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練度率 1 1 2 1 立練 2 立練不度 6 4 女 2 年 24±1.1 169±6.2cm 66±8.1kg (21%) (15%) 行 10 V4 量 2min 30s 兩 48 參數率度數 t 行兩 (15%) 5 (5x) +0.42mmol/l (p>0.05) 1min(E1) 7min(E7) 10min 降度 15min 率 (p>0.05) 論兩率狀量 (15%) 練量降度量 V4 度

Effect of normal oxygen and hypoxic interval training on SPO 2 blood lactate and heart rate in human Abstract Purpose: The purpose of the study was to investigate the effect of different oxygen concentration on blood lactate and heart rate.subjects were six institute of physical education student( four male, two female), their average years, height, weight were 24±1.1 years, 169±6.2cm, 66±8.1kg, respectively.methods: Training plan was 10 time interval training in treadmill running machine, intensity was two minutes anaerobic threshold velocity 4,resting 48 hours after test one. Bio-parameter were blood lactate, heart rate,blood oxygen saturated concentration. The all data were analyze twice by dependent t test. Result The blood lactate accumulation (5x)of hypoxic(15%) was higher than normal oxygen +0.42mmol/l (p>0.05), E1, E7 of hypoxic was higher than normal oxygen, but E10 was lower normal oxygen, E15 was equal. Heart rate was no significant change in two conditions (p>0.05).result: blood lactate and heart rate were no significant difference in two conditions, this result might be induce by intensity. In the future, training should use hypoxic training (15%) and the intensity should be higher than normal oxygen, or decrease oxygen concentration, and then could improve energy metabolism of muscle and body circulation system. Key word : normal oxygen, hypoxic, anaerobic threshold velocity 4

論 Davidson and Stalcup(1984) (PaO2=60mmHg) 量 (+25%) (+15%) 流流量度年來力練粒 (Hood, 2001) 糖數量 (Ren, Semenkovich, Gulve, Gao, & Holloszy, 1994) 度 (Gute, Fraga, Laughlin, & Amann,1996) 理力 (Dufour et al., 2006; Ponsot et al., 2006; Zoll et al., 2006) 力力練練 (Interval hypoxic training) 練 (Training High Living Low) 練 (Living High Training Low) 練行練不練 Rodriguez(2000) Katayama(2004) 亮 (2006) 理刺了 ( 龍雷 2000) 更量更利力 ( 李 2007) Karlsen(2002) Vallier(1996) 見 ( 亮 2006) 練力練兩不論不論練練量不 - (15%O 2 )- (20%O 2 )- (15%O 2 )- (20%O 2 ) 練若練 (15%O 2 ) 練來練理練不便練理練率

4 2 女參年 24.3±1.11 說參料 1 1 料 N=6 (cm) (kg) 年 ( ) M±SD 168.5±6.24 65.8±8.09 24.3±1.11 h/p/cosmos pulsar 3p 4.0 率 Polar 610i( 蘭 ) ( ) 立 ( ) Pulse Oximeter Oxiheart OX-700 六 EFK 糖 (DiagnosticBiosen C_line) (PocketChem BAPA-4130) 流力 Mader 1976 2~4mmol/l 力理論立行 20%O 2 15% O 2 兩 48 Polar 率錄

率度 2.3 m/s 5min 度 0.3 m/s 30s 10 µl 行 all-out 4mmol/l 度 2 練行 10 2min (V4) 30s 1 參數率 (polar 610i 蘭 ) 率 5min(E5) 度 Spo2 lactate 3 5 7 1 3 5 7 10 15 time 1 練 2 4mmol/l 度 N=6 Speed(m/s) HR(min -1 ) 20% 2.8±0.3 163.8±10 15% 2.3±0.3 159.2±9.5 Diff 0.5 4.6±0.5 p 0.05 料理 Microsoft Office Excel 行 t 林 Laktat-Explorer 度 SigmaPlot 8.0 α 0.05

參論 7 6 20% 15% 5 La(mmol/l) 4 3 2 1 0 R 3x 5x 7x E1 E3 E5 E7 E10 E15 2 練練不 5 練度 7 3.8±0.4 mmol/l 練 3 狀練兩異 (p 0.05) Friedmann (2004) 利 (FiO 2 0.15) IAT 行略異 (p 0.05) 練 1min(E1) 15min(E15) 降 7min(E7) 降度狀練度練復更 (2002) LDH CK ALP 降了利 15 練 3.35±0.2 mmol/l 練 3.8±0.4mmol/l 兩不異練量度異 (p.05) 2 度數練度練 15min, 異不不

練度度 105 100 95 Spo2(20%) Spo2(15%) HR(20%) HR(15%) 180 160 Spo2(%) 90 85 140 120 HR(min -1 ) 80 75 100 70 1x 2x 3x 4x 5x 6x 7x 8x 9x 10x E3 E5 80 3 練度率練 1 練度 (Spo2) 狀練練 1 (1x) 5 (5x) 不練兩刺 ( 李 2007) 度練 5 狀練率 150±4.9 min -1 149±4.1 min -1 兩異率度練度兩率練量度率 Kontos et al. 1967 Vogel & Harris 1967 不論度率度率理論

論行練兩度率狀量練度練度 (15%) 練量降度量參亮 (2006) 不力論 : 立 (2002) 度度 9 6 52-53 李 (2007) 練 HiLi 練練練練 ( 練 ) 理論 22 2 115~120 龍雷 (2000) : 練 J 4 29~32 Davidson, D., & Stalcup, S. A. (1984). Systemic circulatory adjustments to acute hypoxia and reoxygenation in unanesthetized sheep: Role of renin, angiotensin II, and catecholamine interactions.j Clin Invest, 73(2), 317-328 Dufour, S. P., Ponsot, E., Zoll, J., Doutreleau, S., Lonsdorfer-Wolf, E., Geny, B., et al. (2006). Exercise training in normobaric hypoxia in endurance runners. Improvement in aerobic performance capacity. J Appl Physiol,100(4),1238-1248. Friedmann, B., Bauer, T., Menold, E. & Bärtsch, P. (2004). Exercise with the intensity of the individual anaerobic threshold in acute hypoxia. Med. Sci. Sports Exerc., 36, 1737-1742. Gute, D., Fraga, C., Laughlin, M. H., & Amann, J.F. (1996). Regional changes in capillary Supply in skeletal muscle of high-intensity endurance-trained rats. J Appl Physiol,81(2), 619-626.

Hood, D. A. (2001). Plasticity in skeletal, cardiac, and smooth muscle: Invited review: Contractile activityinduced mitochondrial biogenesis in skeletal muscle. J Appl Physiol, 90(3),1137-1157. Katayama K, Sato K, Matsuo H, Ishida K, Iwasaki KI and Miyamura M.(2004).Effect of intermittent hypoxia on oxygen uptake during submaximal exercise in endurance athletes. Eur J Appl physiol.92:75-83. Karlsen, T., Madsen, O., Rolf, S., & Stray-Gundersen, J. (2002). Effects of 3 weeks hypoxic interval training on sea level cycling performance and hematological parameters. Medicine and Science in Sports and Exercise, 34(5), Supplement abstract 1250. Kontos, H.A., Levasseur,J.E., Richardson, D.W.et al.(1967) Comparative circulatory responses tosystemic hypoxia in man and in unanesthetized dog. J.Appl.physiol. 23,78-81. Mader, A., H. Liesen, H. Heck, H. Philippi, R.Rost, P. SchürcH, W. Hollmann.(1976) : Zur Beurteilung der sportartspezifischen Ausdauerleistungsfähigkeit im Labor. Sportarzt und Sportmedizin, 27(4): S. 80-88. Ponsot, E., Dufour, S. P., Zoll, J., Doutrelau, S.,N'Guessan, B., Geny, B., et al. (2006). Exercise training in normobaric hypoxia in endurance runners. II: Improvement of mitochondrial properties in skeletal muscle. J Appl Physiol, 100(4),1249-1257. Ren, J. M., Semenkovich, C. F., Gulve, E. A.,Gao, J., & Holloszy, J. O. (1994).Exercise induces rapid increases in GLUT4 expression, glucose transport capacity, and insulin-stimulated glycogen storage in muscle. J.Biol.Chem.,269(20),14396-14401. Rodriguez FA, Ventura JL, Casas M, Casas H, Pages T, Rama R et al. (2000). Erythropoietin acute reaction and haematological adaptations to short,intermittent hypobaric hypoxia. Eur J Appl physiol. 82:170-177. Vallier JM, Chateau P, Guezennec CY.(1996).Effects of physical training in a hypobaricchamber on the physical performance of competitive triathletes. Eur Appl Physiol.73:471-478. Vogel,J.A. & Harris,C.W. (1967). Cardiopulmonary responses of resting man during early exposure to high altitude. J.Appl.physiol. 23, 1124-8 Zoll, J., Ponsot, E., Dufour, S., Doutreleau, S., Ventura-Clapier, R., Vogt, M., et al. (2006). Exercise training in normobaric hypoxia in endurance runners. III: Muscular Adjustments of selected gene transcripts. J Appl Physiol,100(4), 1258-1266.