Committee 지난 2011 년 6 월약사위원회 ( 6. 24) 에서새로사용하기로결정된약품들과기타결정사항을알려드립니다. 그리고아래의약품이구매되어사용되기까지는다소시간이소요됨을알려드립니다. 1) 신규사용하기로결정된약품목록 상품명 ( 약품명, 생산사 ) 함량, 제형 효능, Clipper gastro-resistant modified release tab (Beclomethasone dipropionate 5mg tab Chiesi, Italy( 판매원 : 코오롱제약 )) Votrient tab (Pazopanib HCl 200mg tab Glaxo Group, UK( 판매원 : 글락소스미스클라인 )) Votrient tab (Pazopanib HCl 400mg tab Glaxo Group, UK( 판매원 : 글락소스미스클라인 )) 5mg gastroresistant MR tab 200mg tab 400mg tab 경증또는중등증의활동성궤양성대장염의치료 항악성종양제 2) 규격, 제형, 용기추가및대체약품목록 상품명 ( 약품명, 생산사 ) 함량, 제형효능, Diamicron MR tab (Gliclazide 60mg tab Les Laboratories ervier, France ( 판매원 : 한국세르비에 )) 60mg MR tab 당뇨병용제 Meropenem 1g inj 1g vial 항생제, 사용개시일미정 Mirapex ER tab (Pramipexole dihydrochloride 0.375mg tab - Boehringer Ingelheim, Germany( 판매원 : 삼일제약 )) 0.375mg ER tab Mirapex ER tab (Pramipexole dihydrochloride 0.75mg tab - Boehringer Ingelheim, Germany( 판매원 : 삼일제약 )) 0.75mg ER tab 항파킨슨제 Mirapex ER tab (Pramipexole dihydrochloride 1.5mg tab - Boehringer Ingelheim, Germany( 판매원 : 삼일제약 )) 1.5mg ER tab piriva Respimat inhaler (Tiotropium Bromide monohydrate 2.5mcg inhaler - Boehringer Ingelheim, Germany( 판매원 : 한국베링거인겔하임 / 한국화이자 )) Tropherine ophthalmic solution (0.5% Tropicamide / Phenylephrine HCl 0.8ml amp - 한미약품 ) Paracaine ophthalmic solution (0.5% Proparacaine HCl 0.8ml amp - 한미약품 ) 2.5mcg inhaler 0.5% (0.8ml x 30)/box 5% (0.8ml x 30)/box 호흡기관용제 ( 기관지확장제 ) 산동제 (TPCPE 대체 ) 안과용국소마취제 (PPRC 대체 ) Charcotrace inj (Activated Charcoal 120mg/3ml vial Phebra Pty Ltd, Australia( 판매원 : 헤라팜 )) 120mg/3ml vial 수술보조제 Andilac- powder (Lactobacillus acidophillus 300mg(1억개 )/g, 200g/btl 일양 ) 300mg/g, pow 정장제 3) 원외등록약목록 상품명 ( 약품명, 생산사 ) 함량, 제형효능, Amosartan 10/50 tab (Amlodipine 10mg(-camsylate) / Losartan Potassium 50mg tab 한미 ) Cozaar XQ 10/50 tab (Amlodipine Camsylate 15.68mg / Losartan Potassium 50mg tab 한국엠에스디 ( 위탁제조 : 한미 )) DicaMax500 Chewable tab (CaCO 3 1,875mg(Ca 750mg) / Cholecalciferol 500 IU tab - 다림바이오텍 ) 10mg/50mg tab 1,875mg(Ca 750mg) / 500IU tab 혈압강하제 Ca / vit D 복합제

2 상품명 ( 약품명, 생산사 ) 함량, 제형효능, DicaMax D tab (CaCO 3 250mg(Ca mg) / Cholecalciferol 1,000 IU tab - 다림바이오텍 ) 250mg(Ca mg) / 1,000IU tab Vit D 보급제 4) 생산및수입중단관련변경사항 상품명 ( 약품명, 생산사 ) Betadine soln (Povidon iodine 10% 1,000ml btl 현대약품 ) 현대약품선정삭제 Betadine scrup (Povidon iodine soap 7.5%, 3,785ml(1GL) btl 현대약품 ) 현대약품선정삭제 Minecin tab (Prazosin 1mg tab 세종제약 ) 구매중지 Picibanil 1KE inj (treptococcus pyrogens(a군 3형 ) u주건조균체 0.1mg vial - CHUGAI(F6)( 판매원 : 중외제약 )) 구매중지 Ecolicin oph.soln (Erythromycin lactobionate 5mg/Colistin sodium methanesulfonate 5mg/ml, 5ml btl - ANTEN(F6)( 판매원 : 태준제약 )) 구매중지 fenal inj (Alfentanil HCl 1mg/2ml amp 비씨월드제약 ) 비씨월드제약선정삭제 5) 제조원, 수입 / 판매원변경관련사항상품명 ( 약품명, 생산사 ) Megace susp (Megestrol 40mg/ml, 240ml btl B.M.QUIBB(F6)( 판매원 : 보령제약 )) 제조원변경 (B.M.QUIBB(F6) 보령제약) Leunase inj (Asparaginase(L-) 10,000 IU vial KOWA(F6)( 판매원 : 제일기린 )) 수입 / 판매원변경 ( 중외제약 제일기린 ) Mitomycin-c Kyowa inj (Mitomycin 10mg vial - KOWA(F6)( 판매원 : 제일기린 )) 6) 일부스테로이드호르몬제의 1 일 1 회 default 용법변경 약품명 Prednisolone 5mg tab Dexamethasone 0.5mg tab 아침 7시 아침식후 30분아침식전 30분 아침식후 30분 7) 기타사항 내용 마약류관리지침개정 2011 년종합병원마약류관리지침발표 ( 식품의약품안전청 ), Propofol 의향정신성의약품지정확정및공포 (2/1, 식품의약품안전청 ), 병원내조직개편 ( 암진료조제파트신설 ) 에따른개정 (7/1 일자시행 ) FDA 승인약물 FDA Approved Drug Products 성분명 ( 상품명 ) Linagliptin (Tradjenta ) Boceprevir (Victrelis ) 함량제형적응증제약회사 FDA 승인일 5mg 200mg Capsule Dipeptidyl peptidase-4 (DPP-4) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus Hepatitis C virus N3/4A protease inhibitor for the treatment of chronic hepatitis C genotype 1 infection, in combination with peginterferon alfa and ribavirin, in adult patients ( 18 years of age) with compensated liver disease, including cirrhosis, who are previously untreated or who have failed previous interferon and ribavirin therapy Boehringer Ingelheim chering *Review classification molecular entity () P

3 성분명 ( 상품명 ) Rilpivirine hydrochloride (Edurant ) Telaprevir (Incivek ) Fidaxomicin (Dificid ) Hydrocodone; chlorpheniramine; pseudoephedrine (Zutripro ) Hydrocodone; pseudoephedrine (Rezira ) Ezogabine (Potiga ) Phentermine hydrochloride (uprenza ) Nitroglycerin (Rectiv ) Morphine sulfate (Morphine sulfate ) Levothyroxine sodium (Levothyroxine sodium ) Fentanyl citrate (Lazanda ) 함량제형적응증제약회사 FDA 승인일 EQ 25mg base 375mg 200mg 5mg; 4mg; 60mg 5mg; 60mg 50, 200, 300, 400mg 15, 30mg 0.4% 20mg/ml, 200, 500mcg, 400mcg olution; oral olution; oral In combination with other antiretroviral agents for the treatment of HIV-1 infection in treatment-naïve adult patients Hepatitis C virus N3/4A protease inhibitor in combination with peginterferon alfa and ribavirin, for the treatment of genotype 1 chronic hepatitis C in adult patients with compensated liver disease, including cirrhosis Macrolide antibacterial drug indicated in adults ( 18 years of age) for treatment of Clostridium difficile-associated diarrhea Antitussive, an antihistamine, and a nasal decongestant indicated for Relief of cough and nasal congestion associated with common cold Relief of symptoms including nasal congestion associated with upper respiratory allergies Antitussive and nasal decongestant indicated for Relief of cough and nasal congestion associated with common cold Potassium channel opener indicated as adjunctive treatment of partial-onset seizures in patients aged 18 years and older A sympathomimetic amine anorectic indicated as a Orally short-term adjunct in a regimen of weight disintegrati reduction based on exercise, behavioral ng tablet modification and caloric restriction in the management of exogenous obesity Ointment; intra-anal olution; oral Nitrate vasodilator indicated for the treatment of moderate to severe pain associated with chronic anal fissure Management of moderate to severe acute and chronic pain in opioid-tolerant patients Powder; IV Treatment of myxedema coma pray, metered; nasal Opioid analgesic indicated only for the management of breakthrough pain in cancer patients, 18 years of age and older, who are already receiving and who are tolerant to opioid therapy for their underlying persistent cancer pain Tibotec Vertex Pharms Optimer Pharms Cypress Pharm Cypress Pharm Valeant Pharma Citius Pharma Prostrakan Inc Lannett App Pharms Archimede s *Review classification combination combination formulation formulation formulation Drug already marketed, but without an approved NDA formulation P P * Review Classification Letter Meaning P Priority review drug: A drug that appears to represent an advance over available therapy tandard review drug: A drug that appears to have therapeutic qualities similar to those of an already marketed drug 0 Orphan drug References 입원조제파트사은영

4 특집 처방 조제시주의를요하는약품 분할 분쇄해서조제하지않는의약품 원내에서처방가능한경구용의약품중에서약제학적특징으로분할 분쇄해서조제하지않는의약품의대체가능한제형및 EMR 처방 여부를함께알려드립니다. < 표설명 > 약품명의윗첨자 : 동일성분의대체가능한제형 plain or dispersible tab/cap powder c) sprinkle cap EMR : 대체가능한의약품의 list 를제시하여그중에한제형을선택할수있음 1. 서방정제제 1~63: 서방형정제 64: 서방 장용정 65~77: ORO(Osmotic-controlled Release Oral delivery ystem) 서방형제제 1 AAP6 Acetaminophen Tylenol ER AFZ10 Alfuzosin Jexatron XL, Xatral XL 10 3 BPPO Bupropion HCl Wellbutrin R BPPO Bupropion HCl Wellbutrin XL 5 BPPO BZF4 Bezafibrate Bezalip retard CBM2 Tegretol CR 8 CBM2M Carbamazepine Carmazepine 200 CR 9 CRTM5 Clarithromycin Klaricid XL DTA9 Diltiazem Herben retard DVPA2 250 Divalproex Na c) Depakote ER 12 DVPA ETDL6 Etodolac micronized Lodine R FLDP2 2.5 Felodipine Munobal 15 FLDP 5 16 FRB Dried Ferrous sulfate Feroba you FTR4 4 Fesoterodine Toviaz 18 FTR FV80 Fluvastatin Lescol XL GCZ30 Gliclazide Diamicron MR IDP15 Indapamide Natrix R IBD40 Isosorbide Isoket retard IBD40K dinitrate Angibid IBM6 Isosorbide-5- mononitrate Elantan R KCL KCL K-contin KCT10 27 LC Potassium citrate Urocitra K R 1080 Levodopa + carbidopa inemet CR MLZ5 Mesalazine Pentasa R MTF5 Metformin HCl Metophage XR, Novamet GR MTFGM2 Metformin / Glimepiride Amaryl-Mex 2/ MTP95 Metoprolol succinate Prolol ER NCTA5 Nicotinic acid Exlip ER NCTA1LP2 Nicotinic acid ER/Laropiprant Tredaptive 0/ ND10 10 Nisoldipine yscor ER 35 ND OCD OCD20 Oxycodone 20 Oxycontin CR 38 OCD OCD PCTF160 Procetofen Lipidil upra PTX Pentoxifylline Perental R, Trental R QTP QTP2 Quetiapine 200 eroquel XR 44 QTP QTP RPN RPN4 Ropinirole Requip PD 4 48 RPN V2 imvastatin imvast CR TMTZ3 Trimetazidine Vastinan MR TOP2QD 200 Theophylline Uniphyl R 52 TOP4QD TRM Kontram XL, 150 Tramadol Zytram XL Tramaconti CR, 54 TRM2 Zytram XL TRM7AAP6 Tramadol/AAP Ultracet ER 75/ VPA VPA Valproic acid Orfil R VPA VPAV3 Depakine 300 Valproic acid 60 VPA5 chrono VRP18 Verapamil Isoptin R ZPD6 Zolpidem Tartrate tilnox CR ZPD POXT1 Paroxetine Paxil CR 12.5

5 Doxazon XL, 4 65 DXZ4 Doxazosin Cadura XL, Pzocin XL 66 HMP8 8 Hydromorphone Jurnista 67 HMP16 Prolonged HMP32 release MPND18 Methylphenidate Concerta ORO MPND NFD3 30 Nifedipine Adalat ORO 72 NFD OBT5 Oxybutynin 5 Lyrinel ORO 74 OBT PLP PLP6 Paliperidone Invega ER 6 77 PLP 서방캡슐제제 1~21: 서방효과를가진과립을충진한캡슐 22~26: 서방및속방과립함유캡슐 27: HB(Hydrodynamically Balanced ystem) 제제 1 CBP15 15 Cyclobenzaprine Bonelax ER 2 CBP DDI2 250 Didanosine Videx EC 4 DDI DTA18 Diltiazem Herben R GLTM8C 8 7 GLTM16C Galantamine Reminyl PRC 16 8 GLTM24C 24 9 IBD Isosorbide Isoket retard IBDK dinitrate Angibid IRDP5 Isradipine Dynacirc RO 5 12 NCD4 Nicardipine Perdipine LA BT4 4 albutamol albutron R 14 BT TOP1 Etheophyl 16 TOP2 Theophylline TOP13 Theoclear TL Tamsulosin Tamsulosin, Tamunal VLF3X 37.5 Venlafaxine Effexor XR 20 VLF7X VPA3C odium Valproate Orfil long retard BND 5 Barnidipine Oldeca 23 BND MPND10 Methylphenidate HCl Metadate CD MPND RNEB Ebastine/ pseudoephedrine Rinoebastel 10/ LB Levodopa /benserazide Madopar HB /25 3. 장용정 / 장용캡슐 / 장용과립제제 1~19: 장용정 20~21: 장용과립 22~23: 제피세립정 24~31: 장용과립을충진한캡슐 1 ACPT Acamprosate Acamprol enteric coated AAT1 Aspirin Aspirin protect 3 BC Bisacodyl Bisacodyl 5 4 ETR150 Vitis vinifera extract Entelon ILPZ Ilaprazole Noltec 10 6 KLN5 Kallidinogenase Carnaculin 50IU 7 MPN1 Mycophenolate Myfortic enteric MPN3 sodium coated MLZ Mesalazine Mesalazine MLZ4 Mesalazine Asacol DR OMP1 10 Omeprazole Omed 12 OMP PTP20 20 Pantoprazole Pantoloc 14 PTP RBPZ10 10 Rabeprazole Rabekan 16 RBPZ OMP2 Esomeprazole 20 Nexium 18 OMP4 magnesium LZ ulfasalazine Zopyrin enteric alazopyrin EN ALX8 Plantago seed 외 2종 Alaxyl granule 21 TUE Tegafur/uracil UFT-E / AAM1 Aspirin Rhonal 23 AAM5 (microcoated) AAE Aspirin Astrix 25 DLXT30 30 Duloxetine Cymbalta 26 DLXT EM Erythromycin Eryc LP15 Lansoprazole 15 Lanston 29 LP OMPT2 Esomeprazole OMPT4 strontium Esomezole tetrahydrate 흡습성제제 1 AMXCV Amoxicillin: Cramotin, Kmoxilin, 375 Clavulanate = 2:1 Augmentin,Moxicle 2 AMXCV6 3 AMXCVD ucla, Kmoxilin, Amoxicillin: Clavulanate = 4:1 Maxiclan, Augmentin Amoxicillin: Clavulanate = 7:1 Amocla Duo, Amoxicle CDTR Cefditoren Meiact 5 CTCL5 Citicoline omazina EMB Ethambutol Tambutol GMFX3 Gemifloxacin Factive LCNT3 L-carnitine L-Carn MZRB2 25 Mizoribine Bredinin 10 MZRB OZP OZP5 Olanzapine Zyprexa 5 13 OZP RVP2 Revaprazan Revanex VLM8 evelamer Renagel TMT40 40 Telmisartan Pritor 17 TMT80 80

6 5. 최기형성이있는약품 1 TLD Thalidomide 6. 식도염부작용이있는약품 Thalidomide Celgene Alend, Marvil 1 ADNT Fosamax ADNT5 Alendronate Marvil 5 Allenmax, Fosa 3 ADNT7 max, Fosaquee 70 n, Alendronate 4 ADNT7CC5 Alendronate / Cholecalciferol Fosamax plus D 70 / 5600IU 5 ADNTCCT Alendronate / Calcitriol Maxmarvil 5 / 0.5mcg 6 ETDR Etidronate Dinol IDNT150 Ibandronate Bonviva RDR5 5 9 RDR35 Actonel 35 Risedronate 10 RDR RDR75 Optinate RDR35CC5 Risedronate / Cholecalciferol Risenex Plus 35 / 5600IU * 식도를거치지않고바로위로통과하는 tube 를가진환자는분쇄후복용가능 7. 연질캡슐제제 1 ACCC Alfacalcidol Alfarol, Alfabon 0.5mcg 2 ACF1C Aceclofenac Clanza 3 APDC Pamidronate Panorin 4 ATRA Tretinoin Vesanoid 10 5 CCTO Calcitriol Calcio, Bonky 0.25mcg 6 CLAP Cholin alphoscer Alfoatoron, Gliatilin CR25 25 Cipol-N 8 CR Cyclosporin 9 CRA2M 25 andimmun 10 CRA1M 11 DT05 Dutasteride Avodart E1 Tocopherol Auropherol 13 E4 Vit E Hanobac 400IU 14 EX Ethosuximide Zarontin GLA4 G-linolenic acid Evoprim GLMTL3 Gelomyrtol Gelomyrtol GP Galspa Galspa 18 ITT Isotretinoin Isotinon, Aknal, Roaccutane, 10 Accunetan 19 MNTT Menatetrenone Glakay NETT Acitretin Neotigasone NFD5 Nifedipine Adalat 5 22 NETT Acitretin Neotigasone OMEGA1 Omacor Omacor 0 24 PG Progesterone Utrogestan 25 RWC Rowachol Rowachol 26 UDX25 ulodexide Vessel due F TAGENF Vaccinium myrtillus Tagen F, Qretin, Anthocyan 28 TR Testosterone Andriol testo 구강붕해정 / 박칼정 / 설하정 / 트로키정 / 확산정 / 현탁정제제 1~15: 구강붕해정 16~18: 박칼정 ( 구강정 ) 19~21: 설하정 22: 트로키정 23~27: 확산정 28: 현탁정 1 BPTD7 Bepotastine Potastin OD DNPZD5 Aricept evess, 5 Donepezil Aldigm OD, 3 DNPZD10 Domentac OD, 10 Donezil OD 4 FMTDD Famotidine Gaster dispersible 20 5 LPL3 Lanston LFDT 6 MZPT3 Mirtazapine Remeron soltab 30 7 ODZ4 Ondansetron 4 Zofran zydis 8 ODZ8 8 9 OZPD5 5 Olazapine Zyprexa zydis 10 OZPD RM Ramosetron Nasea OD RPD RPD1 Risperidone Risperdal quicklet 1 14 RPD TLT Harnal D 16 FTN FTN4 Fentanyl Actiq FTN NG Nitroglycerin Nitroglycerin LAII Purified House 300AU 21 LAIM Dust Mite Allergen Extract LAI 0AU 22 NCT1TRO Nicotine Nicotinell Lozenge 1 23 DFR DFR2 Deferasirox Exjade DFR FOX20D Fluoxetin Prozac dispersible LBD Levodopa / benserazide Madopar dispersable / RXM5D Roxithromycin Rulid-D 분쇄불가는아니지만동일성분가루약 ( 과립, 캡슐 ) 이있는제제 1 ADLC Andilac Andilac ALCNT Acetyl L-carnitine Nicetile, Carnitil, Neurocarn 3 CACB Ca.carbonate Cicibon, CaCO3 united 4 CDNC Cefdinir Omnicef, Anycef 5 CFIX Cefixime uprax, Pocef, Cefix HCO3T odium Tasna 500 bicarbonate Rifodex, 7 RFP6 Rifampicin Rifampin 600 의약정보파트이소영

7 약제부에서 Pharmacy Department Announcement 1) 신약 NO 약품 CODE 성분명제품명규격및제형사용개시일 1 ADLP Lactobacillus acidophillus 앤디락에스산 300mg/g, pow 7월 5일 2 EX Ethosuximide 자론틴캡슐 250mg soft cap 7월 8일 3 LAII 4 LAIM Purified House Dust Mite Allergen Extract_initial Purified House Dust Mite Allergen Extract_maintenance 라이스정 라이스정 300AU/tab, 10T/box 1,000AU/tab, 10T/set, 30tab/box 7 월 11 일 5 TRM7AAP6 Acetaminophen / Tramadol HCl ER 울트라셋이알서방정 650mg/75mg ER tab 6 BPPO15 Bupropion XL 웰부트린엑스엘정 150mg XL tab 7 ECTLPR2 Escitalopram oxalate 렉사프로정 20mg tab 8 MMT50 Memantine HCl 에빅사액 10mg/g, 50g btl 9 BH41 apropterin HCl 쿠반정 mg tab 10 FVXM1 Fluvoxamine 듀미록스정 mg tab 7 월 18 일 11 VNC05 Varenicline 챔픽스정 0.5mg tab 12 VNC1 Varenicline 챔픽스정 1mg tab 13 PRG5 Prasugrel HCl 에피언트정 5mg tab 14 PRG10 Prasugrel HCl 에피언트정 10mg tab 15 HPR Heparin sodium 휴온스헤파린나트륨주사 1,000U/10ml vial 16 PMPX0375 Pramipexole ER 미라펙스서방정 0.375mg ER tab 17 PMPX075 Pramipexole ER 미라펙스서방정 0.75mg ER tab 18 PMPX15 Pramipexole ER 미라펙스서방정 1.5mg ER tab 19 ALD1LT5 Amlodipine camsylate / Losartan K 아모잘탄정 10mg/50mg tab 20 ALD1LT5 Amlodipine camsylate / Losartan K 코자엑스큐정 10mg/50mg tab 7 월 21 일 21 CALD05 CaCO 3/Cholecalciferol 디카맥스 500 츄어블정 22 CAL1D1 CaCO 3/Cholecalciferol 디카맥스디정 1,875mg(Ca 750mg) / 500IU Chewable tab 250mg(Ca mg) / 1,000IU tab 23 ELAP Asparaginase(Erwinia-L) 에르위나제주 10,000IU vial 7 월 27 일 2) 코드중단 NO 약품 CODE 성분명제품명규격및제형코드중단일 1 DLT1I Dolasetron 안제메트주 mg/5ml amp 7월 11일 2 PCB treptococcus pyogenese 피시바닐주 1KE inj 7월 21일

약제부소식 약학대학학생병원약학실습성료 다양한업무와약물들을접할수있어서병원약사에대해좀더알수있었다.

- 소감문에서발췌 외국약대학생병원약학실습성료 학회및교육참석 1) 7 월약제세미나 - 7/7( 목 )

of Washington) / 김시운 (Loma Linda University) - 7/14( 목

8 약제부소식 약학대학학생병원약학실습성료 다양한업무와약물들을접할수있어서병원약사에대해좀더알수있었다. 같은진로를생각하는친구들을만나고선배약사님들로부터조언을들을수있어서좋았다. - 소감문에서발췌 외국약대학생병원약학실습성료 학회및교육참석 1) 7 월약제세미나 - 7/7( 목 ) : 외국약대학생발표 I - 김건수 (U. of Washington) / 김시운 (Loma Linda University) - 7/14( 목 ) : 약제관련보험업무소개 - 보험심사팀차영미파트장 - 7/21( 목 ) : 외국약대학생발표 II - 정아름 (U. of Maryland) / 이자영 (U. of Maryland) 약제부기자박향미

< C6F7C0E5BEE0C7B0C0C720C1B6C1A620B9D720BAB9BEE05FB0A8BCF6BFCFB7E15FBDC5BFEBB9AE2E687770>

< C6F7C0E5BEE0C7B0C0C720C1B6C1A620B9D720BAB9BEE05FB0A8BCF6BFCFB7E15FBDC5BFEBB9AE2E687770> PTP 포장약품의조제및복약시 고려사항 저자구본기인제대학교일산백병원약제부장약학정보원학술자문위원 개요 PTP는 press through pack( 또는 package) 으로알려져있으며, 약품의휴대및보관의편의성때문에비용의부담에도불구하고흔히약품포장에이용되고있다. 특히일반포장에비해습기, 온도및빛에의한변색 변질로부터영향을적게받는특징이있어공기에노출되었을때물리 화학적으로변화가일어나기쉬운제제를