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1 Measuring health related quality of life using EQ-5D in South Korea - Based on the results of KNHANES and Public Health Weekly Report, KCDC 541
2 Table 1. General characteristics of study participants in KNHANES and unit : N(%) KNHANES KNHANES Male Female Male Female All 11,392 (46.1) 13,308 (53.9) 1,240 (41.6) 1,741 (58.4) Age group ,971 (17.3) 2,438 (18.3) 141 (11.4) 198 (11.4) ,605 (22.9) 2,815 (21.2) 247 (19.9) 388 (22.3) ,736 (24.0) 2,974 (22.3) 248 (20.0) 317 (18.2) ,880 (16.5) 2,005 (15.1) 205 (16.5) 300 (17.2) ,420 (12.5) 1,722 (12.9) 216 (17.4) 273 (15.7) ( 5.4) 1,034 ( 7.8) 161 (13.0) 211 (12.1) ( 1.4) 320 ( 2.4) 22 ( 1.8) 54 ( 3.1) Residence Dong 9,133 (80.2) 10,694 (80.4) 867 (69.9) 1251 (71.9) Eup or Myeon 2,259 (19.8) 2,614 (19.6) 373 (30.1) 490 (28.1) Education Elementary or less 1,745 (15.7) 3,829 (29.5) 290 (23.4) 652 (37.6) Middle school 1,211 (10.9) 1,437 (11.1) 145 (11.7) 177 (10.2) High school 4,679 (42.2) 4,840 (37.2) 431 (34.8) 547 (31.5) University or more 3,465 (31.2) 2,893 (22.3) 371 (30.0) 360 (20.7) Occupation Non-manual 4,298 (37.7) 3,798 (28.5) 409 (33.0) 401 (23.0) Manual 4,253 (37.3) 2,271 (17.1) 421 (34.0) 277 (15.9) Others 2,841 (24.9) 7,239 (54.4) 410 (33.1) 1,063 (61.1) Subjective health Very good 651 ( 5.7) 447 ( 3.4) 66 ( 5.3) 40 ( 2.3) Good 5,089 (44.7) 4,753 (36.7) 367 (29.6) 447 (25.7) Moderate 3,793 (33.3) 4,859 (36.5) 585 (47.3) 814 (46.8) Bad 1,584 (13.9) 2,829 (21.3) 192 (15.5) 354 (20.3) Very bad 274 ( 2.4) 420 ( 3.2) 28 ( 2.3) 85 ( 4.9) The data without education or subjective health information were excluded for the analysis related to these variables. 542 Public Health Weekly Report, KCDC
3 Table 2. Crude problems reported(%) in EQ-5D and EQ VAS by general characteristics in KNHANES, 2005 Mobility Self-care Usual activities Pain/discomfort Anxiety/depression EQ VAS Mean (SD) Median (IQR) All population (16.9) 75.0 (20.0) Sex Male (16.2) 80.0 (15.0) Female (17.3) 70.0 (20.0) Age (14.3) 80.0 (20.0) (14.4) 80.0 (15.0) (15.8) 80.0 (20.0) (17.3) 70.0 (20.0) (18.2) 70.0 (30.0) (18.5) 60.0 (25.0) (18.8) 60.0 (20.0) Education Elementary or less (18.7) 60.0 (30.0) Middle school (17.1) 70.0 (20.0) High school (15.2) 80.0 (15.0) University or more (14.3) 80.0 (20.0) Occupation Non-manual (14.5) 75.0 (16.0) Manual (16.5) 70.0 (20.0) Others (18.1) 70.0 (20.0) Subjective Very good (12.8) 90.0 (15.0) health Good (12.2) 80.0 (20.0) Moderate (14.0) 70.0 (20.0) Bad (16.3) 60.0 (20.0) Very bad (19.7) 45.0 (24.0) Table 3. Crude problems reported(%) in EQ-5D and EQ VAS by general characteristics in KNHANES -1, 2007 Mobility Self-care Usual activities Pain/discomfort Anxiety/depression EQ VAS Mean (SD) Median (IQR) All population (18.1) 70.0 (20.0) Sex Male (16.2) 75.0 (20.0) Female (19.2) 70.0 (28.0) Age (14.9) 75.0 (17.0) (15.0) 75.0 (16.0) (15.4) 75.0 (20.0) (17.5) 75.0 (30.0) (19.8) 70.0 (30.0) (22.4) 63.0 (30.0) (26.1) 70.0 (40.0) Education Elementary or less (21.6) 70.0 (30.0) Middle school (17.2) 70.0 (20.0) High school (15.7) 75.0 (20.0) University or more (14.3) 80.0 (15.0) Occupation Non-manual (14.5) 75.0 (16.0) Manual (16.5) 70.0 (20.0) Others (20.1) 70.0 (30.0) Subjective Very good (10.8) 90.0 (15.0) health Good (13.7) 80.0 (20.0) Moderate (14.9) 70.0 (20.0) Bad (19.0) 60.0 (20.0) Very bad (21.8) 50.0 (40.0) Public Health Weekly Report, KCDC 543
4 Table 4. Difference between EQ-5D problem reporting and EQ VAS of KNHANES & -1 after socio-demographic factors adjustments Variables Mobility Self-care Usual activities Pain/discomfort Anxiety/depression EQ VAS OR p OR p OR p OR p OR p p Before Adjusted Adjusted* * Adjustments for socio-demographic factors such as sex, age, education, occupation, and residence Table 5. International comparison of EQ-5D problem rate and EQ VAS after age and sex standardization. Country Sample Mobility Self-care Usual Pain/ Anxiety/ EQ (investigation year) size activities discomfort depression VAS (N) (%) (%) (%) (%) (%) (score) Korea (2005) 24, Korea (2007) 2, Armenia (2002) 2, Belgium (2001) 1, Canada (1997) 1, Finland (1992) 2, Germany (1994, 1997, 1996) Greece (1998) Hungary (2000) 5, Japan (1998) The Netherlands (1991) The Netherlands (2001) 9, New Zealand (1999) 1, Slovenia (2000) Spain (1995, 1996,1999) 2, Sweden (1994, 1998) 3, UK (1993) 3, USA (2000) 13, Zimbabwe (2003) 2, Public Health Weekly Report, KCDC
5 Figure 1. Correlation between problem rate in each EQ-5D and EQ VAS and GNI per capita in 19 studies Public Health Weekly Report, KCDC 545
6 Serosurvey of human brucellosis, Q fever among livestock hygiene controllers, Public Health Weekly Report, KCDC
7 Table 1. Regional distribution of livestock hygiene controllers by region and gender Region Livestock hygiene controllers Male Female Total (%) Gyeonggi (16.8) Gangwon (7.9) Chungbuk (6.9) Chungnam (13.4) Jeonbuk (10.4) Jeonnam (13.4) Gyeongbuk (16.8) Gyeongnam (12.9) Jeju (1.5) Total (100.0) Public Health Weekly Report, KCDC 547
8 Table 2. Seroprevalence of brucellosis, Q fever among the livestock hygiene controllers No. of seropositivity Seroprevalence % Total Brucellosis Q fever Public Health Weekly Report, KCDC
9 Case reports of transfusion-transmitted malaria confirmed on epidemiological investigation Public Health Weekly Report, KCDC 549
10 Figure 1. The weekly proportion of influenza-like illness visits per 1,000 patients, season season Figure 2. The number of influenza virus isolates, season Figure 3. The weekly reported Malaria cases through National Notifiable Disease Surveillance System Figure 4. Cumulative reported Malaria cases through National Notifiable Disease Surveillance System All Causes 265* P&I 17* * Mortality data in this table are voluntarily reported from 40 hospitals, which of total discharged patients in 31 th week, 2009 are 15,756 All causes of death are defined from death certificates. Fetal deaths are not included. Pneumonia and influenza (KCD code J09-J18). 550 Public Health Weekly Report, KCDC
11 Cholera Plague - Typhoid fever Paratyphoid fever Shigellosis Philippines(1) EHEC Diphtheria - Pertussis Tetanus Measles Mumps 153 4, ,542 4,557 2,089 1,863 1,744 Rubella Poliomyelitis - Japanese encephalitis Varicella , ,849 20,284 11,027 1,934 - Malaria ,052 2,227 2,051 1, Equatorial Guinea(1) Scarlet fever Meningococcal meningitis Legionellosis Malaysia(1) Vibrio vulnificus sepsis Epidemic typhus - Murine typhus Scrub typhus ,057 6,022 6,480 6,780 4,698 Leptospirosis Brucellosis Anthrax - Rabies 1 HFRS Dengue fever Leishmaniasis 1 Babesiosis Cryptosporidiosis Botulism Q fever Tuberculosis , ,157 34,710 35,361 35,269 31,503 HIV/AIDS : No reported cases. N : Not notifiable. Cum: Cumulative counts of the year from 1st week to current week. EHEC : Enterohemorrhagic Escherichia coli. HFRS : Hemorrhagic fever with renal syndrome. * Incidence data for reporting years 2009 are provisional, whereas data for 2004, 2005, 2006, 2007 and 2008 are finalized. * Reported cases contain all case classifications (Confirmed, Suspected, Asymptomatic carrier) of the disease respectively. Excluding Hansen's disease and diseases reported through the Laboratory Surveillance System and Sentinel Surveillance System(Data for Sentinel Surveillance System are available in Table III) and no case reported since 2003(Yellow fever, Marburg fever, Ebola fever, Lassa fever, African Trypanosomiasis, Schistosomiasis, Yaws, Pinta, Smallpox, Severe Acute Respiratory Syndrome, Avian influenza infection and humans, Tularemia, and Newly everging infectious disease syndrome) Calculated by summing the incidence counts for the current week, the 2 weeks preceding the current week, and the 2 weeks following the current week, for a total of 5 preceding years.(in case of Varicella, used data for 3 years-2006,2007 and 2008, because of being designated as of July 13, 2005) HIV/AIDS is infected cases but not disease cases. Public Health Weekly Report, KCDC 551
12 Total ,442 1,831 Seoul Busan Daegu Incheon , Gwangju Daejeon Ulsan Gyeonggi , Gangwon Chungbuk Chungnam Jeonbuk Jeonnam Gyeongbuk Gyeongnam Jeju : No reported cases. Cum: Cumulative counts of the year from 1st week to current week. * Incidence data for reporting years 2009 are provisional, whereas data for 2004, 2005, 2006, 2007 and 2008 are finalized. Reported cases contain all case classifications (Confirmed, Suspected, Asymptomatic carrier) of the disease, respectively. Calculated by averaging the cumulative counts from 1st week to current week, for a total of 5 preceding years. Public Health Weekly Report, KCDC 552
13 Total ,976 11, Seoul , Busan ,140 1, Daegu , Incheon , Gwangju Daejeon Ulsan Gyeonggi ,379 2, Gangwon ,284 1, Chungbuk Chungnam Jeonbuk Jeonnam Gyeongbuk Gyeongnam Jeju unknown : No reported cases. Cum: Cumulative counts of the year from 1st week to current week. * Incidence data for reporting years 2009 are provisional, whereas data for 2004, 2005, 2006, 2007 and 2008 are finalized. Reported cases contain all case classifications (Confirmed, Suspected, Asymptomatic carrier) of the disease, respectively. Calculated by averaging the cumulative counts from 1st week to current week, for a total of 5 preceding years. (In case of Varicella, used data for 3 years , 2007 and 2008, because of being designated as of July 13, 2005) Public Health Weekly Report, KCDC 553
14 Total ,474 20,179 Seoul ,108 5,632 Busan ,186 2,040 Daegu , Incheon , Gwangju Daejeon Ulsan Gyeonggi ,441 3,230 Gangwon Chungbuk Chungnam Jeonbuk Jeonnam Gyeongbuk Gyeongnam ,400 1,299 Jeju : No reported cases. Cum: Cumulative counts of the year from 1st week to current week. * Incidence data for reporting years 2009 are provisional, whereas data for 2004, 2005, 2006, 2007 and 2008 are finalized. Reported cases contain all case classifications (Confirmed, Suspected, Asymptomatic carrier) of the disease, respectively. Calculated by averaging the cumulative counts from 1st week to current week, for a total of 5 preceding years. Public Health Weekly Report, KCDC 554
15 : No reported cases. Cum: Cumulative counts of the year from 1st week to current week. * Incidence data for reporting years 2008 and 2009 are provisional. Reported cases contains all case classifications (Confirmed, Suspected, Asymptomatic carrier) of the disease, respectively. Calculated by averaging the cumulative counts from 1st week to current week, for a total of 5 preceding years. Included stage I and II of Syphilis. Public Health Weekly Report, KCDC 555
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