Review Article Psychoanalysis 2014;25(2):54-64 pissn / eissn Copyright c 2014 Korean Association of Psychoanalysis Anxiety and Fea

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1 Review Article Psychoanalysis 2014;25(2):54-64 pissn / eissn Copyright c 2014 Korean Association of Psychoanalysis Anxiety and Fear Development: From the Psychoanalysis to the Neurobiological Approach Geon Ho Bahn Department of Psychiatry, Kyung Hee University School of Medicine, Seoul, Korea 불안및공포의발달 : 정신분석부터신경생물학적접근까지 반건호 경희대학교의학전문대학원정신건강의학교실 Anxiety and fear are the essential emotion for the protection of the individual from threat and the reproduction for the preservation of the species. Freud s anxiety theory was developed primarily from compromised formation of conflicts, which was based on the libido theory, and later, signal anxiety theory, which was based on ego structures. In Bowlby s attachment theory, it is known that the quality of the infant s attachment determines the level of anxiety response afterwards, and affects the sociality and formation of interpersonal relationships in the adulthood. Although anxiety and fear are used as a similar concept, through animal experiments and human studies, the correlation between brain development and anxiety and fear, along with specific brain regions and related substances affecting the development of anxiety and fear, is continuously being discovered. Such research results may lead to the development of personalized tailored treatment for anxiety and fear of normal and mentally disabled people. Psychoanalysis 2014;25(2):54-64 KEY WORDS: Anxiety Fear Attachment Treatment Animal Brain. Received: May 16, 2014 Revised: June 16, 2014 Accepted: June 20, 2014 Address for correspondence: Geon Ho Bahn, MD, PhD Department of Psychiatry, Kyung Hee University School of Medicine, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul , Korea Tel: , Fax: , mompeian@khu.ac.kr This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

2 GH Bahn Table 1. Summary of differences between fear and anxiety Anxiety Items Fear Not present but anticipated Cause of threat Explicit cues or traumatic events earlier in life Increased capacity to adapt & plan for the future Function Protect the individual from an immediate threat Long-term (sustained) Activation pattern Short-term (phasic) Conditioned Conditioning Unconditioned Cognitive and complex cognitions Cognitions Automatic Verbal/worry Sensory process Visual/imagery Lateral bed nucleus of stria terminalis Locus of system Central nucleus of the amygdala

3 Anxiety and Fear Development - Freud Psychoanalysis 2014;25(2):54-64

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5 Anxiety and Fear Development -? - - (Sensitive period)? 58 Psychoanalysis 2014;25(2):54-64

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7 Anxiety and Fear Development -? Oxytocin과 arginine vasopressin Psychoanalysis 2014;25(2):54-64

8 GH Bahn 중추신경계관련물질?

9 Anxiety and Fear Development - - Acknowledgments The theme of this article was presented at the annual meeting of the Korean Academy of Child and Adolescent Psychiatry on 10th May, 2014 at Severance Hospital, Seoul. Conflicts of Interest The author has no financial conflicts of interest. REFERENCES American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed. Washington, DC: American Psychiatric Association;1980. Bahn GH. From attachment theory to mentalization: historical background and clinical implications. Psychoanalysis 2013;24:9-20. Barlow DH. Unraveling the mysteries of anxiety and its disorders from the perspective of emotion theory. Am Psychol 2000;55: Beard G. Neurasthenia, or nervous exhaustion. Boston Med Surg J 1869; 80: Blanchard DC, Griebel G, Nutt DJ. Handbook of anxiety and fear. Amsterdam: Elsevier Academic Press;2008. Blass RB. On the fear of death as the primary anxiety: How and why Klein differs from Freud. Int J Psychoanal 2014;95: Bowlby J. A secure base: clinical applications of attachment theory. London: Routledge;1988. Bracha HS, Ralston TC, Matsukawa JM, Williams AE, Bracha AS. Does fight or flight need updating? Psychosomatics 2004;45: Psychoanalysis 2014;25(2):54-64

10 GH Bahn Bremner JG, Wachs TD. The Wiley-Blackwell handbook of infant development. 2nd ed. Oxford: Wiley-Blackwell;2010. p Brenner C. Psychoanalytic technique and psychic conflict. New York: International Universities Press;1976. Choleris E, Pfaff DW, Kavaliers M. Oxytocin, vasopressin, and related peptides in the regulation of behavior. Cambridge: Cambridge University Press;2013. p Chugani HT, Behen ME, Muzik O, Juhász C, Nagy F, Chugani DC. Local brain functional activity following early deprivation: a study of postinstitutionalized Romanian orphans. Neuroimage 2001;14: Chugani HT, Phelps ME. Maturational changes in cerebral function in infants determined by 18FDG positron emission tomography. Science 1986;231: Dalgleish T, Power MJ. Handbook of cognition and emotion. Chichester: J. Wiley & Sons;1999. p Davidson RJ. Affective style, psychopathology, and resilience: brain mechanisms and plasticity. Am Psychol 2000;55: Davidson RJ, Kalin NH, Shelton SE. Lateralized effects of diazepam on frontal brain electrical asymmetries in rhesus monkeys. Biol Psychiatry 1992;32: Davis M. Are different parts of the extended amygdala involved in fear versus anxiety? Biol Psychiatry 1998;44: De Bianchedi ET, Scalozub De Boschan L, De Cortiñas LP, De Piccolo EG. Theories on anxiety in Freud and Melanie Klein. Their metapsychological status. Int J Psychoanal 1988;69(Pt 3): Dewald PA. Psychotherapy: a dynamic approach. New York: Basic Books; p Donohue JM, Cevasco M, Rosenthal MB. A decade of direct-to-consumer advertising of prescription drugs. N Engl J Med 2007;357: Editors of Scientific American Magazine. The Scientific American Book of the Brain. New York: The Lyons Press;1999. p Fotopoulou A, Pfaff DW, Conway MA. From the couch to the lab: trends in psychodynamic neuroscience. Oxford: Oxford University Press; p Freud S. Inhibitions, symptoms and anxiety. SE 20. London: Hogarth Press;1926. p Ganella DE, Kim JH. Developmental rodent models of fear and anxiety: from neurobiology to pharmacology. Br J Pharmacol 2014;171: Gibbs DM, Vale W, Rivier J, Yen SS. Oxytocin potentiates the ACTH-releasing activity of CRF(41) but not vasopressin. Life Sci 1984;34: Gibson EJ, Walk RD. The visual cliff. Sci Am 1960;202: Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L, et al. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 2002;416: Holmes J. John Bowlby and attachment theory. New York: Routledge;1993. Horwitz AV, Wakefield JC. All we have to fear: psychiatry s transformation of natural anxieties into mental disorders. New York: Oxford University Press;2012. Ibragimov RSh. Influence of neurohypophyseal peptides on the formation of active avoidance conditioned reflex behavior. Neurosci Behav Physiol 1990;20: Kagan J. On the nature of emotion. Monogr Soc Res Child Dev 1994;59:7-24. Kagan J, Reznick JS, Snidman N. Biological bases of childhood shyness. Science 1988;240: Kagan J, Snidman N, Julia-Sellers M, Johnson MO. Temperament and allergic symptoms. Psychosom Med 1991;53: Kalin NH, Shelton SE. Defensive behaviors in infant rhesus monkeys: environmental cues and neurochemical regulation. Science 1989;243: Kalin NH, Shelton SE, Davidson RJ. Role of the primate orbitofrontal cortex in mediating anxious temperament. Biol Psychiatry 2007;62: Kalin NH, Shelton SE, Davidson RJ. The role of the central nucleus of the amygdala in mediating fear and anxiety in the primate. J Neurosci 2004;24: Kalin NH, Shelton SE, Davidson RJ, Kelley AE. The primate amygdala mediates acute fear but not the behavioral and physiological components of anxious temperament. J Neurosci 2001;21: Kalin NH, Shelton SE, Rickman M, Davidson RJ. Individual differences in freezing and cortisol in infant and mother rhesus monkeys. Behav Neurosci 1998;112: Kalin NH, Shelton SE, Turner JG. Effects of beta-carboline on fear-related behavioral and neurohormonal responses in infant rhesus monkeys. Biol Psychiatry 1992;31: Kandel E. The new science of mind and the future of knowledge. Neuron 2013;80: Kaplan-Solms K, Solms M. Clinical studies in neuro-psychoanalysis: introduction to a depth neuropsychology. London: Karnac Books;2000. p Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005;62: Kiel EJ, Buss KA. Toddler inhibited temperament, maternal cortisol reactivity and embarrassment, and intrusive parenting. J Fam Psychol 2013;27: Klein M. Notes on some schizoid mechanisms. Int J Psychoanal 1946; 27(Pt 3-4): Kraepelin E. Psychiatrie: ein Lehrbuch für Studirende und Aerzte. 5th ed. Leipzig: Johann Ambrosius Barth;1896. Leavitt HC. Generic relations between anxiety and fear. Psychoanal Rev 1957;44: LeDoux JE, Iwata J, Cicchetti P, Reis DJ. Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear. J Neurosci 1988;8: Mahler MS. Symbiosis and individuation. The psychological birth of the human infant. Psychoanal Study Child 1974;29: Marks IM. Fears, phobias, and rituals: panic, anxiety, and their disorders. New York: Oxford University Press;1987. McNaughton N, Corr PJ. A two-dimensional neuropsychology of defense: fear/anxiety and defensive distance. Neurosci Biobehav Rev 2004;28: Meaney MJ, Aitken DH, Bodnoff SR, Iny LJ, Tatarewicz JE, Sapolsky RM. Early postnatal handling alters glucocorticoid receptor concentrations in selected brain regions. Behav Neurosci 2013;127: Mintz D. Psychodynamic Trojan horses: using psychopharmacology to teach psychodynamics. J Am Acad Psychoanal Dyn Psychiatry 2006; 34: Moffitt TE, Caspi A, Taylor A, Kokaua J, Milne BJ, Polanczyk G, et al. How common are common mental disorders? Evidence that lifetime prevalence rates are doubled by prospective versus retrospective ascertainment. Psychol Med 2010;40: Nelson CA, Fox NA, Zeanah CH. Romania s Abandoned Children. Cambridge, MA: Harvard University Press;2014. Neumann ID, Wigger A, Torner L, Holsboer F, Landgraf R. Brain oxytocin inhibits basal and stress-induced activity of the hypothalamo-pituitary-adrenal axis in male and female rats: partial action within the paraventricular nucleus. J Neuroendocrinol 2000;12: Pfaff DW, Phillips MI, Rubin RT. Principles of hormone/behavior relations. Amsterdam: Elsevier Academic Press;2004. Plakun EM. Finding psychodynamic psychiatry s lost generation. J Am Acad Psychoanal Dyn Psychiatry 2006;34:

11 Anxiety and Fear Development Poulton R, Menzies RG. Non-associative fear acquisition: a review of the evidence from retrospective and longitudinal research. Behav Res Ther 2002;40: Rachman S. Anxiety. 3rd ed. New York: Psychology Press;2013. Regier DA, Kaelber CT, Rae DS, Farmer ME, Knauper B, Kessler RC, et al. Limitations of diagnostic criteria and assessment instruments for mental disorders. Implications for research and policy. Arch Gen Psychiatry 1998;55: Reynolds RM, Walker BR, Syddall HE, Andrew R, Wood PJ, Whorwood CB, et al. Altered control of cortisol secretion in adult men with low birth weight and cardiovascular risk factors. J Clin Endocrinol Metab 2001;86: Schapiro S, Geller E, EIduson S. Corticoid response to stress in the steroid-inhibited rat. Proc Soc Exp Biol Med 1962;109: Shackman AJ, Fox AS, Oler JA, Shelton SE, Davidson RJ, Kalin NH. Neural mechanisms underlying heterogeneity in the presentation of anxious temperament. Proc Natl Acad Sci U S A 2013;110: Spielberger CD. Anxiety: current trends in theory and research. New York: Academic Press;1972. Takahashi LK, Turner JG, Kalin NH. Prenatal stress alters brain catecholaminergic activity and potentiates stress-induced behavior in adult rats. Brain Res 1992;574: Tone A, Watkins ES. Medicating modern America: prescription drugs in history. New York: New York University Press;2007. p Tuan YF. Landscapes of fear. New York: Pantheon;1979. Viviani D, Stoop R. Opposite effects of oxytocin and vasopressin on the emotional expression of the fear response. Prog Brain Res 2008;170: Waska RT. Schizoid anxiety: a reappraisal of the manic defense and the depressive position. Am J Psychother 2001;55: Yagi K, Onaka T. Chlordiazepoxide discriminates between the neural circuits mediating neuroendocrine responses to fear- and anxiety-producing stimuli in the rat. Neurosci Res 1996;24: Psychoanalysis 2014;25(2):54-64

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